IPR Term	Analysis	Definition
THDP-binding	SUPERFAMILY	Thiamin diphosphate-binding fold
DH_E1	Pfam	Dehydrogenase, E1 component
2oxoglutarate_DH_E1	PANTHER	2-oxoglutarate dehydrogenase E1 component
KGD_C	Pfam	Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
Transketolase-like_Pyr-bd	SMART	Transketolase-like, pyrimidine-binding domain
Transketolase-like_Pyr-bd	Pfam	Transketolase-like, pyrimidine-binding domain
2oxoglutarate_DH_E1	PIRSF	2-oxoglutarate dehydrogenase E1 component

GO Term	Annotation Origin	Type
protein binding	Blast	molecular function
nucleus	Blast	cellular component
mitochondrion	Orthology	cellular component
mitochondrial matrix	Orthology	cellular component
metabolic process	Orthology	biological process
mitochondrial membrane	Blast	cellular component
metal ion binding	Blast	molecular function
oxidation-reduction process	Orthology	biological process
animal organ development	Orthology	biological process
immune system process	Orthology	biological process
cell differentiation	Orthology	biological process
catalytic activity	Orthology	molecular function
cellular metabolic process	Orthology	biological process
nucleobase-containing compound metabolic process	Orthology	biological process
kinase activity	Orthology	molecular function
cation binding	Orthology	molecular function
small molecule binding	Orthology	molecular function
anion binding	Orthology	molecular function
heterocyclic compound binding	Orthology	molecular function
organic cyclic compound binding	Orthology	molecular function
coenzyme binding	Orthology	molecular function
cytoplasmic part	Orthology	cellular component
macromolecular complex	Orthology	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
hematopoietic progenitor cell differentiation	Hs	biological process
oxoglutarate dehydrogenase (succinyl-transferring) activity	Hs	molecular function
mitochondrion	Hs	cellular component
mitochondrial matrix	Hs	cellular component
generation of precursor metabolites and energy	Hs	biological process
glycolytic process	Hs	biological process
tricarboxylic acid cycle	Hs	biological process
metabolic process	Hs	biological process
oxidoreductase activity	Hs	molecular function
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Hs	molecular function
thiamine pyrophosphate binding	Hs	molecular function
oxoglutarate dehydrogenase complex	Hs	cellular component
oxidation-reduction process	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
oxoglutarate dehydrogenase (succinyl-transferring) activity	Hs	molecular function	794	0.0
protein binding	Hs	molecular function	503	5.69e-165
nucleus	Hs	cellular component	489	3.53e-159
mitochondrion	Hs	cellular component	794	0.0
mitochondrial matrix	Hs	cellular component	794	0.0
oxidoreductase activity	Hs	molecular function	794	0.0
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Hs	molecular function	794	0.0
thiamine pyrophosphate binding	Hs	molecular function	794	0.0
heat shock protein binding	Hs	molecular function	489	3.53e-159
mitochondrial membrane	Hs	cellular component	489	3.53e-159
oxoglutarate dehydrogenase (NAD+) activity	Hs	molecular function	489	3.53e-159
oxoglutarate dehydrogenase complex	Hs	cellular component	794	0.0
metal ion binding	Hs	molecular function	503	5.69e-165
chaperone binding	Hs	molecular function	489	3.53e-159

GO Term	Analysis	Type	e-value
oxoglutarate dehydrogenase (succinyl-transferring) activity	PANTHER	molecular function	1.1E-293
tricarboxylic acid cycle	PANTHER	biological process	1.1E-293
metabolic process	Pfam	biological process	2.6E-48
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Pfam	molecular function	2.6E-48
thiamine pyrophosphate binding	PANTHER	molecular function	1.1E-293
oxidation-reduction process	PANTHER	biological process	1.1E-293