Gene Card
Best human hits
HSD3B1; HSD3B2; HSD3B7
Species
Unique Gene ID
Phmamm.g00004427
Gene Model ID
Phmamm.CG.MTP2014.S159.g04427
Location
S159:6415..10206
Transcript Models and Sequences
AHC0AAA11YO01
Plate: Plate_11_O01
AHC0AAA18YO24
Plate: Plate_18_O24
AHC0AAA24YH14
Plate: Plate_24_H14
AHC0AAA24YP03
Plate: Plate_24_P03
AHC0AAA35YD13
Plate: Plate_35_D13
AHC0AAA36YF06
Plate: Plate_36_F06
AHC0AAA36YI05
Plate: Plate_36_I05
AHC0AAA63YH23
Plate: Plate_63_H23
AHC0AAA66YH08
Plate: Plate_66_H08
AHC0AAA68YF01
Plate: Plate_68_F01
AHC0AAA100YK16
Plate: Plate_100_K16
AHC0AAA112YM01
Plate: Plate_112_M01
AHC0AAA115YC19
Plate: Plate_115_C19
AHC0AAA120YP24
Plate: Plate_120_P24
AHC0AAA124YI24
Plate: Plate_124_I24
AHC0AAA126YG19
Plate: Plate_126_G19
AHC0AAA134YJ09
Plate: Plate_134_J09
AHC0AAA135YI16
Plate: Plate_135_I16
AHC0AAA151YH05
Plate: Plate_151_H05
AHC0AAA152YG11
Plate: Plate_152_G11
AHC0AAA152YO16
Plate: Plate_152_O16
AHC0AAA87YK07
Plate: Plate_87_K07
AHC0AAA98YK20
Plate: Plate_98_K20
AHC0AAA120YP22
Plate: Plate_120_P22
AHC0AAA159YC01
Plate: Plate_159_C01
AHC0AAA165YI06
Plate: Plate_165_I06
AHC0AAA174YH16
Plate: Plate_174_H16
AHC0AAA206YE17
Plate: Plate_206_E17
AHC0AAA220YI10
Plate: Plate_220_I10
AHC0AAA230YM10
Plate: Plate_230_M10
AHC0AAA239YE22
Plate: Plate_239_E22
AHC0AAA246YE22
Plate: Plate_246_E22
AHC0AAA253YD20
Plate: Plate_253_D20
AHC0AAA257YH19
Plate: Plate_257_H19
AHC0AAA98YK18
Plate: Plate_98_K18
n/a
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IPR Term | Analysis | Definition |
---|---|---|
3Beta_OHSteriod_DH/Estase | Pfam | 3-beta hydroxysteroid dehydrogenase/isomerase |
NAD(P)-bd_dom_sf | SUPERFAMILY | NAD(P)-binding domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
catalytic activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
mitochondrion | Blast | cellular component |
mitochondrial inner membrane | Blast | cellular component |
endoplasmic reticulum | Orthology | cellular component |
endoplasmic reticulum membrane | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
mitochondrial membrane | Blast | cellular component |
oxidation-reduction process | Orthology | biological process |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
cellular biosynthetic process | Orthology | biological process |
cell migration | Orthology | biological process |
immune system process | Orthology | biological process |
chemotaxis | Orthology | biological process |
mitochondrial envelope | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
3-beta-hydroxy-delta5-steroid dehydrogenase activity | Hs | molecular function |
protein binding | Hs | molecular function |
endoplasmic reticulum | Hs | cellular component |
endoplasmic reticulum membrane | Hs | cellular component |
lipid droplet | Hs | cellular component |
steroid biosynthetic process | Hs | biological process |
bile acid biosynthetic process | Hs | biological process |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
oxidoreductase activity | Hs | molecular function |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Hs | molecular function |
B cell chemotaxis | Hs | biological process |
cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity | Hs | molecular function |
oxidation-reduction process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
catalytic activity | Hs | molecular function | 146 | 7.30e-41 |
3-beta-hydroxy-delta5-steroid dehydrogenase activity | Hs | molecular function | 164 | 2.12e-47 |
steroid delta-isomerase activity | Hs | molecular function | 146 | 7.30e-41 |
protein binding | Hs | molecular function | 164 | 2.12e-47 |
mitochondrion | Hs | cellular component | 146 | 7.30e-41 |
mitochondrial inner membrane | Hs | cellular component | 146 | 7.30e-41 |
mitochondrial intermembrane space | Hs | cellular component | 146 | 7.30e-41 |
endoplasmic reticulum | Hs | cellular component | 164 | 2.12e-47 |
endoplasmic reticulum membrane | Hs | cellular component | 164 | 2.12e-47 |
lipid droplet | Hs | cellular component | 164 | 2.12e-47 |
membrane | Hs | cellular component | 164 | 2.12e-47 |
integral component of membrane | Hs | cellular component | 164 | 2.12e-47 |
oxidoreductase activity | Hs | molecular function | 164 | 2.12e-47 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Hs | molecular function | 164 | 2.12e-47 |
isomerase activity | Hs | molecular function | 146 | 7.30e-41 |
smooth endoplasmic reticulum membrane | Hs | cellular component | 146 | 7.30e-41 |
mitochondrial membrane | Hs | cellular component | 146 | 7.30e-41 |
cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity | Hs | molecular function | 164 | 2.12e-47 |
cholesterol dehydrogenase activity | Hs | molecular function | 146 | 7.30e-41 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
3-beta-hydroxy-delta5-steroid dehydrogenase activity | Pfam | molecular function | 1.1E-63 |
steroid biosynthetic process | Pfam | biological process | 1.1E-63 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Pfam | molecular function | 1.1E-63 |
oxidation-reduction process | Pfam | biological process | 1.1E-63 |