Gene Card
Best human hits
MARK1; MARK2; MARK3
Species
Unique Gene ID
Phmamm.g00004582
Gene Model ID
Phmamm.CG.MTP2014.S166.g04582
Location
S166:72892..90433
Transcript Models and Sequences
Phmamm.CG.MTP2014.S166.g04582.01.t
Phmamm.CG.MTP2014.S166.g04582.02.t
Phmamm.CG.MTP2014.S166.g04582.03.t
Phmamm.CG.MTP2014.S166.g04582.04.t
AHC0AAA14YO14
Plate: Plate_14_O14
AHC0AAA54YA22
Plate: Plate_54_A22
AHC0AAA54YJ05
Plate: Plate_54_J05
AHC0AAA60YB04
Plate: Plate_60_B04
AHC0AAA66YJ08
Plate: Plate_66_J08
AHC0AAA77YG23
Plate: Plate_77_G23
AHC0AAA103YH18
Plate: Plate_103_H18
AHC0AAA131YK24
Plate: Plate_131_K24
AHC0AAA139YP11
Plate: Plate_139_P11
AHC0AAA152YC19
Plate: Plate_152_C19
AHC0AAA89YJ20
Plate: Plate_89_J20
AHC0AAA98YG21
Plate: Plate_98_G21
AHC0AAA166YP21
Plate: Plate_166_P21
AHC0AAA175YO12
Plate: Plate_175_O12
AHC0AAA179YM19
Plate: Plate_179_M19
AHC0AAA192YL09
Plate: Plate_192_L09
AHC0AAA193YF03
Plate: Plate_193_F03
AHC0AAA201YP14
Plate: Plate_201_P14
AHC0AAA223YK18
Plate: Plate_223_K18
AHC0AAA239YK14
Plate: Plate_239_K14
AHC0AAA268YH18
Plate: Plate_268_H18
AHC0AAA54YL07
Plate: Plate_54_L07
AHC0AAA98YI23
Plate: Plate_98_I23
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
MARK/par1 | PANTHER | Serine/threonine-protein kinase MARK/par1 |
Prot_kinase_dom | SMART | Protein kinase domain |
MARK3 | PANTHER | Serine/threonine-protein kinase MARK3 |
KA1_dom | ProSiteProfiles | Kinase associated domain 1 (KA1) |
UBA | SMART | Ubiquitin-associated domain |
UBA | ProSiteProfiles | Ubiquitin-associated domain |
Prot_kinase_dom | Pfam | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
KA1/Ssp2_C | SUPERFAMILY | KA1 domain/Ssp2, C-terminal |
KA1_dom | Pfam | Kinase associated domain 1 (KA1) |
UBA | Pfam | Ubiquitin-associated domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
magnesium ion binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
multicellular organism development | Orthology | biological process |
microtubule cytoskeleton | Orthology | cellular component |
membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
cell differentiation | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein autophosphorylation | Orthology | biological process |
metal ion binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
G1/S transition of mitotic cell cycle | Orthology | biological process |
G2/M transition of mitotic cell cycle | Orthology | biological process |
centrosome | Orthology | cellular component |
microtubule organizing center | Orthology | cellular component |
microtubule | Orthology | cellular component |
cell cycle | Orthology | biological process |
nervous system development | Orthology | biological process |
microtubule binding | Orthology | molecular function |
positive regulation of cell proliferation | Orthology | biological process |
cell projection organization | Orthology | biological process |
cell projection | Orthology | cellular component |
neuron projection | Orthology | cellular component |
positive regulation of programmed cell death | Orthology | biological process |
cell division | Orthology | biological process |
microtubule-based process | Orthology | biological process |
organelle organization | Orthology | biological process |
cell migration | Orthology | biological process |
generation of neurons | Orthology | biological process |
anion binding | Orthology | molecular function |
cytoskeletal part | Orthology | cellular component |
binding | Orthology | molecular function |
neuron projection development | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
plasma membrane part | Orthology | cellular component |
cellular process | Orthology | biological process |
enzyme activator activity | Orthology | molecular function |
protein kinase binding | Orthology | molecular function |
positive regulation of catalytic activity | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
axonogenesis | Orthology | biological process |
cytoplasmic part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
cell projection part | Orthology | cellular component |
plasma membrane region | Orthology | cellular component |
tubulin binding | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
MAPK cascade | Hs | biological process |
nucleotide binding | Hs | molecular function |
microtubule cytoskeleton organization | Hs | biological process |
magnesium ion binding | Hs | molecular function |
autophagy of mitochondrion | Hs | biological process |
neuron migration | Hs | biological process |
phosphatidylserine binding | Hs | molecular function |
RNA binding | Hs | molecular function |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
phosphatidylinositol-4,5-bisphosphate binding | Hs | molecular function |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
actin filament | Hs | cellular component |
plasma membrane | Hs | cellular component |
protein phosphorylation | Hs | biological process |
