Gene Card
Best human hits
EARS2; EPRS; QARS
Species
Unique Gene ID
Phmamm.g00001655
Gene Model ID
Phmamm.CG.MTP2014.S42.g01655
Location
S42:291043..294358
Transcript Models and Sequences
AHC0AAA23YL23
Plate: Plate_23_L23
AHC0AAA61YN16
Plate: Plate_61_N16
AHC0AAA106YG02
Plate: Plate_106_G02
AHC0AAA106YI04
Plate: Plate_106_I04
AHC0AAA159YG06
Plate: Plate_159_G06
AHC0AAA239YL18
Plate: Plate_239_L18
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Glu-tRNA-ligase_bac/mito | TIGRFAM | Glutamate-tRNA ligase, bacterial/mitochondrial |
GluRS_core | CDD | Glutamyl-tRNA synthetase |
Rossmann-like_a/b/a_fold | Gene3D | Rossmann-like alpha/beta/alpha sandwich fold |
aa-tRNA-synth_I_codon-bd_sub2 | Gene3D | Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 |
Glu/Gln-tRNA-synth | PRINTS | Glutamyl/glutaminyl-tRNA synthetase |
Glu/Gln-tRNA-synth_Ib_cat-dom | Pfam | Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain |
aa-tRNA-synth_I_codon-bd | SUPERFAMILY | Aminoacyl-tRNA synthetase, class I, anticodon-binding |
Glu-tRNA-ligase_bac/mito | Hamap | Glutamate-tRNA ligase, bacterial/mitochondrial |
aa-tRNA-synth_I_CS | ProSitePatterns | Aminoacyl-tRNA synthetase, class I, conserved site |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
catalytic activity | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Blast | cellular component |
zinc ion binding | Orthology | molecular function |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
ligase activity | Orthology | molecular function |
protein kinase binding | Blast | molecular function |
macromolecular complex | Blast | cellular component |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
metal ion binding | Blast | molecular function |
RNA metabolic process | Orthology | biological process |
enzyme regulator activity | Blast | molecular function |
protein kinase activity | Blast | molecular function |
intracellular part | Blast | cellular component |
enzyme binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
tRNA binding | Hs | molecular function |
nucleotide binding | Hs | molecular function |
RNA binding | Hs | molecular function |
aminoacyl-tRNA ligase activity | Hs | molecular function |
glutamate-tRNA ligase activity | Hs | molecular function |
ATP binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
translation | Hs | biological process |
tRNA aminoacylation for protein translation | Hs | biological process |
glutamyl-tRNA aminoacylation | Hs | biological process |
zinc ion binding | Hs | molecular function |
ligase activity | Hs | molecular function |
tRNA aminoacylation | Hs | biological process |
glutamate-tRNA(Gln) ligase activity | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
tRNA binding | Hs | molecular function | 395 | 7.15e-132 |
nucleotide binding | Hs | molecular function | 395 | 7.15e-132 |
RNA binding | Hs | molecular function | 395 | 7.15e-132 |
catalytic activity | Hs | molecular function | 55.5 | 8.21e-08 |
aminoacyl-tRNA ligase activity | Hs | molecular function | 395 | 7.15e-132 |
glutamate-tRNA ligase activity | Hs | molecular function | 395 | 7.15e-132 |
glutamine-tRNA ligase activity | Hs | molecular function | 57.4 | 1.50e-08 |
proline-tRNA ligase activity | Hs | molecular function | 55.5 | 8.21e-08 |
protein kinase inhibitor activity | Hs | molecular function | 57.4 | 1.50e-08 |
protein binding | Hs | molecular function | 57.4 | 1.50e-08 |
ATP binding | Hs | molecular function | 395 | 7.15e-132 |
cytoplasm | Hs | cellular component | 395 | 7.15e-132 |
mitochondrion | Hs | cellular component | 395 | 7.15e-132 |
mitochondrial matrix | Hs | cellular component | 395 | 7.15e-132 |
cytosol | Hs | cellular component | 57.4 | 1.50e-08 |
zinc ion binding | Hs | molecular function | 395 | 7.15e-132 |
membrane | Hs | cellular component | 57.4 | 1.50e-08 |
integral component of membrane | Hs | cellular component | 57.4 | 1.50e-08 |
ligase activity | Hs | molecular function | 395 | 7.15e-132 |
aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component | 57.4 | 1.50e-08 |
protein kinase binding | Hs | molecular function | 57.4 | 1.50e-08 |
intracellular ribonucleoprotein complex | Hs | cellular component | 55.5 | 8.21e-08 |
macromolecular complex | Hs | cellular component | 57.4 | 1.50e-08 |
RNA stem-loop binding | Hs | molecular function | 55.5 | 8.21e-08 |
identical protein binding | Hs | molecular function | 55.5 | 8.21e-08 |
protein homodimerization activity | Hs | molecular function | 55.5 | 8.21e-08 |
metal ion binding | Hs | molecular function | 55.5 | 8.21e-08 |
glutamate-tRNA(Gln) ligase activity | Hs | molecular function | 395 | 7.15e-132 |
GTPase binding | Hs | molecular function | 55.5 | 8.21e-08 |
GAIT complex | Hs | cellular component | 55.5 | 8.21e-08 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
tRNA binding | SUPERFAMILY | molecular function | 8.24E-15 |
nucleotide binding | TIGRFAM | molecular function | 8.8E-130 |
aminoacyl-tRNA ligase activity | Pfam | molecular function | 1.1E-92 |
glutamate-tRNA ligase activity | TIGRFAM | molecular function | 8.8E-130 |
ATP binding | TIGRFAM | molecular function | 8.8E-130 |
cytoplasm | TIGRFAM | cellular component | 8.8E-130 |
tRNA aminoacylation for protein translation | ProSitePatterns | biological process | |
glutamyl-tRNA aminoacylation | TIGRFAM | biological process | 8.8E-130 |
zinc ion binding | CDD | molecular function | 7.21197E-112 |
tRNA aminoacylation | Pfam | biological process | 1.1E-92 |