IPR Term	Analysis	Definition
AAA+_ATPase	SMART	AAA+ ATPase domain
Prot_ATP_ID_OB	Pfam	Proteasomal ATPase, OB/ID domain
P-loop_NTPase	SUPERFAMILY	P-loop containing nucleoside triphosphate hydrolase
ATPase_AAA_core	Pfam	ATPase, AAA-type, core
ATPase_AAA_CS	ProSitePatterns	ATPase, AAA-type, conserved site
26S_Psome_P45-like	TIGRFAM	26S proteasome regulatory subunit P45-like
PSMC3	PANTHER	26S Proteasome regulatory subunit 6A

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
protein polyubiquitination	Orthology	biological process
RNA binding	Blast	molecular function
receptor binding	Blast	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
extracellular region	Orthology	cellular component
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
transcription factor binding	Orthology	molecular function
membrane	Orthology	cellular component
hydrolase activity	Orthology	molecular function
cytoplasmic vesicle	Orthology	cellular component
identical protein binding	Orthology	molecular function
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transmembrane transport	Orthology	biological process
extracellular exosome	Blast	cellular component
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
postsynapse	Blast	cellular component
intracellular signal transduction	Orthology	biological process
protein phosphorylation	Orthology	biological process
intracellular part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
G2/M transition of mitotic cell cycle	Orthology	biological process
peptidase activity, acting on L-amino acid peptides	Orthology	molecular function
nucleoside-triphosphatase activity	Orthology	molecular function
protein metabolic process	Orthology	biological process
cellular response to stress	Orthology	biological process
response to organic substance	Orthology	biological process
proteolysis	Orthology	biological process
nuclear lumen	Orthology	cellular component
cytokine-mediated signaling pathway	Orthology	biological process
intracellular organelle part	Orthology	cellular component
endomembrane system	Orthology	cellular component
intracellular organelle lumen	Orthology	cellular component
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
cell surface receptor signaling pathway	Orthology	biological process
immune response	Orthology	biological process
mRNA catabolic process	Orthology	biological process
cellular protein modification process	Orthology	biological process
transcription initiation from RNA polymerase II promoter	Orthology	biological process
cell-cell signaling	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
animal organ development	Orthology	biological process
immune system process	Orthology	biological process
cell differentiation	Orthology	biological process
extracellular space	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
MAPK cascade	Hs	biological process
nucleotide binding	Hs	molecular function
protein polyubiquitination	Hs	biological process
proteasome complex	Hs	cellular component
P-body	Hs	cellular component
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
extracellular region	Hs	cellular component
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
proteasome regulatory particle, base subcomplex	Hs	cellular component
negative regulation of G2/M transition of mitotic cell cycle	Hs	biological process
membrane	Hs	cellular component
viral process	Hs	biological process
protein deubiquitination	Hs	biological process
hydrolase activity	Hs	molecular function
ATPase activity	Hs	molecular function
TBP-class protein binding	Hs	molecular function
proteasome accessory complex	Hs	cellular component
protein catabolic process	Hs	biological process
ubiquitin-dependent ERAD pathway	Hs	biological process
anaphase-promoting complex-dependent catabolic process	Hs	biological process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Hs	biological process
nuclear proteasome complex	Hs	cellular component
cytosolic proteasome complex	Hs	cellular component
tumor necrosis factor-mediated signaling pathway	Hs	biological process
secretory granule lumen	Hs	cellular component
proteasome-activating ATPase activity	Hs	molecular function
NIK/NF-kappaB signaling	Hs	biological process
Fc-epsilon receptor signaling pathway	Hs	biological process
identical protein binding	Hs	molecular function
proteasome-mediated ubiquitin-dependent protein catabolic process	Hs	biological process
regulation of mRNA stability	Hs	biological process
post-translational protein modification	Hs	biological process
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
T cell receptor signaling pathway	Hs	biological process
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Hs	biological process
transmembrane transport	Hs	biological process
Wnt signaling pathway, planar cell polarity pathway	Hs	biological process
interleukin-1-mediated signaling pathway	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process
positive regulation of proteasomal protein catabolic process	Hs	biological process
regulation of hematopoietic stem cell differentiation	Hs	biological process
ficolin-1-rich granule lumen	Hs	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	758	0.0
proteasome complex	Hs	cellular component	758	0.0
P-body	Hs	cellular component	758	0.0
RNA binding	Hs	molecular function	350	1.09e-117
receptor binding	Hs	molecular function	327	9.07e-109
protein binding	Hs	molecular function	758	0.0
ATP binding	Hs	molecular function	758	0.0
extracellular region	Hs	cellular component	758	0.0
nucleus	Hs	cellular component	758	0.0
nucleoplasm	Hs	cellular component	758	0.0
cytoplasm	Hs	cellular component	758	0.0
cytosol	Hs	cellular component	758	0.0
proteasome regulatory particle	Hs	cellular component	350	1.09e-117
transcription factor binding	Hs	molecular function	327	9.07e-109
proteasome regulatory particle, base subcomplex	Hs	cellular component	758	0.0
membrane	Hs	cellular component	758	0.0
inclusion body	Hs	cellular component	327	9.07e-109
hydrolase activity	Hs	molecular function	758	0.0
ATPase activity	Hs	molecular function	758	0.0
TBP-class protein binding	Hs	molecular function	758	0.0
proteasome accessory complex	Hs	cellular component	758	0.0
cytoplasmic vesicle	Hs	cellular component	327	9.07e-109
thyrotropin-releasing hormone receptor binding	Hs	molecular function	327	9.07e-109
nuclear proteasome complex	Hs	cellular component	758	0.0
cytosolic proteasome complex	Hs	cellular component	758	0.0
secretory granule lumen	Hs	cellular component	758	0.0
proteasome-activating ATPase activity	Hs	molecular function	758	0.0
identical protein binding	Hs	molecular function	758	0.0
extracellular exosome	Hs	cellular component	327	9.07e-109
blood microparticle	Hs	cellular component	327	9.07e-109
postsynapse	Hs	cellular component	327	9.07e-109
ficolin-1-rich granule lumen	Hs	cellular component	758	0.0

GO Term	Analysis	Type	e-value
ATP binding	Pfam	molecular function	8.5E-41
cytoplasm	TIGRFAM	cellular component	6.0E-124
hydrolase activity	TIGRFAM	molecular function	6.0E-124
protein catabolic process	TIGRFAM	biological process	6.0E-124
proteasome-activating ATPase activity	PANTHER	molecular function	6.4E-223