IPR Term	Analysis	Definition
Actinin_actin-bd_CS	ProSitePatterns	Actinin-type actin-binding domain, conserved site
DIX	Pfam	DIX domain
Dsh/Dvl-rel	PANTHER	Dishevelled-related protein
CH-domain	SMART	Calponin homology domain
CH_dom_sf	SUPERFAMILY	CH domain superfamily
CH-domain	ProSiteProfiles	Calponin homology domain
CH-domain	Pfam	Calponin homology domain
CH_dom_sf	Gene3D	CH domain superfamily
DIX	ProSiteProfiles	DIX domain
DIX_dom_sf	Gene3D	DIX domain superfamily
CH-domain	CDD	Calponin homology domain
DIX	SMART	DIX domain
Ubiquitin-like_domsf	SUPERFAMILY	Ubiquitin-like domain superfamily

GO Term	Annotation Origin	Type
RNA polymerase II regulatory region sequence-specific DNA binding	Blast	molecular function
nucleoside binding	Blast	molecular function
RNA binding	Blast	molecular function
actin binding	Orthology	molecular function
integrin binding	Blast	molecular function
calcium ion binding	Blast	molecular function
protein binding	Orthology	molecular function
extracellular region	Blast	cellular component
extracellular space	Blast	cellular component
intracellular	Blast	cellular component
nucleus	Blast	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Blast	cellular component
plasma membrane	Blast	cellular component
brush border	Blast	cellular component
focal adhesion	Orthology	cellular component
cell cycle	Orthology	biological process
multicellular organism development	Orthology	biological process
membrane	Blast	cellular component
nuclear body	Blast	cellular component
cell junction	Orthology	cellular component
positive regulation of Wnt signaling pathway	Orthology	biological process
macromolecular complex	Blast	cellular component
protein homodimerization activity	Blast	molecular function
cell projection	Blast	cellular component
metal ion binding	Blast	molecular function
perinuclear region of cytoplasm	Blast	cellular component
actin filament binding	Blast	molecular function
extracellular exosome	Blast	cellular component
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
cell proliferation	Orthology	biological process
brain development	Orthology	biological process
organelle organization	Orthology	biological process
tubulin binding	Orthology	molecular function
cell development	Orthology	biological process
neuron differentiation	Orthology	biological process
microtubule-based process	Orthology	biological process
cytoskeletal part	Blast	cellular component
plasma membrane region	Blast	cellular component
cell leading edge	Blast	cellular component
adherens junction	Blast	cellular component
cytoskeletal protein binding	Blast	molecular function
cytoplasmic part	Blast	cellular component
organelle part	Blast	cellular component
intracellular non-membrane-bounded organelle	Blast	cellular component
transcription coactivator activity	Blast	molecular function
intracellular organelle part	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
endomembrane system	Blast	cellular component
intracellular organelle lumen	Blast	cellular component
chromatin binding	Blast	molecular function
DNA binding	Blast	molecular function
receptor binding	Blast	molecular function
transcription factor binding	Blast	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
actin binding	Hs	molecular function
protein binding	Hs	molecular function
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
focal adhesion	Hs	cellular component
cell cycle	Hs	biological process
multicellular organism development	Hs	biological process
Wnt signaling pathway	Hs	biological process
protein domain specific binding	Hs	molecular function
cell proliferation in forebrain	Hs	biological process
cell junction	Hs	cellular component
positive regulation of Wnt signaling pathway	Hs	biological process
regulation of actin cytoskeleton organization	Hs	biological process
gamma-tubulin binding	Hs	molecular function
negative regulation of neuron differentiation	Hs	biological process
canonical Wnt signaling pathway	Hs	biological process
regulation of microtubule cytoskeleton organization	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function	77.4	5.76e-15
stress fiber	Hs	cellular component	78.6	2.55e-15
ruffle	Hs	cellular component	78.6	2.55e-15
nucleoside binding	Hs	molecular function	77.4	5.76e-15
RNA binding	Hs	molecular function	77.4	5.76e-15
double-stranded RNA binding	Hs	molecular function	78.6	2.55e-15
actin binding	Hs	molecular function	132	3.06e-33
integrin binding	Hs	molecular function	78.6	2.55e-15
calcium ion binding	Hs	molecular function	78.6	2.55e-15
protein binding	Hs	molecular function	132	3.06e-33
extracellular region	Hs	cellular component	78.6	2.55e-15
extracellular space	Hs	cellular component	78.6	2.55e-15
intracellular	Hs	cellular component	78.6	2.55e-15
nucleus	Hs	cellular component	77.4	5.76e-15
cytoplasm	Hs	cellular component	132	3.06e-33
cytosol	Hs	cellular component	132	3.06e-33
cytoskeleton	Hs	cellular component	78.6	2.55e-15
actin filament	Hs	cellular component	78.6	2.55e-15
plasma membrane	Hs	cellular component	78.6	2.55e-15
brush border	Hs	cellular component	78.6	2.55e-15
cell-cell junction	Hs	cellular component	78.6	2.55e-15
fascia adherens	Hs	cellular component	78.6	2.55e-15
focal adhesion	Hs	cellular component	132	3.06e-33
actin cytoskeleton	Hs	cellular component	77.4	5.76e-15
membrane	Hs	cellular component	78.6	2.55e-15
nuclear body	Hs	cellular component	77.4	5.76e-15
vinculin binding	Hs	molecular function	78.6	2.55e-15
protein domain specific binding	Hs	molecular function	132	3.06e-33
sarcomere	Hs	cellular component	78.6	2.55e-15
Z disc	Hs	cellular component	78.6	2.55e-15
cell junction	Hs	cellular component	132	3.06e-33
ligand-dependent nuclear receptor transcription coactivator activity	Hs	molecular function	78.6	2.55e-15
intracellular ribonucleoprotein complex	Hs	cellular component	77.4	5.76e-15
platelet alpha granule lumen	Hs	cellular component	78.6	2.55e-15
pseudopodium	Hs	cellular component	78.6	2.55e-15
chromatin DNA binding	Hs	molecular function	77.4	5.76e-15
macromolecular complex	Hs	cellular component	77.4	5.76e-15
nuclear hormone receptor binding	Hs	molecular function	77.4	5.76e-15
protein homodimerization activity	Hs	molecular function	78.6	2.55e-15
retinoic acid receptor binding	Hs	molecular function	77.4	5.76e-15
cell projection	Hs	cellular component	78.6	2.55e-15
gamma-tubulin binding	Hs	molecular function	132	3.06e-33
ion channel binding	Hs	molecular function	78.6	2.55e-15
metal ion binding	Hs	molecular function	78.6	2.55e-15
perinuclear region of cytoplasm	Hs	cellular component	77.4	5.76e-15
actin filament binding	Hs	molecular function	78.6	2.55e-15
extracellular exosome	Hs	cellular component	78.6	2.55e-15

GO Term	Analysis	Type	e-value
protein binding	Pfam	molecular function	4.4E-18
Wnt signaling pathway	PANTHER	biological process	1.1E-108