cytoskeleton organization | Hs | biological process |
multicellular organism development | Hs | biological process |
lipid binding | Hs | molecular function |
positive regulation of neuron projection development | Hs | biological process |
microtubule cytoskeleton | Hs | cellular component |
membrane | Hs | cellular component |
Wnt signaling pathway | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
lateral plasma membrane | Hs | cellular component |
transferase activity | Hs | molecular function |
peptidyl-threonine phosphorylation | Hs | biological process |
establishment of cell polarity | Hs | biological process |
cell differentiation | Hs | biological process |
protein kinase activator activity | Hs | molecular function |
activation of protein kinase activity | Hs | biological process |
negative regulation of hippo signaling | Hs | biological process |
intracellular signal transduction | Hs | biological process |
establishment or maintenance of epithelial cell apical/basal polarity | Hs | biological process |
cadherin binding | Hs | molecular function |
protein autophosphorylation | Hs | biological process |
metal ion binding | Hs | molecular function |
tau-protein kinase activity | Hs | molecular function |
regulation of axonogenesis | Hs | biological process |
regulation of cytoskeleton organization | Hs | biological process |
mitochondrion localization | Hs | biological process |
extracellular exosome | Hs | cellular component |
phosphatidic acid binding | Hs | molecular function |
microtubule bundle | Hs | cellular component |
G1/S transition of mitotic cell cycle | Hs | biological process |
G2/M transition of mitotic cell cycle | Hs | biological process |
gamma-tubulin complex | Hs | cellular component |
microtubule bundle formation | Hs | biological process |
centrosome | Hs | cellular component |
microtubule organizing center | Hs | cellular component |
microtubule | Hs | cellular component |
cell cycle | Hs | biological process |
nervous system development | Hs | biological process |
microtubule binding | Hs | molecular function |
positive regulation of cell proliferation | Hs | biological process |
cell projection organization | Hs | biological process |
ciliary basal body | Hs | cellular component |
cell projection | Hs | cellular component |
neuron projection | Hs | cellular component |
gamma-tubulin binding | Hs | molecular function |
positive regulation of programmed cell death | Hs | biological process |
ubiquitin binding | Hs | molecular function |
cell division | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 525 | 3.16e-179 |
magnesium ion binding | Hs | molecular function | 483 | 2.05e-162 |
phosphatidylserine binding | Hs | molecular function | 483 | 2.05e-162 |
RNA binding | Hs | molecular function | 466 | 4.21e-156 |
protein kinase activity | Hs | molecular function | 525 | 3.16e-179 |
protein serine/threonine kinase activity | Hs | molecular function | 525 | 3.16e-179 |
protein binding | Hs | molecular function | 525 | 3.16e-179 |
ATP binding | Hs | molecular function | 525 | 3.16e-179 |
phosphatidylinositol-4,5-bisphosphate binding | Hs | molecular function | 483 | 2.05e-162 |
nucleoplasm | Hs | cellular component | 466 | 4.21e-156 |
cytoplasm | Hs | cellular component | 483 | 2.05e-162 |
mitochondrion | Hs | cellular component | 466 | 4.21e-156 |
cytosol | Hs | cellular component | 525 | 3.16e-179 |
cytoskeleton | Hs | cellular component | 483 | 2.05e-162 |
actin filament | Hs | cellular component | 466 | 4.21e-156 |
plasma membrane | Hs | cellular component | 525 | 3.16e-179 |
lipid binding | Hs | molecular function | 483 | 2.05e-162 |
microtubule cytoskeleton | Hs | cellular component | 483 | 2.05e-162 |
membrane | Hs | cellular component | 525 | 3.16e-179 |
kinase activity | Hs | molecular function | 525 | 3.16e-179 |
lateral plasma membrane | Hs | cellular component | 466 | 4.21e-156 |
transferase activity | Hs | molecular function | 525 | 3.16e-179 |
protein kinase activator activity | Hs | molecular function | 466 | 4.21e-156 |
cadherin binding | Hs | molecular function | 466 | 4.21e-156 |
metal ion binding | Hs | molecular function | 483 | 2.05e-162 |
tau-protein kinase activity | Hs | molecular function | 483 | 2.05e-162 |
extracellular exosome | Hs | cellular component | 525 | 3.16e-179 |
phosphatidic acid binding | Hs | molecular function | 483 | 2.05e-162 |
microtubule bundle | Hs | cellular component | 466 | 4.21e-156 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
microtubule cytoskeleton organization | PANTHER | biological process | 2.3E-193 |
protein kinase activity | Pfam | molecular function | 1.9E-25 |
protein serine/threonine kinase activity | PANTHER | molecular function | 2.3E-193 |
ATP binding | Pfam | molecular function | 1.9E-25 |
protein phosphorylation | Pfam | biological process | 1.9E-25 |
establishment of cell polarity | PANTHER | biological process | 2.3E-193 |