Aniseed - Gene card

Gene Card

Best human hits

ADRA2C; DRD2; HRH1

Species

P.mammillata

Unique Gene ID

Phmamm.g00000255

Gene Model ID

Phmamm.CG.MTP2014.S5.g00255

Location

S5:393129..408243

Transcript Models and Sequences

Phmamm.CG.MTP2014.S5.g00255.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term	Analysis	Definition
GPCR_Rhodpsn	ProSitePatterns	G protein-coupled receptor, rhodopsin-like
GPCR_Rhodpsn	Pfam	G protein-coupled receptor, rhodopsin-like
GPCR_Rhodpsn_7TM	ProSiteProfiles	GPCR, rhodopsin-like, 7TM
GPCR_Rhodpsn	PRINTS	G protein-coupled receptor, rhodopsin-like

GOSlim

70 results

GO Term	Annotation Origin	Type
signal transducer activity	Orthology	molecular function
G-protein coupled receptor activity	Orthology	molecular function
receptor binding	Orthology	molecular function
protein binding	Orthology	molecular function
cytoplasm	Orthology	cellular component
endosome	Orthology	cellular component
cytosol	Blast	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Orthology	cellular component
signal transduction	Orthology	biological process
G-protein coupled receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
axon	Orthology	cellular component
cytoplasmic vesicle	Blast	cellular component
identical protein binding	Blast	molecular function
protein homodimerization activity	Orthology	molecular function
protein heterodimerization activity	Orthology	molecular function
intracellular	Orthology	cellular component
positive regulation of cell proliferation	Orthology	biological process
basolateral plasma membrane	Orthology	cellular component
protein kinase binding	Orthology	molecular function
blood coagulation	Orthology	biological process
cellular process	Orthology	biological process
positive regulation of catalytic activity	Orthology	biological process
protein kinase activity	Orthology	molecular function
intracellular signal transduction	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
protein phosphorylation	Orthology	biological process
cell projection part	Orthology	cellular component
synapse part	Orthology	cellular component
cell development	Orthology	biological process
neuron differentiation	Orthology	biological process
protein transport	Orthology	biological process
regulation of signaling	Orthology	biological process
organic cyclic compound binding	Orthology	molecular function
sensory perception	Orthology	biological process
regulation of catalytic activity	Orthology	biological process
regulation of signal transduction	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
negative regulation of signal transduction	Orthology	biological process
small GTPase mediated signal transduction	Orthology	biological process
organelle organization	Orthology	biological process
cell migration	Orthology	biological process
enzyme binding	Orthology	molecular function
macromolecular complex binding	Orthology	molecular function
cellular response to organic substance	Orthology	biological process
macromolecular complex	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
transmembrane signaling receptor activity	Orthology	molecular function
metal ion transport	Orthology	biological process
wound healing	Orthology	biological process
cation binding	Blast	molecular function
endomembrane system	Blast	cellular component
heterocyclic compound binding	Blast	molecular function
binding	Blast	molecular function
organelle	Blast	cellular component
postsynapse	Blast	cellular component
neuron part	Blast	cellular component
plasma membrane part	Blast	cellular component
whole membrane	Blast	cellular component
bounding membrane of organelle	Blast	cellular component
intracellular organelle part	Blast	cellular component
microtubule	Blast	cellular component
cytoplasmic part	Blast	cellular component
plasma membrane region	Blast	cellular component
neuronal cell body	Blast	cellular component
cell projection membrane	Blast	cellular component
cell projection	Blast	cellular component

GO (Orthology)

