Gene Card
Best human hits
ADGRE1; EGF; HMCN1
Species
Unique Gene ID
Phmamm.g00019081
Gene Model ID
Phmamm.CG.MTP2014.S6693.g19081
Location
S6693:82..2827
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
14 results
| IPR Term | Analysis | Definition |
|---|---|---|
| EGF-type_Asp/Asn_hydroxyl_site | ProSitePatterns | EGF-type aspartate/asparagine hydroxylation site |
| FN3_dom | ProSiteProfiles | Fibronectin type III |
| EGF-like_CS | ProSitePatterns | EGF-like, conserved site |
| FN3_dom | SMART | Fibronectin type III |
| FN3_dom | CDD | Fibronectin type III |
| EGF_Ca-bd_CS | ProSitePatterns | EGF-like calcium-binding, conserved site |
| FBN | PANTHER | Fibrillin |
| FN3_sf | SUPERFAMILY | Fibronectin type III superfamily |
| EGF-like_dom | ProSiteProfiles | EGF-like domain |
| Growth_fac_rcpt_cys_sf | SUPERFAMILY | Growth factor receptor cysteine-rich domain superfamily |
| Ig-like_fold | Gene3D | Immunoglobulin-like fold |
| EGF-like_Ca-bd_dom | SMART | EGF-like calcium-binding domain |
| EGF-like_Ca-bd_dom | Pfam | EGF-like calcium-binding domain |
| EGF-like_dom | SMART | EGF-like domain |
GOSlim
42 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| signal transducer activity | Blast | molecular function |
| transmembrane signaling receptor activity | Blast | molecular function |
| G-protein coupled receptor activity | Blast | molecular function |
| calcium ion binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| extracellular space | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| lysosomal membrane | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| integral component of plasma membrane | Blast | cellular component |
| cell surface receptor signaling pathway | Blast | biological process |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| cell junction | Blast | cellular component |
| extracellular exosome | Blast | cellular component |
| cell periphery | Blast | cellular component |
| protein kinase activity | Blast | molecular function |
| enzyme binding | Blast | molecular function |
| molecular function regulator | Blast | molecular function |
| receptor binding | Blast | molecular function |
| extracellular region part | Blast | cellular component |
| cytoplasmic part | Blast | cellular component |
| regulation of signal transduction | Blast | biological process |
| signaling receptor activity | Blast | molecular function |
| plasma membrane part | Blast | cellular component |
| cell surface | Blast | cellular component |
| enzyme activator activity | Blast | molecular function |
| protein kinase binding | Blast | molecular function |
| intracellular organelle part | Blast | cellular component |
| whole membrane | Blast | cellular component |
| cytoplasmic vesicle | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| endomembrane system | Blast | cellular component |
| intracellular organelle lumen | Blast | cellular component |
| plasma membrane region | Blast | cellular component |
| cell-cell signaling | Blast | biological process |
| macromolecular complex | Blast | cellular component |
| phosphotransferase activity, alcohol group as acceptor | Blast | molecular function |
| organic substance metabolic process | Blast | biological process |
| kinase activity | Blast | molecular function |
| structural molecule activity | InterProScan | molecular function |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
33 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| protein tyrosine kinase activity | Hs | molecular function | 73.9 | 3.48e-14 |
| signal transducer activity | Hs | molecular function | 69.7 | 7.61e-13 |
| transmembrane signaling receptor activity | Hs | molecular function | 69.7 | 7.61e-13 |
| G-protein coupled receptor activity | Hs | molecular function | 69.7 | 7.61e-13 |
| Ras guanyl-nucleotide exchange factor activity | Hs | molecular function | 73.9 | 3.48e-14 |
| epidermal growth factor receptor binding | Hs | molecular function | 73.9 | 3.48e-14 |
| calcium ion binding | Hs | molecular function | 73.9 | 3.48e-14 |
| protein binding | Hs | molecular function | 73.9 | 3.48e-14 |
| extracellular region | Hs | cellular component | 73.9 | 3.48e-14 |
| proteinaceous extracellular matrix | Hs | cellular component | 70.9 | 3.91e-13 |
| basement membrane | Hs | cellular component | 70.9 | 3.91e-13 |
| extracellular space | Hs | cellular component | 73.9 | 3.48e-14 |
| cytoplasm | Hs | cellular component | 70.9 | 3.91e-13 |
| lysosomal membrane | Hs | cellular component | 73.9 | 3.48e-14 |
| plasma membrane | Hs | cellular component | 73.9 | 3.48e-14 |
| integral component of plasma membrane | Hs | cellular component | 69.7 | 7.61e-13 |
| cell cortex | Hs | cellular component | 70.9 | 3.91e-13 |
| growth factor activity | Hs | molecular function | 73.9 | 3.48e-14 |
| external side of plasma membrane | Hs | cellular component | 69.7 | 7.61e-13 |
| membrane | Hs | cellular component | 73.9 | 3.48e-14 |
| integral component of membrane | Hs | cellular component | 73.9 | 3.48e-14 |
| Wnt-protein binding | Hs | molecular function | 73.9 | 3.48e-14 |
| cell junction | Hs | cellular component | 70.9 | 3.91e-13 |
| transmembrane receptor protein tyrosine kinase activator activity | Hs | molecular function | 73.9 | 3.48e-14 |
| clathrin-coated vesicle membrane | Hs | cellular component | 73.9 | 3.48e-14 |
| extracellular matrix | Hs | cellular component | 70.9 | 3.91e-13 |
| platelet alpha granule lumen | Hs | cellular component | 73.9 | 3.48e-14 |
| cleavage furrow | Hs | cellular component | 70.9 | 3.91e-13 |
| Wnt-activated receptor activity | Hs | molecular function | 73.9 | 3.48e-14 |
| receptor complex | Hs | cellular component | 73.9 | 3.48e-14 |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | Hs | molecular function | 73.9 | 3.48e-14 |
| extracellular exosome | Hs | cellular component | 73.9 | 3.48e-14 |
| cell periphery | Hs | cellular component | 69.7 | 7.61e-13 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| calcium ion binding | PANTHER | molecular function | 4.9E-26 |
| protein binding | SUPERFAMILY | molecular function | 2.65E-19 |
| proteinaceous extracellular matrix | PANTHER | cellular component | 4.9E-26 |
| extracellular matrix structural constituent | PANTHER | molecular function | 4.9E-26 |
