IPR Term	Analysis	Definition
ATPase_AAA_core	Pfam	ATPase, AAA-type, core
AAA+_ATPase	SMART	AAA+ ATPase domain
P-loop_NTPase	SUPERFAMILY	P-loop containing nucleoside triphosphate hydrolase

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
protein polyubiquitination	Orthology	biological process
receptor binding	Blast	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
extracellular region	Blast	cellular component
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
transcription factor binding	Orthology	molecular function
membrane	Orthology	cellular component
hydrolase activity	Orthology	molecular function
cytoplasmic vesicle	Blast	cellular component
identical protein binding	Orthology	molecular function
transmembrane transport	Orthology	biological process
extracellular exosome	Orthology	cellular component
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
postsynapse	Blast	cellular component
intracellular signal transduction	Orthology	biological process
protein phosphorylation	Orthology	biological process
intracellular part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
proteolysis	Orthology	biological process
G2/M transition of mitotic cell cycle	Orthology	biological process
peptidase activity, acting on L-amino acid peptides	Orthology	molecular function
nucleoside-triphosphatase activity	Orthology	molecular function
protein metabolic process	Orthology	biological process
cellular response to stress	Orthology	biological process
response to organic substance	Orthology	biological process
nuclear lumen	Orthology	cellular component
cytokine-mediated signaling pathway	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
cell surface receptor signaling pathway	Orthology	biological process
immune response	Orthology	biological process
mRNA catabolic process	Orthology	biological process
cellular protein modification process	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription initiation from RNA polymerase II promoter	Orthology	biological process
cell-cell signaling	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
animal organ development	Orthology	biological process
immune system process	Orthology	biological process
cell differentiation	Orthology	biological process
cytoplasmic part	Blast	cellular component
intracellular non-membrane-bounded organelle	Blast	cellular component
intracellular organelle part	Blast	cellular component
endomembrane system	Blast	cellular component
intracellular organelle lumen	Blast	cellular component
extracellular space	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
MAPK cascade	Hs	biological process
nucleotide binding	Hs	molecular function
protein polyubiquitination	Hs	biological process
proteasome complex	Hs	cellular component
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
ubiquitin-dependent protein catabolic process	Hs	biological process
proteasome regulatory particle, base subcomplex	Hs	cellular component
negative regulation of G2/M transition of mitotic cell cycle	Hs	biological process
membrane	Hs	cellular component
inclusion body	Hs	cellular component
protein deubiquitination	Hs	biological process
hydrolase activity	Hs	molecular function
ATPase activity	Hs	molecular function
TBP-class protein binding	Hs	molecular function
proteasome accessory complex	Hs	cellular component
protein catabolic process	Hs	biological process
ubiquitin-dependent ERAD pathway	Hs	biological process
protein binding, bridging	Hs	molecular function
anaphase-promoting complex-dependent catabolic process	Hs	biological process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Hs	biological process
nuclear proteasome complex	Hs	cellular component
cytosolic proteasome complex	Hs	cellular component
tumor necrosis factor-mediated signaling pathway	Hs	biological process
proteasome-activating ATPase activity	Hs	molecular function
NIK/NF-kappaB signaling	Hs	biological process
Fc-epsilon receptor signaling pathway	Hs	biological process
identical protein binding	Hs	molecular function
proteasome-mediated ubiquitin-dependent protein catabolic process	Hs	biological process
regulation of mRNA stability	Hs	biological process
post-translational protein modification	Hs	biological process
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	Hs	biological process
T cell receptor signaling pathway	Hs	biological process
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Hs	biological process
transmembrane transport	Hs	biological process
Wnt signaling pathway, planar cell polarity pathway	Hs	biological process
extracellular exosome	Hs	cellular component
interleukin-1-mediated signaling pathway	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process
positive regulation of proteasomal protein catabolic process	Hs	biological process
regulation of hematopoietic stem cell differentiation	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	293	1.78e-100
proteasome complex	Hs	cellular component	293	1.78e-100
P-body	Hs	cellular component	196	4.94e-62
receptor binding	Hs	molecular function	183	3.00e-57
protein binding	Hs	molecular function	293	1.78e-100
ATP binding	Hs	molecular function	293	1.78e-100
extracellular region	Hs	cellular component	196	4.94e-62
nucleus	Hs	cellular component	293	1.78e-100
nucleoplasm	Hs	cellular component	293	1.78e-100
cytoplasm	Hs	cellular component	293	1.78e-100
cytosol	Hs	cellular component	293	1.78e-100
proteasome regulatory particle	Hs	cellular component	183	3.00e-57
transcription factor binding	Hs	molecular function	183	3.00e-57
proteasome regulatory particle, base subcomplex	Hs	cellular component	293	1.78e-100
membrane	Hs	cellular component	293	1.78e-100
inclusion body	Hs	cellular component	293	1.78e-100
hydrolase activity	Hs	molecular function	293	1.78e-100
ATPase activity	Hs	molecular function	293	1.78e-100
TBP-class protein binding	Hs	molecular function	293	1.78e-100
proteasome accessory complex	Hs	cellular component	293	1.78e-100
protein binding, bridging	Hs	molecular function	293	1.78e-100
cytoplasmic vesicle	Hs	cellular component	183	3.00e-57
thyrotropin-releasing hormone receptor binding	Hs	molecular function	183	3.00e-57
nuclear proteasome complex	Hs	cellular component	293	1.78e-100
cytosolic proteasome complex	Hs	cellular component	293	1.78e-100
secretory granule lumen	Hs	cellular component	196	4.94e-62
proteasome-activating ATPase activity	Hs	molecular function	293	1.78e-100
cytoplasmic ribonucleoprotein granule	Hs	cellular component	196	4.94e-62
identical protein binding	Hs	molecular function	293	1.78e-100
extracellular exosome	Hs	cellular component	293	1.78e-100
blood microparticle	Hs	cellular component	183	3.00e-57
postsynapse	Hs	cellular component	183	3.00e-57
ficolin-1-rich granule lumen	Hs	cellular component	196	4.94e-62

GO Term	Analysis	Type	e-value
ATP binding	Pfam	molecular function	6.7E-31