59 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
signal transducer activity	Hs	molecular function
G-protein coupled receptor activity	Hs	molecular function
adrenergic receptor activity	Hs	molecular function
alpha2-adrenergic receptor activity	Hs	molecular function
protein binding	Hs	molecular function
cytoplasm	Hs	cellular component
endosome	Hs	cellular component
plasma membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
regulation of smooth muscle contraction	Hs	biological process
signal transduction	Hs	biological process
G-protein coupled receptor signaling pathway	Hs	biological process
cell-cell signaling	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
regulation of vasoconstriction	Hs	biological process
platelet activation	Hs	biological process
axon	Hs	cellular component
alpha-2A adrenergic receptor binding	Hs	molecular function
activation of protein kinase activity	Hs	biological process
protein homodimerization activity	Hs	molecular function
positive regulation of MAPK cascade	Hs	biological process
axon terminus	Hs	cellular component
positive regulation of neuron differentiation	Hs	biological process
positive regulation of vasoconstriction	Hs	biological process
negative regulation of insulin secretion	Hs	biological process
protein heterodimerization activity	Hs	molecular function
regulation of insulin secretion	Hs	biological process
epinephrine binding	Hs	molecular function
regulation of sensory perception of pain	Hs	biological process
adrenergic receptor signaling pathway	Hs	biological process
adenylate cyclase-activating adrenergic receptor signaling pathway	Hs	biological process
activation of MAPK activity	Hs	biological process
positive regulation of cytokine production	Hs	biological process
intracellular	Hs	cellular component
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Hs	biological process
Ras protein signal transduction	Hs	biological process
Rho protein signal transduction	Hs	biological process
positive regulation of cell proliferation	Hs	biological process
basolateral plasma membrane	Hs	cellular component
protein kinase binding	Hs	molecular function
actin cytoskeleton organization	Hs	biological process
positive regulation of cell migration	Hs	biological process
alpha-1B adrenergic receptor binding	Hs	molecular function
alpha-2C adrenergic receptor binding	Hs	molecular function
thioesterase binding	Hs	molecular function
heterotrimeric G-protein binding	Hs	molecular function
cellular response to hormone stimulus	Hs	biological process
glucose homeostasis	Hs	biological process
receptor complex	Hs	cellular component
positive regulation of MAP kinase activity	Hs	biological process
positive regulation of epidermal growth factor-activated receptor activity	Hs	biological process
positive regulation of blood pressure	Hs	biological process
intestinal absorption	Hs	biological process
negative regulation of lipid catabolic process	Hs	biological process
norepinephrine binding	Hs	molecular function
negative regulation of calcium ion transport	Hs	biological process
adenylate cyclase-inhibiting adrenergic receptor signaling pathway	Hs	biological process
positive regulation of wound healing	Hs	biological process

GO (Blast)

38 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
dopamine neurotransmitter receptor activity, coupled via Gi/Go	Hs	molecular function	148	5.04e-40
acrosomal vesicle	Hs	cellular component	148	5.04e-40
signal transducer activity	Hs	molecular function	148	5.04e-40
G-protein coupled receptor activity	Hs	molecular function	148	5.04e-40
adrenergic receptor activity	Hs	molecular function	110	1.67e-26
alpha2-adrenergic receptor activity	Hs	molecular function	110	1.67e-26
dopamine neurotransmitter receptor activity	Hs	molecular function	148	5.04e-40
histamine receptor activity	Hs	molecular function	109	5.11e-26
receptor binding	Hs	molecular function	148	5.04e-40
protein binding	Hs	molecular function	148	5.04e-40
cytoplasm	Hs	cellular component	110	1.67e-26
endosome	Hs	cellular component	110	1.67e-26
cytosol	Hs	cellular component	109	5.11e-26
plasma membrane	Hs	cellular component	148	5.04e-40
integral component of plasma membrane	Hs	cellular component	148	5.04e-40
drug binding	Hs	molecular function	148	5.04e-40
postsynaptic density	Hs	cellular component	148	5.04e-40
membrane	Hs	cellular component	148	5.04e-40
integral component of membrane	Hs	cellular component	148	5.04e-40
lateral plasma membrane	Hs	cellular component	148	5.04e-40
endocytic vesicle	Hs	cellular component	148	5.04e-40
axon	Hs	cellular component	148	5.04e-40
dendrite	Hs	cellular component	148	5.04e-40
synaptic vesicle membrane	Hs	cellular component	148	5.04e-40
cytoplasmic vesicle	Hs	cellular component	148	5.04e-40
alpha-2A adrenergic receptor binding	Hs	molecular function	110	1.67e-26
dopamine binding	Hs	molecular function	148	5.04e-40
ionotropic glutamate receptor binding	Hs	molecular function	148	5.04e-40
sperm flagellum	Hs	cellular component	148	5.04e-40
identical protein binding	Hs	molecular function	148	5.04e-40
protein homodimerization activity	Hs	molecular function	148	5.04e-40
dendritic spine	Hs	cellular component	148	5.04e-40
perikaryon	Hs	cellular component	148	5.04e-40
axon terminus	Hs	cellular component	148	5.04e-40
protein heterodimerization activity	Hs	molecular function	148	5.04e-40
epinephrine binding	Hs	molecular function	110	1.67e-26
ciliary membrane	Hs	cellular component	148	5.04e-40
non-motile cilium	Hs	cellular component	148	5.04e-40

GO (InterProScan)

3 results

GO Term	Analysis	Type	e-value
G-protein coupled receptor activity	Pfam	molecular function	1.4E-53
G-protein coupled receptor signaling pathway	Pfam	biological process	1.4E-53
integral component of membrane	Pfam	cellular component	1.4E-53