IPR Term	Analysis	Definition
Tyr_kinase_AS	ProSitePatterns	Tyrosine-protein kinase, active site
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Prot_kinase_dom	SMART	Protein kinase domain
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
Prot_kinase_dom	Pfam	Protein kinase domain

GO Term	Annotation Origin	Type
Golgi membrane	Blast	cellular component
nucleotide binding	Orthology	molecular function
magnesium ion binding	Orthology	molecular function
protein kinase activity	Orthology	molecular function
protein serine/threonine kinase activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
extracellular region	Blast	cellular component
intracellular	Blast	cellular component
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
mitochondrial inner membrane	Orthology	cellular component
Golgi apparatus	Blast	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Blast	cellular component
protein phosphorylation	Orthology	biological process
response to oxidative stress	Orthology	biological process
positive regulation of gene expression	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
protein ubiquitination	Orthology	biological process
transferase activity	Orthology	molecular function
lamellipodium	Blast	cellular component
axon	Orthology	cellular component
midbody	Blast	cellular component
ubiquitin protein ligase binding	Orthology	molecular function
intracellular signal transduction	Orthology	biological process
cell projection	Orthology	cellular component
neuronal cell body	Blast	cellular component
negative regulation of apoptotic process	Orthology	biological process
cell body	Orthology	cellular component
metal ion binding	Orthology	molecular function
perinuclear region of cytoplasm	Orthology	cellular component
intracellular part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
organelle organization	Orthology	biological process
intracellular organelle part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
enzyme binding	Orthology	molecular function
transmembrane transport	Orthology	biological process
monovalent inorganic cation transport	Orthology	biological process
regulation of cellular metabolic process	Orthology	biological process
response to stress	Orthology	biological process
whole membrane	Orthology	cellular component
mitochondrial membrane	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
membrane part	Orthology	cellular component
mitochondrial envelope	Orthology	cellular component
intracellular organelle lumen	Orthology	cellular component
proteolysis	Orthology	biological process
peptidase activity	Orthology	molecular function
positive regulation of hydrolase activity	Orthology	biological process
enzyme activator activity	Orthology	molecular function
oxidation-reduction process	Orthology	biological process
cellular metabolic process	Orthology	biological process
cell projection part	Orthology	cellular component
chemical synaptic transmission	Orthology	biological process
cellular response to stress	Orthology	biological process
protein dephosphorylation	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
protein kinase binding	Orthology	molecular function
regulation of apoptotic process	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
positive regulation of catalytic activity	Orthology	biological process
ubiquitin-protein transferase activity	Orthology	molecular function
response to hypoxia	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
positive regulation of apoptotic process	Orthology	biological process
neuron part	Orthology	cellular component
plasma membrane region	Orthology	cellular component
negative regulation of cell death	Orthology	biological process
ubiquitin-like protein transferase activity	Orthology	molecular function
ligase activity	Orthology	molecular function
peptidase activity, acting on L-amino acid peptides	Orthology	molecular function
phosphate-containing compound metabolic process	Orthology	biological process
cell leading edge	Blast	cellular component
cytoplasmic part	Blast	cellular component
microtubule organizing center	Blast	cellular component
Golgi apparatus part	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
endomembrane system	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
ubiquitin ligase complex	Hs	cellular component
nucleotide binding	Hs	molecular function
magnesium ion binding	Hs	molecular function
autophagy of mitochondrion	Hs	biological process
chromatin	Hs	cellular component
positive regulation of protein phosphorylation	Hs	biological process
protease binding	Hs	molecular function
regulation of oxidative phosphorylation	Hs	biological process
response to ischemia	Hs	biological process
protein kinase activity	Hs	molecular function
protein serine/threonine kinase activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
mitochondrial outer membrane	Hs	cellular component
mitochondrial outer membrane translocase complex	Hs	cellular component
mitochondrial inner membrane	Hs	cellular component
mitochondrial intermembrane space	Hs	cellular component
cytosol	Hs	cellular component
cytoskeleton	Hs	cellular component
protein phosphorylation	Hs	biological process
ubiquitin-dependent protein catabolic process	Hs	biological process
autophagy	Hs	biological process
response to oxidative stress	Hs	biological process
mitochondrion organization	Hs	biological process
regulation of hydrogen peroxide metabolic process	Hs	biological process
negative regulation of gene expression	Hs	biological process
regulation of mitochondrion organization	Hs	biological process
calcium-dependent protein kinase activity	Hs	molecular function
positive regulation of peptidase activity	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
macroautophagy	Hs	biological process
positive regulation of macroautophagy	Hs	biological process
negative regulation of macroautophagy	Hs	biological process
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
peptidase activator activity	Hs	molecular function
protein ubiquitination	Hs	biological process
transferase activity	Hs	molecular function
peptidyl-serine phosphorylation	Hs	biological process
