Gene Card
Best human hits
FBXW11; FBXW7; TRAF7
Species
Unique Gene ID
Cisavi.g00002162
Gene Model ID
Cisavi.CG.ENS81.R14.269107-274473
Location
R14:269106..274473
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
14 results
| IPR Term | Analysis | Definition |
|---|---|---|
| TRAF-like | SUPERFAMILY | TRAF-like |
| WD40_repeat_CS | ProSitePatterns | WD40 repeat, conserved site |
| Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
| WD40_repeat | ProSiteProfiles | WD40 repeat |
| Znf_RING | SMART | Zinc finger, RING-type |
| WD40/YVTN_repeat-like_dom_sf | Gene3D | WD40/YVTN repeat-like-containing domain superfamily |
| Znf_RING | ProSiteProfiles | Zinc finger, RING-type |
| WD40_repeat | SMART | WD40 repeat |
| Znf_TRAF | ProSiteProfiles | Zinc finger, TRAF-type |
| WD40_repeat | Pfam | WD40 repeat |
| WD40_repeat_dom_sf | SUPERFAMILY | WD40-repeat-containing domain superfamily |
| Znf-RING_LisH | Pfam | RING-type zinc-finger, LisH dimerisation motif |
| WD40_repeat_dom | ProSiteProfiles | WD40-repeat-containing domain |
| G-protein_beta_WD-40_rep | PRINTS | G-protein beta WD-40 repeat |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
16 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| ubiquitin ligase complex | Hs | cellular component |
| activation of MAPKKK activity | Hs | biological process |
| ubiquitin-protein transferase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| plasma membrane | Hs | cellular component |
| transcription, DNA-templated | Hs | biological process |
| regulation of transcription, DNA-templated | Hs | biological process |
| apoptotic process | Hs | biological process |
| zinc ion binding | Hs | molecular function |
| protein ubiquitination | Hs | biological process |
| transferase activity | Hs | molecular function |
| cytoplasmic vesicle | Hs | cellular component |
| intracellular membrane-bounded organelle | Hs | cellular component |
| positive regulation of MAPK cascade | Hs | biological process |
| metal ion binding | Hs | molecular function |
| positive regulation of apoptotic signaling pathway | Hs | biological process |
GO (Blast)
25 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| ubiquitin ligase complex | Hs | cellular component | 771 | 0.0 |
| ubiquitin-protein transferase activity | Hs | molecular function | 771 | 0.0 |
| protein binding | Hs | molecular function | 771 | 0.0 |
| nucleus | Hs | cellular component | 119 | 2.44e-28 |
| nucleoplasm | Hs | cellular component | 119 | 2.44e-28 |
| nucleolus | Hs | cellular component | 119 | 2.44e-28 |
| cytoplasm | Hs | cellular component | 119 | 2.44e-28 |
| centrosome | Hs | cellular component | 115 | 2.52e-27 |
| cytosol | Hs | cellular component | 119 | 2.44e-28 |
| plasma membrane | Hs | cellular component | 771 | 0.0 |
| zinc ion binding | Hs | molecular function | 771 | 0.0 |
| transferase activity | Hs | molecular function | 771 | 0.0 |
| SCF ubiquitin ligase complex | Hs | cellular component | 119 | 2.44e-28 |
| cyclin binding | Hs | molecular function | 119 | 2.44e-28 |
| protein binding, bridging | Hs | molecular function | 119 | 2.44e-28 |
| cytoplasmic vesicle | Hs | cellular component | 771 | 0.0 |
| ubiquitin protein ligase binding | Hs | molecular function | 119 | 2.44e-28 |
| identical protein binding | Hs | molecular function | 119 | 2.44e-28 |
| intracellular membrane-bounded organelle | Hs | cellular component | 771 | 0.0 |
| metal ion binding | Hs | molecular function | 771 | 0.0 |
| protein dimerization activity | Hs | molecular function | 115 | 2.52e-27 |
| phosphothreonine residue binding | Hs | molecular function | 119 | 2.44e-28 |
| ubiquitin protein ligase activity | Hs | molecular function | 115 | 2.52e-27 |
| ubiquitin-protein transferase activator activity | Hs | molecular function | 119 | 2.44e-28 |
| Parkin-FBXW7-Cul1 ubiquitin ligase complex | Hs | cellular component | 119 | 2.44e-28 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | SUPERFAMILY | molecular function | 2.44E-66 |
| zinc ion binding | ProSiteProfiles | molecular function | 9.592 |
