Gene Card
Best human hits
ILKAP; PPM1D; PPM1L
Species
Unique Gene ID
Phmamm.g00002947
Gene Model ID
Phmamm.CG.MTP2014.S90.g02947
Location
S90:134351..137781
Transcript Models and Sequences
Phmamm.CG.MTP2014.S90.g02947.01.t
Phmamm.CG.MTP2014.S90.g02947.02.t
AHC0AAA15YE05
Plate: Plate_15_E05
AHC0AAA19YG09
Plate: Plate_19_G09
AHC0AAA44YN14
Plate: Plate_44_N14
AHC0AAA61YP03
Plate: Plate_61_P03
AHC0AAA67YP11
Plate: Plate_67_P11
AHC0AAA70YM24
Plate: Plate_70_M24
AHC0AAA76YD12
Plate: Plate_76_D12
AHC0AAA76YI24
Plate: Plate_76_I24
AHC0AAA100YP02
Plate: Plate_100_P02
AHC0AAA102YK11
Plate: Plate_102_K11
AHC0AAA115YN11
Plate: Plate_115_N11
AHC0AAA126YA24
Plate: Plate_126_A24
AHC0AAA131YL11
Plate: Plate_131_L11
AHC0AAA143YL15
Plate: Plate_143_L15
AHC0AAA84YE06
Plate: Plate_84_E06
AHC0AAA84YI10
Plate: Plate_84_I10
AHC0AAA84YL06
Plate: Plate_84_L06
AHC0AAA85YI16
Plate: Plate_85_I16
AHC0AAA195YA24
Plate: Plate_195_A24
AHC0AAA196YD05
Plate: Plate_196_D05
AHC0AAA207YI20
Plate: Plate_207_I20
AHC0AAA230YE07
Plate: Plate_230_E07
AHC0AAA257YD16
Plate: Plate_257_D16
AHC0AAA267YO23
Plate: Plate_267_O23
n/a
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IPR Term | Analysis | Definition |
---|---|---|
PPM-type_phosphatase_dom | SMART | PPM-type phosphatase domain |
PPM-type_phosphatase_dom | CDD | PPM-type phosphatase domain |
PPM-type_phosphatase_dom | Pfam | PPM-type phosphatase domain |
PP2C | PANTHER | Protein phosphatase 2C family |
PPM-type_phosphatase_dom | ProSiteProfiles | PPM-type phosphatase domain |
PPM-type_dom_sf | Gene3D | PPM-type phosphatase domain superfamily |
PPM-type_dom_sf | SUPERFAMILY | PPM-type phosphatase domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
G2/M transition of mitotic cell cycle | Orthology | biological process |
catalytic activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endoplasmic reticulum membrane | Blast | cellular component |
cytosol | Orthology | cellular component |
transcription initiation from RNA polymerase II promoter | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
protein dephosphorylation | Orthology | biological process |
cell cycle | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
response to bacterium | Orthology | biological process |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
hydrolase activity | Orthology | molecular function |
cation binding | Orthology | molecular function |
metal ion binding | Orthology | molecular function |
extracellular exosome | Blast | cellular component |
DNA metabolic process | Orthology | biological process |
organelle organization | Orthology | biological process |
negative regulation of transcription, DNA-templated | Orthology | biological process |
cell communication | Orthology | biological process |
cellular response to stress | Orthology | biological process |
negative regulation of gene expression | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
G2/M transition of mitotic cell cycle | Hs | biological process |
catalytic activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
phosphoprotein phosphatase activity | Hs | molecular function |
protein serine/threonine phosphatase activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
DNA methylation | Hs | biological process |
chromatin silencing | Hs | biological process |
transcription initiation from RNA polymerase II promoter | Hs | biological process |
protein phosphorylation | Hs | biological process |
protein dephosphorylation | Hs | biological process |
cell cycle | Hs | biological process |
negative regulation of cell proliferation | Hs | biological process |
cellular response to starvation | Hs | biological process |
response to radiation | Hs | biological process |
response to bacterium | Hs | biological process |
hydrolase activity | Hs | molecular function |
peptidyl-threonine dephosphorylation | Hs | biological process |
cation binding | Hs | molecular function |
negative regulation of gene expression, epigenetic | Hs | biological process |
metal ion binding | Hs | molecular function |
mitogen-activated protein kinase binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
catalytic activity | Hs | molecular function | 319 | 2.65e-102 |
protein serine/threonine kinase activity | Hs | molecular function | 319 | 2.65e-102 |
phosphoprotein phosphatase activity | Hs | molecular function | 319 | 2.65e-102 |
protein serine/threonine phosphatase activity | Hs | molecular function | 319 | 2.65e-102 |
protein binding | Hs | molecular function | 319 | 2.65e-102 |
nucleus | Hs | cellular component | 319 | 2.65e-102 |
nucleoplasm | Hs | cellular component | 319 | 2.65e-102 |
cytoplasm | Hs | cellular component | 319 | 2.65e-102 |
endoplasmic reticulum membrane | Hs | cellular component | 97.8 | 3.95e-22 |
cytosol | Hs | cellular component | 319 | 2.65e-102 |
membrane | Hs | cellular component | 97.8 | 3.95e-22 |
integral component of membrane | Hs | cellular component | 97.8 | 3.95e-22 |
kinase activity | Hs | molecular function | 111 | 1.19e-26 |
hydrolase activity | Hs | molecular function | 319 | 2.65e-102 |
cation binding | Hs | molecular function | 319 | 2.65e-102 |
metal ion binding | Hs | molecular function | 319 | 2.65e-102 |
mitogen-activated protein kinase binding | Hs | molecular function | 319 | 2.65e-102 |
extracellular exosome | Hs | cellular component | 97.8 | 3.95e-22 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
catalytic activity | CDD | molecular function | 3.96775E-65 |
protein serine/threonine phosphatase activity | PANTHER | molecular function | 6.6E-144 |
protein dephosphorylation | PANTHER | biological process | 6.6E-144 |