IPR Term	Analysis	Definition
Tropomyosin	PRINTS	Tropomyosin
Tropomyosin	Pfam	Tropomyosin

GO Term	Annotation Origin	Type
actin binding	Orthology	molecular function
calcium ion binding	Orthology	molecular function
protein binding	Orthology	molecular function
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Orthology	cellular component
focal adhesion	Orthology	cellular component
membrane	Orthology	cellular component
identical protein binding	Orthology	molecular function
protein homodimerization activity	Orthology	molecular function
metal ion binding	Orthology	molecular function
protein heterodimerization activity	Orthology	molecular function
actin filament binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
cytoskeletal protein binding	Orthology	molecular function
integral component of membrane	Orthology	cellular component
wound healing	Orthology	biological process
cell differentiation	Orthology	biological process
cytoskeletal part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
organelle organization	Orthology	biological process
structural molecule activity	Orthology	molecular function
cell periphery	Orthology	cellular component
nucleoside-triphosphatase activity	Orthology	molecular function
cell morphogenesis	Orthology	biological process
intracellular non-membrane-bounded organelle	Orthology	cellular component
organelle part	Orthology	cellular component
cell migration	Orthology	biological process
cell projection organization	Orthology	biological process
cell projection	Orthology	cellular component
plasma membrane region	Orthology	cellular component
cell projection membrane	Orthology	cellular component
cell leading edge	Orthology	cellular component
positive regulation of hydrolase activity	Orthology	biological process
cellular response to stress	Orthology	biological process
response to oxidative stress	Orthology	biological process
cell development	Orthology	biological process
cell adhesion	Orthology	biological process
heart development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
osteoblast differentiation	Hs	biological process
stress fiber	Hs	cellular component
podosome	Hs	cellular component
actin binding	Hs	molecular function
calcium ion binding	Hs	molecular function
protein binding	Hs	molecular function
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
cytoskeleton	Hs	cellular component
muscle thin filament tropomyosin	Hs	cellular component
actin filament	Hs	cellular component
focal adhesion	Hs	cellular component
muscle contraction	Hs	biological process
actin filament organization	Hs	biological process
structural constituent of muscle	Hs	molecular function
actin cytoskeleton	Hs	cellular component
membrane	Hs	cellular component
cortical cytoskeleton	Hs	cellular component
filamentous actin	Hs	cellular component
identical protein binding	Hs	molecular function
protein homodimerization activity	Hs	molecular function
regulation of ATPase activity	Hs	biological process
metal ion binding	Hs	molecular function
protein heterodimerization activity	Hs	molecular function
actin filament binding	Hs	molecular function
extracellular exosome	Hs	cellular component
structural constituent of cytoskeleton	Hs	molecular function
regulation of muscle contraction	Hs	biological process
cytoskeleton organization	Hs	biological process
regulation of heart contraction	Hs	biological process
cytoskeletal protein binding	Hs	molecular function
regulation of cell shape	Hs	biological process
integral component of membrane	Hs	cellular component
myofibril	Hs	cellular component
sarcomere	Hs	cellular component
negative regulation of cell migration	Hs	biological process
ruffle organization	Hs	biological process
bleb	Hs	cellular component
ruffle membrane	Hs	cellular component
positive regulation of ATPase activity	Hs	biological process
cellular response to reactive oxygen species	Hs	biological process
wound healing	Hs	biological process
sarcomere organization	Hs	biological process
positive regulation of cell adhesion	Hs	biological process
positive regulation of stress fiber assembly	Hs	biological process
ventricular cardiac muscle tissue morphogenesis	Hs	biological process
cardiac muscle contraction	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
stress fiber	Hs	cellular component	312	2.08e-107
podosome	Hs	cellular component	312	2.08e-107
actin binding	Hs	molecular function	312	2.08e-107
calcium ion binding	Hs	molecular function	312	2.08e-107
protein binding	Hs	molecular function	312	2.08e-107
cytoplasm	Hs	cellular component	312	2.08e-107
cytosol	Hs	cellular component	312	2.08e-107
cytoskeleton	Hs	cellular component	312	2.08e-107
muscle thin filament tropomyosin	Hs	cellular component	312	2.08e-107
actin filament	Hs	cellular component	312	2.08e-107
focal adhesion	Hs	cellular component	312	2.08e-107
structural constituent of muscle	Hs	molecular function	312	2.08e-107
actin cytoskeleton	Hs	cellular component	310	8.16e-106
membrane	Hs	cellular component	312	2.08e-107
cortical cytoskeleton	Hs	cellular component	312	2.08e-107
filamentous actin	Hs	cellular component	312	2.08e-107
identical protein binding	Hs	molecular function	312	2.08e-107
protein homodimerization activity	Hs	molecular function	312	2.08e-107
metal ion binding	Hs	molecular function	312	2.08e-107
protein heterodimerization activity	Hs	molecular function	312	2.08e-107
actin filament binding	Hs	molecular function	312	2.08e-107
extracellular exosome	Hs	cellular component	312	2.08e-107