IPR Term	Analysis	Definition
CUB_dom	ProSiteProfiles	CUB domain
CUB_dom	Pfam	CUB domain
Sperma_CUB_dom_sf	SUPERFAMILY	Spermadhesin, CUB domain superfamily
CUB_dom	CDD	CUB domain
CUB_dom	SMART	CUB domain
Sperma_CUB_dom_sf	Gene3D	Spermadhesin, CUB domain superfamily

GO Term	Annotation Origin	Type
metalloendopeptidase activity	Blast	molecular function
serine-type endopeptidase activity	Blast	molecular function
calcium ion binding	Blast	molecular function
protein binding	Orthology	molecular function
extracellular region	Orthology	cellular component
extracellular space	Blast	cellular component
nucleoplasm	Blast	cellular component
cytoplasm	Blast	cellular component
lysosome	Blast	cellular component
lysosomal membrane	Blast	cellular component
endosome	Blast	cellular component
endoplasmic reticulum	Blast	cellular component
Golgi apparatus	Blast	cellular component
cytosol	Blast	cellular component
plasma membrane	Orthology	cellular component
brush border	Blast	cellular component
peptidase activity	Blast	molecular function
serine-type peptidase activity	Blast	molecular function
metallopeptidase activity	Blast	molecular function
zinc ion binding	Blast	molecular function
membrane	Orthology	cellular component
apical plasma membrane	Blast	cellular component
hydrolase activity	Blast	molecular function
brush border membrane	Blast	cellular component
vesicle	Blast	cellular component
identical protein binding	Blast	molecular function
protein homodimerization activity	Blast	molecular function
apical part of cell	Blast	cellular component
metal ion binding	Blast	molecular function
extracellular exosome	Blast	cellular component
integral component of membrane	Orthology	cellular component
cell junction	Orthology	cellular component
synapse	Orthology	cellular component
postsynaptic membrane	Orthology	cellular component
nervous system process	Orthology	biological process
organelle	Orthology	cellular component
postsynapse	Orthology	cellular component
neuron part	Orthology	cellular component
receptor binding	Orthology	molecular function
chemical synaptic transmission	Orthology	biological process
regulation of signaling	Orthology	biological process
protein localization	Orthology	biological process
organelle part	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
transmembrane transport	Orthology	biological process
sodium ion transport	Orthology	biological process
transmembrane signaling receptor activity	Orthology	molecular function
regulation of molecular function	Orthology	biological process
anion binding	Orthology	molecular function
regulation of signal transduction	Orthology	biological process
small molecule binding	Orthology	molecular function
molecular function regulator	Blast	molecular function
signaling receptor activity	Blast	molecular function
membrane part	Blast	cellular component
endomembrane system	Blast	cellular component
binding	Blast	molecular function
intracellular organelle part	Blast	cellular component
whole membrane	Blast	cellular component
bounding membrane of organelle	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
plasma membrane part	Blast	cellular component
cell surface	Blast	cellular component
tetrapyrrole binding	Blast	molecular function
cofactor binding	Blast	molecular function
vacuolar part	Blast	cellular component
intracellular organelle lumen	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
protein binding	Hs	molecular function
extracellular region	Hs	cellular component
plasma membrane	Hs	cellular component
membrane	Hs	cellular component
memory	Hs	biological process
visual learning	Hs	biological process
postsynaptic density	Hs	cellular component
integral component of membrane	Hs	cellular component
cell junction	Hs	cellular component
ionotropic glutamate receptor binding	Hs	molecular function
synapse	Hs	cellular component
postsynaptic membrane	Hs	cellular component
regulation of neuronal synaptic plasticity	Hs	biological process
regulation of long-term neuronal synaptic plasticity	Hs	biological process
excitatory synapse	Hs	cellular component
receptor localization to synapse	Hs	biological process
postsynaptic density membrane	Hs	cellular component
regulation of kainate selective glutamate receptor activity	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
metalloendopeptidase activity	Hs	molecular function	55.1	5.77e-08
serine-type endopeptidase activity	Hs	molecular function	58.2	6.29e-09
receptor activity	Hs	molecular function	62.0	5.96e-10
cytokine activity	Hs	molecular function	55.1	5.77e-08
transporter activity	Hs	molecular function	62.0	5.96e-10
calcium ion binding	Hs	molecular function	62.0	5.96e-10
protein binding	Hs	molecular function	62.0	5.96e-10
extracellular region	Hs	cellular component	58.2	6.29e-09
proteinaceous extracellular matrix	Hs	cellular component	55.1	5.77e-08
extracellular space	Hs	cellular component	58.2	6.29e-09
nucleoplasm	Hs	cellular component	58.2	6.29e-09
cytoplasm	Hs	cellular component	62.0	5.96e-10
lysosome	Hs	cellular component	62.0	5.96e-10
lysosomal membrane	Hs	cellular component	62.0	5.96e-10
endosome	Hs	cellular component	62.0	5.96e-10
endoplasmic reticulum	Hs	cellular component	62.0	5.96e-10
Golgi apparatus	Hs	cellular component	62.0	5.96e-10
cytosol	Hs	cellular component	62.0	5.96e-10
plasma membrane	Hs	cellular component	62.0	5.96e-10
brush border	Hs	cellular component	62.0	5.96e-10
clathrin-coated pit	Hs	cellular component	62.0	5.96e-10
growth factor activity	Hs	molecular function	55.1	5.77e-08
drug binding	Hs	molecular function	62.0	5.96e-10
peptidase activity	Hs	molecular function	58.2	6.29e-09
serine-type peptidase activity	Hs	molecular function	58.2	6.29e-09
metallopeptidase activity	Hs	molecular function	55.1	5.77e-08
zinc ion binding	Hs	molecular function	55.1	5.77e-08
endosome membrane	Hs	cellular component	62.0	5.96e-10
membrane	Hs	cellular component	62.0	5.96e-10
apical plasma membrane	Hs	cellular component	62.0	5.96e-10
hydrolase activity	Hs	molecular function	58.2	6.29e-09
endocytic vesicle	Hs	cellular component	62.0	5.96e-10
extrinsic component of external side of plasma membrane	Hs	cellular component	62.0	5.96e-10
cobalamin binding	Hs	molecular function	62.0	5.96e-10
brush border membrane	Hs	cellular component	62.0	5.96e-10
vesicle	Hs	cellular component	55.1	5.77e-08
identical protein binding	Hs	molecular function	55.1	5.77e-08
protein homodimerization activity	Hs	molecular function	62.0	5.96e-10
lysosomal lumen	Hs	cellular component	62.0	5.96e-10
apical part of cell	Hs	cellular component	62.0	5.96e-10
metal ion binding	Hs	molecular function	62.0	5.96e-10
calcium-dependent protein binding	Hs	molecular function	58.2	6.29e-09
extracellular exosome	Hs	cellular component	62.0	5.96e-10