Gene Card
Best human hits
NAE1; SAE1
Species
Unique Gene ID
Moocul.g00006562
Gene Model ID
Moocul.CG.ELv1_2.S85796.g06562
Location
S85796:130..6416
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
APP-BP1 | PANTHER | NEDD8-activating enzyme E1 regulatory subunit APP-BP1 |
Ubiquitin-activating_enz | SUPERFAMILY | Ubiquitin-activating enzyme |
ThiF_NAD_FAD-bd | Pfam | THIF-type NAD/FAD binding fold |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
apoptotic process | Hs | biological process |
cell cycle | Hs | biological process |
signal transduction | Hs | biological process |
ubiquitin-like modifier activating enzyme activity | Hs | molecular function |
membrane | Hs | cellular component |
NEDD8 activating enzyme activity | Hs | molecular function |
ubiquitin protein ligase binding | Hs | molecular function |
mitotic DNA replication checkpoint | Hs | biological process |
regulation of apoptotic process | Hs | biological process |
regulation of neuron apoptotic process | Hs | biological process |
post-translational protein modification | Hs | biological process |
protein neddylation | Hs | biological process |
protein heterodimerization activity | Hs | molecular function |
neuron apoptotic process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin activating enzyme activity | Hs | molecular function | 46.2 | 2.40e-05 |
protein binding | Hs | molecular function | 372 | 2.13e-124 |
nucleus | Hs | cellular component | 46.2 | 2.40e-05 |
nucleoplasm | Hs | cellular component | 46.2 | 2.40e-05 |
cytoplasm | Hs | cellular component | 372 | 2.13e-124 |
cytosol | Hs | cellular component | 372 | 2.13e-124 |
plasma membrane | Hs | cellular component | 372 | 2.13e-124 |
protein C-terminus binding | Hs | molecular function | 46.2 | 2.40e-05 |
enzyme activator activity | Hs | molecular function | 46.2 | 2.40e-05 |
ubiquitin-like modifier activating enzyme activity | Hs | molecular function | 372 | 2.13e-124 |
membrane | Hs | cellular component | 372 | 2.13e-124 |
ligase activity | Hs | molecular function | 46.2 | 2.40e-05 |
NEDD8 activating enzyme activity | Hs | molecular function | 372 | 2.13e-124 |
SUMO activating enzyme activity | Hs | molecular function | 46.2 | 2.40e-05 |
SUMO activating enzyme complex | Hs | cellular component | 46.2 | 2.40e-05 |
ubiquitin protein ligase binding | Hs | molecular function | 372 | 2.13e-124 |
ATP-dependent protein binding | Hs | molecular function | 46.2 | 2.40e-05 |
small protein activating enzyme binding | Hs | molecular function | 46.2 | 2.40e-05 |
protein heterodimerization activity | Hs | molecular function | 372 | 2.13e-124 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-like modifier activating enzyme activity | SUPERFAMILY | molecular function | 7.98E-74 |
NEDD8 activating enzyme activity | PANTHER | molecular function | 2.5E-79 |
protein neddylation | PANTHER | biological process | 2.5E-79 |