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GENE CARD

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Gene Card

Best human hits

SIRT2; SIRT3

Species

P.mammillata

Unique Gene ID

Phmamm.g00004173

Gene Model ID

Phmamm.CG.MTP2014.S146.g04173

Location

S146:129522..137169

External Database Gene Card

External database links

No result

Collections

Genoscope Yasuo Villefranche

3 results

AHC0AAA8YL03

Plate: Plate_8_L03

AHC0AAA106YL15

Plate: Plate_106_L15

AHC0AAA106YL13

Plate: Plate_106_L13

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
Ssirtuin_cat_dom ProSiteProfiles Sirtuin family, catalytic core domain
Sirtuin Pfam Sirtuin family
Sirtuin_cat_small_dom_sf Gene3D Sirtuin, catalytic core small domain superfamily
DHS-like_NAD/FAD-binding_dom SUPERFAMILY DHS-like NAD/FAD-binding domain superfamily

GOSlim

51 results

GO Term Annotation Origin Type
chromatin binding Blast molecular function
protein binding Orthology molecular function
nucleus Blast cellular component
nucleolus Blast cellular component
cytoplasm Blast cellular component
mitochondrion Orthology cellular component
mitochondrial matrix Orthology cellular component
centrosome Blast cellular component
microtubule organizing center Blast cellular component
cytosol Blast cellular component
cytoskeleton Blast cellular component
microtubule Blast cellular component
plasma membrane Blast cellular component
transcription factor binding Blast molecular function
zinc ion binding Orthology molecular function
membrane Blast cellular component
hydrolase activity Orthology molecular function
enzyme binding Orthology molecular function
midbody Blast cellular component
macromolecular complex Orthology cellular component
cell projection Blast cellular component
myelin sheath Blast cellular component
sequence-specific DNA binding Orthology molecular function
metal ion binding Orthology molecular function
perinuclear region of cytoplasm Blast cellular component
transferase activity Orthology molecular function
cellular protein modification process Orthology biological process
organelle organization Orthology biological process
developmental process Orthology biological process
oxidation-reduction process Orthology biological process
cellular metabolic process Orthology biological process
protein transport Orthology biological process
cell-cell signaling Orthology biological process
intracellular signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
protein phosphorylation Orthology biological process
anion binding Orthology molecular function
nucleotide binding Orthology molecular function
coenzyme binding Orthology molecular function
intracellular organelle part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
nucleoplasm part Blast cellular component
nuclear lumen Blast cellular component
cytoplasmic part Blast cellular component
cytoskeletal part Blast cellular component
microtubule cytoskeleton Blast cellular component
cell projection part Blast cellular component
axon Blast cellular component
cell junction Blast cellular component
neuronal cell body Blast cellular component
plasma membrane region Blast cellular component

GO (Orthology)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
NAD+ ADP-ribosyltransferase activity Hs molecular function
protein binding Hs molecular function
mitochondrion Hs cellular component
mitochondrial matrix Hs cellular component
protein ADP-ribosylation Hs biological process
protein deacetylation Hs biological process
mitochondrion organization Hs biological process
aging Hs biological process
zinc ion binding Hs molecular function
aerobic respiration Hs biological process
histone deacetylation Hs biological process
hydrolase activity Hs molecular function
NAD-dependent histone deacetylase activity Hs molecular function
enzyme binding Hs molecular function
positive regulation of insulin secretion Hs biological process
macromolecular complex Hs cellular component
NAD-dependent protein deacetylase activity Hs molecular function
sequence-specific DNA binding Hs molecular function
metal ion binding Hs molecular function
negative regulation of ERK1 and ERK2 cascade Hs biological process
NAD+ binding Hs molecular function
negative regulation of reactive oxygen species metabolic process Hs biological process

GO (Blast)

52 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
chromosome, telomeric region Hs cellular component 276 2.11e-87
chromatin binding Hs molecular function 276 2.11e-87
NAD+ ADP-ribosyltransferase activity Hs molecular function 343 5.91e-113
histone deacetylase activity Hs molecular function 276 2.11e-87
protein binding Hs molecular function 343 5.91e-113
nucleus Hs cellular component 276 2.11e-87
chromatin silencing complex Hs cellular component 276 2.11e-87
chromosome Hs cellular component 276 2.11e-87
nuclear heterochromatin Hs cellular component 276 2.11e-87
nucleolus Hs cellular component 276 2.11e-87
cytoplasm Hs cellular component 276 2.11e-87
mitochondrion Hs cellular component 343 5.91e-113
mitochondrial matrix Hs cellular component 343 5.91e-113
centrosome Hs cellular component 276 2.11e-87
centriole Hs cellular component 276 2.11e-87
microtubule organizing center Hs cellular component 276 2.11e-87
spindle Hs cellular component 276 2.11e-87
cytosol Hs cellular component 276 2.11e-87
cytoskeleton Hs cellular component 276 2.11e-87
microtubule Hs cellular component 276 2.11e-87
plasma membrane Hs cellular component 276 2.11e-87
transcription factor binding Hs molecular function 276 2.11e-87
zinc ion binding Hs molecular function 343 5.91e-113
membrane Hs cellular component 276 2.11e-87
hydrolase activity Hs molecular function 343 5.91e-113
NAD-dependent histone deacetylase activity Hs molecular function 343 5.91e-113
enzyme binding Hs molecular function 343 5.91e-113
growth cone Hs cellular component 276 2.11e-87
midbody Hs cellular component 276 2.11e-87
macromolecular complex Hs cellular component 343 5.91e-113
paranodal junction Hs cellular component 276 2.11e-87
paranode region of axon Hs cellular component 276 2.11e-87
protein deacetylase activity Hs molecular function 276 2.11e-87
NAD-dependent protein deacetylase activity Hs molecular function 343 5.91e-113
histone acetyltransferase binding Hs molecular function 276 2.11e-87
histone deacetylase binding Hs molecular function 276 2.11e-87
tubulin deacetylase activity Hs molecular function 276 2.11e-87
cell projection Hs cellular component 276 2.11e-87
ubiquitin binding Hs molecular function 276 2.11e-87
perikaryon Hs cellular component 276 2.11e-87
myelin sheath Hs cellular component 276 2.11e-87
lateral loop Hs cellular component 276 2.11e-87
Schmidt-Lanterman incisure Hs cellular component 276 2.11e-87
sequence-specific DNA binding Hs molecular function 343 5.91e-113
juxtaparanode region of axon Hs cellular component 276 2.11e-87
metal ion binding Hs molecular function 343 5.91e-113
NAD-dependent histone deacetylase activity (H4-K16 specific) Hs molecular function 276 2.11e-87
perinuclear region of cytoplasm Hs cellular component 276 2.11e-87
NAD+ binding Hs molecular function 343 5.91e-113
mitotic spindle Hs cellular component 276 2.11e-87
meiotic spindle Hs cellular component 276 2.11e-87
glial cell projection Hs cellular component 276 2.11e-87

GO (InterProScan)

1 result

GO Term Analysis Type e-value
NAD+ binding Pfam molecular function 7.2E-55