respiratory electron transport chain	Hs	biological process
axon	Hs	cellular component
growth cone	Hs	cellular component
integral component of mitochondrial outer membrane	Hs	cellular component
regulation of protein ubiquitination	Hs	biological process
positive regulation of protein ubiquitination	Hs	biological process
ubiquitin protein ligase binding	Hs	molecular function
TORC2 complex	Hs	cellular component
positive regulation of synaptic transmission, dopaminergic	Hs	biological process
positive regulation of peptidyl-serine phosphorylation	Hs	biological process
cellular response to oxidative stress	Hs	biological process
positive regulation of protein dephosphorylation	Hs	biological process
intracellular signal transduction	Hs	biological process
TORC2 signaling	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
protein kinase B binding	Hs	molecular function
regulation of neuron apoptotic process	Hs	biological process
negative regulation of neuron apoptotic process	Hs	biological process
cell body	Hs	cellular component
positive regulation of translation	Hs	biological process
negative regulation of JNK cascade	Hs	biological process
metal ion binding	Hs	molecular function
perinuclear region of cytoplasm	Hs	cellular component
protein stabilization	Hs	biological process
positive regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
positive regulation of ubiquitin-protein transferase activity	Hs	biological process
regulation of mitochondrial membrane potential	Hs	biological process
positive regulation of protein kinase B signaling	Hs	biological process
C3HC4-type RING finger domain binding	Hs	molecular function
regulation of proteasomal protein catabolic process	Hs	biological process
cellular response to hypoxia	Hs	biological process
positive regulation of mitochondrial fission	Hs	biological process
positive regulation of release of cytochrome c from mitochondria	Hs	biological process
cellular response to toxic substance	Hs	biological process
Lewy body	Hs	cellular component
astrocyte projection	Hs	cellular component
regulation of cellular response to oxidative stress	Hs	biological process
negative regulation of neuron death	Hs	biological process
negative regulation of autophagosome assembly	Hs	biological process
regulation of autophagy of mitochondrion	Hs	biological process
negative regulation of autophagy of mitochondrion	Hs	biological process
negative regulation of oxidative stress-induced neuron death	Hs	biological process
regulation of reactive oxygen species metabolic process	Hs	biological process
negative regulation of reactive oxygen species metabolic process	Hs	biological process
positive regulation of ATP biosynthetic process	Hs	biological process
negative regulation of intrinsic apoptotic signaling pathway	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
Golgi membrane	Hs	cellular component	63.5	2.14e-10
ubiquitin ligase complex	Hs	cellular component	125	7.86e-31
nucleotide binding	Hs	molecular function	125	7.86e-31
magnesium ion binding	Hs	molecular function	125	7.86e-31
chromatin	Hs	cellular component	125	7.86e-31
ruffle	Hs	cellular component	63.5	2.14e-10
protease binding	Hs	molecular function	125	7.86e-31
protein kinase activity	Hs	molecular function	125	7.86e-31
protein serine/threonine kinase activity	Hs	molecular function	125	7.86e-31
protein binding	Hs	molecular function	125	7.86e-31
ATP binding	Hs	molecular function	125	7.86e-31
extracellular region	Hs	cellular component	63.5	2.14e-10
intracellular	Hs	cellular component	63.5	2.14e-10
nucleus	Hs	cellular component	125	7.86e-31
cytoplasm	Hs	cellular component	125	7.86e-31
mitochondrion	Hs	cellular component	125	7.86e-31
mitochondrial outer membrane	Hs	cellular component	125	7.86e-31
mitochondrial outer membrane translocase complex	Hs	cellular component	125	7.86e-31
mitochondrial inner membrane	Hs	cellular component	125	7.86e-31
mitochondrial intermembrane space	Hs	cellular component	125	7.86e-31
Golgi apparatus	Hs	cellular component	63.5	2.14e-10
centriole	Hs	cellular component	63.5	2.14e-10
cytosol	Hs	cellular component	125	7.86e-31
cytoskeleton	Hs	cellular component	125	7.86e-31
plasma membrane	Hs	cellular component	63.5	2.14e-10
calcium-dependent protein kinase activity	Hs	molecular function	125	7.86e-31
membrane	Hs	cellular component	125	7.86e-31
integral component of membrane	Hs	cellular component	125	7.86e-31
kinase activity	Hs	molecular function	125	7.86e-31
peptidase activator activity	Hs	molecular function	125	7.86e-31
transferase activity	Hs	molecular function	125	7.86e-31
Rho GTPase binding	Hs	molecular function	63.5	2.14e-10
GTP-Rho binding	Hs	molecular function	63.5	2.14e-10
SH3 domain binding	Hs	molecular function	62.8	3.95e-10
lamellipodium	Hs	cellular component	63.5	2.14e-10
PDZ domain binding	Hs	molecular function	62.8	3.95e-10
axon	Hs	cellular component	125	7.86e-31
growth cone	Hs	cellular component	125	7.86e-31
midbody	Hs	cellular component	62.8	3.95e-10
integral component of mitochondrial outer membrane	Hs	cellular component	125	7.86e-31
ubiquitin protein ligase binding	Hs	molecular function	125	7.86e-31
TORC2 complex	Hs	cellular component	125	7.86e-31
Golgi cisterna	Hs	cellular component	62.8	3.95e-10
bleb	Hs	cellular component	63.5	2.14e-10
cleavage furrow	Hs	cellular component	62.8	3.95e-10
secretory granule lumen	Hs	cellular component	63.5	2.14e-10
cell projection	Hs	cellular component	63.5	2.14e-10
neuronal cell body	Hs	cellular component	62.8	3.95e-10
protein kinase B binding	Hs	molecular function	125	7.86e-31
cell body	Hs	cellular component	125	7.86e-31
metal ion binding	Hs	molecular function	125	7.86e-31
perinuclear region of cytoplasm	Hs	cellular component	125	7.86e-31
C3HC4-type RING finger domain binding	Hs	molecular function	125	7.86e-31
scaffold protein binding	Hs	molecular function	62.8	3.95e-10
Lewy body	Hs	cellular component	125	7.86e-31
astrocyte projection	Hs	cellular component	125	7.86e-31
amyloid-beta complex	Hs	cellular component	63.5	2.14e-10

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	5.4E-18
ATP binding	Pfam	molecular function	5.4E-18
protein phosphorylation	Pfam	biological process	5.4E-18