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Gene Card

Best human hits

CDK12; CDK13; CDK9

Species

C.savignyi

Unique Gene ID

Cisavi.g00005996

Gene Model ID

Cisavi.CG.ENS81.R3.1636911-1641553

Location

R3:1636910..1641553

Transcript Models and Sequences

  Cisavi.CG.ENS81.R3.1636911-1641553.11356.t
Cisavi.CG.ENS81.R3.1636911-1641553.11357.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom SMART Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
transcription coactivator binding Hs molecular function
DNA binding Hs molecular function
chromatin binding Hs molecular function
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
cyclin-dependent protein serine/threonine kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
chromosome Hs cellular component
cytoplasm Hs cellular component
DNA repair Hs biological process
regulation of DNA repair Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription from RNA polymerase II promoter Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
transcription elongation from RNA polymerase II promoter Hs biological process
protein phosphorylation Hs biological process
cellular response to DNA damage stimulus Hs biological process
transcription elongation factor complex Hs cellular component
cyclin/CDK positive transcription elongation factor complex Hs cellular component
transcription factor binding Hs molecular function
cell proliferation Hs biological process
RNA polymerase II carboxy-terminal domain kinase activity Hs molecular function
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
PML body Hs cellular component
transferase activity Hs molecular function
snRNA binding Hs molecular function
protein kinase binding Hs molecular function
cyclin binding Hs molecular function
replication fork processing Hs biological process
positive regulation of histone phosphorylation Hs biological process
cytoplasmic ribonucleoprotein granule Hs cellular component
response to drug Hs biological process
snRNA transcription from RNA polymerase II promoter Hs biological process
transcription regulatory region DNA binding Hs molecular function
positive regulation of transcription from RNA polymerase II promoter Hs biological process
phosphorylation of RNA polymerase II C-terminal domain Hs biological process
negative regulation of cell cycle arrest Hs biological process
7SK snRNA binding Hs molecular function
negative regulation of mRNA polyadenylation Hs biological process
positive regulation of histone H2B ubiquitination Hs biological process

GO (Blast)

39 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 572 0.0
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 572 0.0
transcription coactivator binding Hs molecular function 572 0.0
fibrillar center Hs cellular component 278 5.53e-84
cyclin K-CDK12 complex Hs cellular component 278 5.53e-84
cyclin K-CDK13 complex Hs cellular component 282 2.35e-85
DNA binding Hs molecular function 572 0.0
chromatin binding Hs molecular function 572 0.0
RNA binding Hs molecular function 282 2.35e-85
protein kinase activity Hs molecular function 572 0.0
protein serine/threonine kinase activity Hs molecular function 572 0.0
cyclin-dependent protein serine/threonine kinase activity Hs molecular function 572 0.0
protein binding Hs molecular function 572 0.0
ATP binding Hs molecular function 572 0.0
extracellular region Hs cellular component 282 2.35e-85
extracellular space Hs cellular component 282 2.35e-85
nucleus Hs cellular component 572 0.0
nucleoplasm Hs cellular component 572 0.0
chromosome Hs cellular component 572 0.0
cytoplasm Hs cellular component 572 0.0
Golgi apparatus Hs cellular component 282 2.35e-85
cytosol Hs cellular component 282 2.35e-85
transcription elongation factor complex Hs cellular component 572 0.0
cyclin/CDK positive transcription elongation factor complex Hs cellular component 572 0.0
transcription factor binding Hs molecular function 572 0.0
RNA polymerase II carboxy-terminal domain kinase activity Hs molecular function 572 0.0
membrane Hs cellular component 572 0.0
kinase activity Hs molecular function 572 0.0
PML body Hs cellular component 572 0.0
nuclear speck Hs cellular component 282 2.35e-85
transferase activity Hs molecular function 572 0.0
snRNA binding Hs molecular function 572 0.0
protein kinase binding Hs molecular function 572 0.0
nuclear cyclin-dependent protein kinase holoenzyme complex Hs cellular component 282 2.35e-85
cyclin binding Hs molecular function 572 0.0
cytoplasmic ribonucleoprotein granule Hs cellular component 572 0.0
transcription regulatory region DNA binding Hs molecular function 572 0.0
7SK snRNA binding Hs molecular function 572 0.0
ficolin-1-rich granule lumen Hs cellular component 282 2.35e-85

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity SMART molecular function 7.6E-89
ATP binding SMART molecular function 7.6E-89
protein phosphorylation SMART biological process 7.6E-89

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