Gene Card
Best human hits
AFG3L2; SPG7; YME1L1
Species
Unique Gene ID
Phmamm.g00000787
Gene Model ID
Phmamm.CG.MTP2014.S19.g00787
Location
S19:92836..106137
Transcript Models and Sequences
Phmamm.CG.MTP2014.S19.g00787.01.t
Phmamm.CG.MTP2014.S19.g00787.02.t
AHC0AAA29YA19
Plate: Plate_29_A19
AHC0AAA48YG09
Plate: Plate_48_G09
AHC0AAA50YL21
Plate: Plate_50_L21
AHC0AAA55YI05
Plate: Plate_55_I05
AHC0AAA72YL04
Plate: Plate_72_L04
AHC0AAA75YJ10
Plate: Plate_75_J10
AHC0AAA106YH10
Plate: Plate_106_H10
AHC0AAA107YJ03
Plate: Plate_107_J03
AHC0AAA116YH21
Plate: Plate_116_H21
AHC0AAA117YM12
Plate: Plate_117_M12
AHC0AAA134YH16
Plate: Plate_134_H16
AHC0AAA149YI18
Plate: Plate_149_I18
AHC0AAA81YL23
Plate: Plate_81_L23
AHC0AAA93YM03
Plate: Plate_93_M03
AHC0AAA106YJ12
Plate: Plate_106_J12
AHC0AAA179YM11
Plate: Plate_179_M11
AHC0AAA194YK10
Plate: Plate_194_K10
AHC0AAA212YE19
Plate: Plate_212_E19
AHC0AAA212YO15
Plate: Plate_212_O15
AHC0AAA229YB21
Plate: Plate_229_B21
AHC0AAA253YL14
Plate: Plate_253_L14
AHC0AAA55YK07
Plate: Plate_55_K07
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Pept_M41_FtsH_extracell | Pfam | Peptidase M41, FtsH extracellular |
ATPase_AAA_core | Pfam | ATPase, AAA-type, core |
AAA+_ATPase | SMART | AAA+ ATPase domain |
FtsH | Hamap | Peptidase, FtsH |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
FtsH | TIGRFAM | Peptidase, FtsH |
Peptidase_M41 | Pfam | Peptidase M41 |
Peptidase_M41-like | SUPERFAMILY | Peptidase M41-like |
ATPase_AAA_CS | ProSitePatterns | ATPase, AAA-type, conserved site |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
metalloendopeptidase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
mitochondrion | Orthology | cellular component |
mitochondrial inner membrane | Orthology | cellular component |
proteolysis | Orthology | biological process |
nervous system development | Orthology | biological process |
axonogenesis | Orthology | biological process |
peptidase activity | Orthology | molecular function |
metallopeptidase activity | Orthology | molecular function |
zinc ion binding | Orthology | molecular function |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
nuclear body | Blast | cellular component |
hydrolase activity | Orthology | molecular function |
metal ion binding | Orthology | molecular function |
unfolded protein binding | Orthology | molecular function |
macromolecular complex | Orthology | cellular component |
metal ion transport | Orthology | biological process |
transmembrane transport | Orthology | biological process |
organelle organization | Orthology | biological process |
cellular component organization | Orthology | biological process |
gene expression | Orthology | biological process |
developmental process | Orthology | biological process |
membrane organization | Orthology | biological process |
cellular process | Orthology | biological process |
cell development | Orthology | biological process |
peptidase activity, acting on L-amino acid peptides | Blast | molecular function |
nucleoside-triphosphatase activity | Blast | molecular function |
mitochondrial envelope | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
cell projection part | Blast | cellular component |
axon | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
metalloendopeptidase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
mitochondrion | Hs | cellular component |
mitochondrial inner membrane | Hs | cellular component |
m-AAA complex | Hs | cellular component |
proteolysis | Hs | biological process |
mitochondrial calcium ion transmembrane transport | Hs | biological process |
mitochondrion organization | Hs | biological process |
axonogenesis | Hs | biological process |
neuromuscular junction development | Hs | biological process |
mitochondrial fusion | Hs | biological process |
peptidase activity | Hs | molecular function |
metallopeptidase activity | Hs | molecular function |
zinc ion binding | Hs | molecular function |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
protein processing | Hs | biological process |
protein autoprocessing | Hs | biological process |
hydrolase activity | Hs | molecular function |
mitochondrial calcium uptake | Hs | biological process |
regulation of multicellular organism growth | Hs | biological process |
cristae formation | Hs | biological process |
myelination | Hs | biological process |
metal ion binding | Hs | molecular function |
muscle fiber development | Hs | biological process |
unfolded protein binding | Hs | molecular function |
mitochondrial calcium ion homeostasis | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 784 | 0.0 |
ATP-dependent peptidase activity | Hs | molecular function | 345 | 2.80e-108 |
metalloendopeptidase activity | Hs | molecular function | 784 | 0.0 |
protein binding | Hs | molecular function | 784 | 0.0 |
ATP binding | Hs | molecular function | 784 | 0.0 |
mitochondrion | Hs | cellular component | 784 | 0.0 |
mitochondrial inner membrane | Hs | cellular component | 784 | 0.0 |
m-AAA complex | Hs | cellular component | 784 | 0.0 |
mitochondrial permeability transition pore complex | Hs | cellular component | 499 | 1.56e-167 |
peptidase activity | Hs | molecular function | 784 | 0.0 |
metallopeptidase activity | Hs | molecular function | 784 | 0.0 |
zinc ion binding | Hs | molecular function | 784 | 0.0 |
membrane | Hs | cellular component | 784 | 0.0 |
integral component of membrane | Hs | cellular component | 784 | 0.0 |
nuclear body | Hs | cellular component | 345 | 2.80e-108 |
hydrolase activity | Hs | molecular function | 784 | 0.0 |
metal ion binding | Hs | molecular function | 784 | 0.0 |
unfolded protein binding | Hs | molecular function | 784 | 0.0 |
axon cytoplasm | Hs | cellular component | 499 | 1.56e-167 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
metalloendopeptidase activity | TIGRFAM | molecular function | 5.4E-195 |
ATP binding | SUPERFAMILY | molecular function | 1.15E-63 |
proteolysis | SUPERFAMILY | biological process | 1.15E-63 |
zinc ion binding | Pfam | molecular function | 1.1E-5 |
membrane | TIGRFAM | cellular component | 5.4E-195 |
integral component of membrane | Pfam | cellular component | 1.1E-5 |