Gene Card
Best human hits
HERC1; HERC2
Unique Gene ID
Cirobu.g00016005
Gene Model ID
NCBI:KH.108950945
Location
KhS778:522..24584
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Mib_Herc2_sf | Gene3D | Mib/herc2 domain superfamily |
RCC1/BLIP-II | Gene3D | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
Rib_L2_dom2 | Gene3D | Ribosomal protein L2, domain 2 |
Reg_chr_condens | PRINTS | Regulator of chromosome condensation, RCC1 |
Mib_Herc2_sf | SUPERFAMILY | Mib/herc2 domain superfamily |
RCC1/BLIP-II | SUPERFAMILY | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
CPH_domain | Pfam | CPH domain |
Mib_Herc2 | ProSiteProfiles | Mib-herc2 |
Reg_chr_condens | Pfam | Regulator of chromosome condensation, RCC1 |
Reg_chr_condens | ProSiteProfiles | Regulator of chromosome condensation, RCC1 |
Mib_Herc2 | Pfam | Mib-herc2 |
GO Term | Annotation Origin | Type |
---|---|---|
ubiquitin-protein transferase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrial inner membrane | Orthology | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Blast | cellular component |
cytoskeleton | Orthology | cellular component |
DNA repair | Orthology | biological process |
intracellular protein transport | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
spermatogenesis | Orthology | biological process |
zinc ion binding | Orthology | molecular function |
membrane | Orthology | cellular component |
protein ubiquitination | Orthology | biological process |
transferase activity | Orthology | molecular function |
ubiquitin protein ligase binding | Orthology | molecular function |
metal ion binding | Orthology | molecular function |
regulation of molecular function | Orthology | biological process |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
cytoplasmic part | Orthology | cellular component |
microtubule organizing center | Orthology | cellular component |
proteolysis | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ubiquitin-protein transferase activity | Hs | molecular function |
guanyl-nucleotide exchange factor activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrial inner membrane | Hs | cellular component |
centriole | Hs | cellular component |
cytoskeleton | Hs | cellular component |
DNA repair | Hs | biological process |
double-strand break repair via nonhomologous end joining | Hs | biological process |
intracellular protein transport | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
spermatogenesis | Hs | biological process |
zinc ion binding | Hs | molecular function |
membrane | Hs | cellular component |
protein ubiquitination | Hs | biological process |
transferase activity | Hs | molecular function |
ubiquitin protein ligase binding | Hs | molecular function |
SUMO binding | Hs | molecular function |
proteasome-mediated ubiquitin-dependent protein catabolic process | Hs | biological process |
metal ion binding | Hs | molecular function |
ubiquitin protein ligase activity | Hs | molecular function |
regulation of molecular function | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin-protein transferase activity | Hs | molecular function | 745 | 0.0 |
guanyl-nucleotide exchange factor activity | Hs | molecular function | 745 | 0.0 |
ARF guanyl-nucleotide exchange factor activity | Hs | molecular function | 172 | 2.65e-42 |
protein binding | Hs | molecular function | 745 | 0.0 |
nucleus | Hs | cellular component | 745 | 0.0 |
nucleoplasm | Hs | cellular component | 745 | 0.0 |
cytoplasm | Hs | cellular component | 745 | 0.0 |
mitochondrial inner membrane | Hs | cellular component | 745 | 0.0 |
Golgi apparatus | Hs | cellular component | 172 | 2.65e-42 |
centriole | Hs | cellular component | 745 | 0.0 |
cytosol | Hs | cellular component | 172 | 2.65e-42 |
cytoskeleton | Hs | cellular component | 745 | 0.0 |
zinc ion binding | Hs | molecular function | 745 | 0.0 |
membrane | Hs | cellular component | 745 | 0.0 |
transferase activity | Hs | molecular function | 745 | 0.0 |
ubiquitin protein ligase binding | Hs | molecular function | 745 | 0.0 |
SUMO binding | Hs | molecular function | 745 | 0.0 |
metal ion binding | Hs | molecular function | 745 | 0.0 |
ubiquitin protein ligase activity | Hs | molecular function | 745 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-protein transferase activity | Gene3D | molecular function | 9.7E-24 |
protein ubiquitination | Pfam | biological process | 2.0E-18 |
metal ion binding | Gene3D | molecular function | 9.7E-24 |