IPR Term	Analysis	Definition
Nck-associated_protein-1	PANTHER	Nck-associated protein 1
Nck-associated_protein-1	Pfam	Nck-associated protein 1

GO Term	Annotation Origin	Type
GTPase activator activity	Orthology	molecular function
protein binding	Orthology	molecular function
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Orthology	cellular component
focal adhesion	Orthology	cellular component
apoptotic process	Orthology	biological process
chemotaxis	Orthology	biological process
central nervous system development	Orthology	biological process
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
lamellipodium	Orthology	cellular component
cell projection	Orthology	cellular component
negative regulation of apoptotic process	Orthology	biological process
positive regulation of GTPase activity	Orthology	biological process
macromolecular complex binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
plasma membrane region	Orthology	cellular component
cell leading edge	Orthology	cellular component
cell projection assembly	Orthology	biological process
small GTPase mediated signal transduction	Orthology	biological process
cellular process	Orthology	biological process
enzyme activator activity	Orthology	molecular function
protein kinase binding	Orthology	molecular function
protein kinase activity	Orthology	molecular function
cell migration	Orthology	biological process
immune system process	Orthology	biological process
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
endomembrane system	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
organelle organization	Orthology	biological process
cytoplasmic part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
cell projection membrane	Orthology	cellular component
cytoskeletal part	Orthology	cellular component
positive regulation of catalytic activity	Orthology	biological process
cell adhesion	Orthology	biological process
protein dephosphorylation	Orthology	biological process
phosphorylation	Orthology	biological process
animal organ development	Orthology	biological process
cell differentiation	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
enzyme binding	Orthology	molecular function
cell development	Orthology	biological process
immune response	Orthology	biological process
membrane organization	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
ruffle	Hs	cellular component
GTPase activator activity	Hs	molecular function
protein binding	Hs	molecular function
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
focal adhesion	Hs	cellular component
apoptotic process	Hs	biological process
chemotaxis	Hs	biological process
central nervous system development	Hs	biological process
positive regulation of lamellipodium assembly	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
viral process	Hs	biological process
Rac protein signal transduction	Hs	biological process
maintenance of cell polarity	Hs	biological process
lamellipodium	Hs	cellular component
protein kinase activator activity	Hs	molecular function
neutrophil chemotaxis	Hs	biological process
secretory granule membrane	Hs	cellular component
positive regulation of actin filament polymerization	Hs	biological process
cortical actin cytoskeleton organization	Hs	biological process
SCAR complex	Hs	cellular component
lamellipodium membrane	Hs	cellular component
filamentous actin	Hs	cellular component
activation of protein kinase activity	Hs	biological process
positive regulation of cell adhesion mediated by integrin	Hs	biological process
erythrocyte homeostasis	Hs	biological process
negative regulation of myosin-light-chain-phosphatase activity	Hs	biological process
positive regulation of phosphorylation	Hs	biological process
response to drug	Hs	biological process
cell projection	Hs	cellular component
T cell homeostasis	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
positive regulation of GTPase activity	Hs	biological process
macromolecular complex binding	Hs	molecular function
positive regulation of B cell differentiation	Hs	biological process
positive regulation of erythrocyte differentiation	Hs	biological process
vascular endothelial growth factor receptor signaling pathway	Hs	biological process
Rac GTPase binding	Hs	molecular function
erythrocyte development	Hs	biological process
B cell receptor signaling pathway	Hs	biological process
positive regulation of phagocytosis, engulfment	Hs	biological process
extracellular exosome	Hs	cellular component
positive regulation of neutrophil chemotaxis	Hs	biological process
ficolin-1-rich granule membrane	Hs	cellular component
positive regulation of Arp2/3 complex-mediated actin nucleation	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
ruffle	Hs	cellular component	900	0.0
GTPase activator activity	Hs	molecular function	729	0.0
protein binding	Hs	molecular function	900	0.0
cytoplasm	Hs	cellular component	729	0.0
cytosol	Hs	cellular component	900	0.0
plasma membrane	Hs	cellular component	900	0.0
integral component of plasma membrane	Hs	cellular component	729	0.0
focal adhesion	Hs	cellular component	900	0.0
membrane	Hs	cellular component	900	0.0
integral component of membrane	Hs	cellular component	900	0.0
lamellipodium	Hs	cellular component	900	0.0
protein kinase activator activity	Hs	molecular function	729	0.0
secretory granule membrane	Hs	cellular component	729	0.0
SCAR complex	Hs	cellular component	900	0.0
lamellipodium membrane	Hs	cellular component	900	0.0
filamentous actin	Hs	cellular component	900	0.0
cell projection	Hs	cellular component	900	0.0
macromolecular complex binding	Hs	molecular function	900	0.0
Rac GTPase binding	Hs	molecular function	900	0.0
extracellular exosome	Hs	cellular component	900	0.0
ficolin-1-rich granule membrane	Hs	cellular component	729	0.0