Gene Card
Best human hits
NAE1; SAE1; UBA7
Species
Unique Gene ID
Boschl.g00043574
Gene Model ID
Boschl.CG.Botznik2013.chr12.g43574
Location
chr12:9588427..9590017
Transcript Models and Sequences
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
4 results
| IPR Term | Analysis | Definition |
|---|---|---|
| ThiF_NAD_FAD-bd | Pfam | THIF-type NAD/FAD binding fold |
| APP-BP1 | PANTHER | NEDD8-activating enzyme E1 regulatory subunit APP-BP1 |
| APP-BP1 | PIRSF | NEDD8-activating enzyme E1 regulatory subunit APP-BP1 |
| Ubiquitin-activating_enz | SUPERFAMILY | Ubiquitin-activating enzyme |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
18 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| protein binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| cytosol | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| apoptotic process | Hs | biological process |
| cell cycle | Hs | biological process |
| signal transduction | Hs | biological process |
| ubiquitin-like modifier activating enzyme activity | Hs | molecular function |
| membrane | Hs | cellular component |
| NEDD8 activating enzyme activity | Hs | molecular function |
| ubiquitin protein ligase binding | Hs | molecular function |
| mitotic DNA replication checkpoint | Hs | biological process |
| regulation of apoptotic process | Hs | biological process |
| regulation of neuron apoptotic process | Hs | biological process |
| post-translational protein modification | Hs | biological process |
| protein neddylation | Hs | biological process |
| protein heterodimerization activity | Hs | molecular function |
| neuron apoptotic process | Hs | biological process |
GO (Blast)
23 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 61.6 | 6.75e-10 |
| ubiquitin activating enzyme activity | Hs | molecular function | 90.5 | 8.99e-20 |
| ubiquitin-protein transferase activity | Hs | molecular function | 61.6 | 6.75e-10 |
| protein binding | Hs | molecular function | 524 | 0.0 |
| ATP binding | Hs | molecular function | 61.6 | 6.75e-10 |
| nucleus | Hs | cellular component | 90.5 | 8.99e-20 |
| nucleoplasm | Hs | cellular component | 90.5 | 8.99e-20 |
| cytoplasm | Hs | cellular component | 524 | 0.0 |
| cytosol | Hs | cellular component | 524 | 0.0 |
| plasma membrane | Hs | cellular component | 524 | 0.0 |
| protein C-terminus binding | Hs | molecular function | 90.5 | 8.99e-20 |
| enzyme activator activity | Hs | molecular function | 90.5 | 8.99e-20 |
| ubiquitin-like modifier activating enzyme activity | Hs | molecular function | 524 | 0.0 |
| membrane | Hs | cellular component | 524 | 0.0 |
| ligase activity | Hs | molecular function | 90.5 | 8.99e-20 |
| NEDD8 activating enzyme activity | Hs | molecular function | 524 | 0.0 |
| ISG15 activating enzyme activity | Hs | molecular function | 61.6 | 6.75e-10 |
| SUMO activating enzyme activity | Hs | molecular function | 90.5 | 8.99e-20 |
| SUMO activating enzyme complex | Hs | cellular component | 90.5 | 8.99e-20 |
| ubiquitin protein ligase binding | Hs | molecular function | 524 | 0.0 |
| ATP-dependent protein binding | Hs | molecular function | 90.5 | 8.99e-20 |
| small protein activating enzyme binding | Hs | molecular function | 90.5 | 8.99e-20 |
| protein heterodimerization activity | Hs | molecular function | 524 | 0.0 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| ubiquitin-like modifier activating enzyme activity | SUPERFAMILY | molecular function | 1.15E-116 |
| NEDD8 activating enzyme activity | PIRSF | molecular function | 3.4E-161 |
| protein neddylation | PIRSF | biological process | 3.4E-161 |
