Gene Card
Best human hits
HERC1; HERC2
Species
Unique Gene ID
Phmamm.g00001531
Gene Model ID
Phmamm.CG.MTP2014.S39.g01531
Location
S39:211745..256225
Transcript Models and Sequences
Phmamm.CG.MTP2014.S39.g01531.01.t
Phmamm.CG.MTP2014.S39.g01531.02.t
Phmamm.CG.MTP2014.S39.g01531.03.t
AHC0AAA16YN19
Plate: Plate_16_N19
AHC0AAA80YF17
Plate: Plate_80_F17
AHC0AAA101YF11
Plate: Plate_101_F11
AHC0AAA112YA04
Plate: Plate_112_A04
AHC0AAA128YK10
Plate: Plate_128_K10
AHC0AAA137YP11
Plate: Plate_137_P11
AHC0AAA98YG09
Plate: Plate_98_G09
AHC0AAA193YJ10
Plate: Plate_193_J10
AHC0AAA259YI17
Plate: Plate_259_I17
AHC0AAA98YI11
Plate: Plate_98_I11
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
WD40_repeat_dom | ProSiteProfiles | WD40-repeat-containing domain |
WD40_repeat | ProSiteProfiles | WD40 repeat |
SPRY_dom | Pfam | SPRY domain |
Reg_chr_condens | ProSiteProfiles | Regulator of chromosome condensation, RCC1 |
HECT_dom | SMART | HECT domain |
RCC1/BLIP-II | SUPERFAMILY | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
WD40_repeat_dom_sf | SUPERFAMILY | WD40-repeat-containing domain superfamily |
B30.2/SPRY | ProSiteProfiles | B30.2/SPRY domain |
HECT_dom | ProSiteProfiles | HECT domain |
Reg_chr_condens | ProSitePatterns | Regulator of chromosome condensation, RCC1 |
ConA-like_dom_sf | SUPERFAMILY | Concanavalin A-like lectin/glucanase domain superfamily |
WD40_repeat | SMART | WD40 repeat |
RCC1/BLIP-II | Gene3D | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
Hect_E3_ubiquitin_ligase | SUPERFAMILY | HECT, E3 ligase catalytic domain |
Reg_chr_condens | Pfam | Regulator of chromosome condensation, RCC1 |
Reg_chr_condens | PRINTS | Regulator of chromosome condensation, RCC1 |
WD40_repeat | Pfam | WD40 repeat |
Apc4_WD40_dom | Pfam | Anaphase-promoting complex subunit 4, WD40 domain |
SPRY_HERC1 | CDD | HERC1, SPRY domain |
HECT_dom | Pfam | HECT domain |
SPRY_dom | SMART | SPRY domain |
GO Term | Annotation Origin | Type |
---|---|---|
ubiquitin-protein transferase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrial inner membrane | Blast | cellular component |
Golgi apparatus | Orthology | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Blast | cellular component |
zinc ion binding | Blast | molecular function |
membrane | Orthology | cellular component |
protein ubiquitination | Orthology | biological process |
transferase activity | Orthology | molecular function |
neuron projection development | Orthology | biological process |
ubiquitin protein ligase binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
regulation of molecular function | Orthology | biological process |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
neuron differentiation | Orthology | biological process |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
brain development | Orthology | biological process |
nervous system process | Orthology | biological process |
cytoplasmic part | Blast | cellular component |
microtubule organizing center | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ubiquitin-protein transferase activity | Hs | molecular function |
guanyl-nucleotide exchange factor activity | Hs | molecular function |
ARF guanyl-nucleotide exchange factor activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
Golgi apparatus | Hs | cellular component |
cytosol | Hs | cellular component |
negative regulation of autophagy | Hs | biological process |
membrane | Hs | cellular component |
protein ubiquitination | Hs | biological process |
transferase activity | Hs | molecular function |
cerebellar Purkinje cell differentiation | Hs | biological process |
neuron projection development | Hs | biological process |
neuromuscular process controlling balance | Hs | biological process |
regulation of molecular function | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin-protein transferase activity | Hs | molecular function | 1537 | 0.0 |
guanyl-nucleotide exchange factor activity | Hs | molecular function | 1537 | 0.0 |
ARF guanyl-nucleotide exchange factor activity | Hs | molecular function | 1537 | 0.0 |
protein binding | Hs | molecular function | 1537 | 0.0 |
nucleus | Hs | cellular component | 597 | 9.01e-175 |
nucleoplasm | Hs | cellular component | 597 | 8.51e-171 |
cytoplasm | Hs | cellular component | 1537 | 0.0 |
mitochondrial inner membrane | Hs | cellular component | 597 | 8.51e-171 |
Golgi apparatus | Hs | cellular component | 1537 | 0.0 |
centriole | Hs | cellular component | 597 | 8.51e-171 |
cytosol | Hs | cellular component | 1537 | 0.0 |
cytoskeleton | Hs | cellular component | 597 | 8.51e-171 |
zinc ion binding | Hs | molecular function | 597 | 8.51e-171 |
membrane | Hs | cellular component | 1537 | 0.0 |
transferase activity | Hs | molecular function | 1537 | 0.0 |
ubiquitin protein ligase binding | Hs | molecular function | 597 | 8.51e-171 |
SUMO binding | Hs | molecular function | 597 | 8.51e-171 |
metal ion binding | Hs | molecular function | 597 | 8.51e-171 |
ubiquitin protein ligase activity | Hs | molecular function | 597 | 9.01e-175 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-protein transferase activity | SMART | molecular function | 2.7E-88 |
protein binding | SUPERFAMILY | molecular function | 4.27E-32 |