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Gene Card
Best human hits
ANKFY1; HGS; ZFYVE28
Species
Unique Gene ID
Boleac.g00003821
Gene Model ID
Boleac.CG.SB_v3.S175.g03821
Location
S175:226406..228872
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
VHS_dom | ProSiteProfiles | VHS domain |
Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
Znf_FYVE | Pfam | FYVE zinc finger |
Ubi-bd_Hrs_VPS27 | PIRSF | Ubiquitin binding protein, Hrs/VPS27 |
Znf_FYVE | SMART | FYVE zinc finger |
ENTH_VHS | Gene3D | ENTH/VHS |
ENTH_VHS | SUPERFAMILY | ENTH/VHS |
HRS_helical | Pfam | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain |
VHS_dom | SMART | VHS domain |
UIM_dom | ProSiteProfiles | Ubiquitin interacting motif |
Znf_FYVE-rel | ProSiteProfiles | Zinc finger, FYVE-related |
VHS_dom | Pfam | VHS domain |
Znf_FYVE_PHD | SUPERFAMILY | Zinc finger, FYVE/PHD-type |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
protein binding | Hs | molecular function |
intracellular | Hs | cellular component |
cytoplasm | Hs | cellular component |
lysosome | Hs | cellular component |
endosome | Hs | cellular component |
early endosome | Hs | cellular component |
cytosol | Hs | cellular component |
protein targeting to lysosome | Hs | biological process |
intracellular protein transport | Hs | biological process |
signal transduction | Hs | biological process |
negative regulation of cell proliferation | Hs | biological process |
positive regulation of gene expression | Hs | biological process |
protein transport | Hs | biological process |
membrane | Hs | cellular component |
endosomal transport | Hs | biological process |
macroautophagy | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
negative regulation of angiogenesis | Hs | biological process |
protein deubiquitination | Hs | biological process |
protein domain specific binding | Hs | molecular function |
negative regulation of vascular endothelial growth factor receptor signaling pathway | Hs | biological process |
early endosome membrane | Hs | cellular component |
multivesicular body membrane | Hs | cellular component |
ESCRT-0 complex | Hs | cellular component |
multivesicular body assembly | Hs | biological process |
negative regulation of epidermal growth factor receptor signaling pathway | Hs | biological process |
regulation of protein catabolic process | Hs | biological process |
intracellular membrane-bounded organelle | Hs | cellular component |
regulation of MAP kinase activity | Hs | biological process |
ubiquitin-like protein ligase binding | Hs | molecular function |
negative regulation of JAK-STAT cascade | Hs | biological process |
metal ion binding | Hs | molecular function |
membrane organization | Hs | biological process |
extracellular exosome | Hs | cellular component |
protein localization to membrane | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
protein binding | Hs | molecular function | 544 | 0.0 |
intracellular | Hs | cellular component | 544 | 0.0 |
cytoplasm | Hs | cellular component | 544 | 0.0 |
lysosome | Hs | cellular component | 544 | 0.0 |
lysosomal membrane | Hs | cellular component | 80.9 | 1.88e-15 |
endosome | Hs | cellular component | 544 | 0.0 |
early endosome | Hs | cellular component | 544 | 0.0 |
cytosol | Hs | cellular component | 544 | 0.0 |
endosome membrane | Hs | cellular component | 80.9 | 1.88e-15 |
membrane | Hs | cellular component | 544 | 0.0 |
kinase activity | Hs | molecular function | 544 | 0.0 |
Rab GTPase binding | Hs | molecular function | 80.9 | 1.88e-15 |
protein domain specific binding | Hs | molecular function | 544 | 0.0 |
retromer complex | Hs | cellular component | 80.9 | 1.88e-15 |
early endosome membrane | Hs | cellular component | 544 | 0.0 |
phosphatidylinositol-3-phosphate binding | Hs | molecular function | 76.6 | 3.15e-14 |
multivesicular body membrane | Hs | cellular component | 544 | 0.0 |
ESCRT-0 complex | Hs | cellular component | 544 | 0.0 |
intracellular membrane-bounded organelle | Hs | cellular component | 544 | 0.0 |
macropinosome | Hs | cellular component | 80.9 | 1.88e-15 |
ubiquitin-like protein ligase binding | Hs | molecular function | 544 | 0.0 |
metal ion binding | Hs | molecular function | 544 | 0.0 |
extracellular exosome | Hs | cellular component | 544 | 0.0 |
phosphatidylinositol phosphate binding | Hs | molecular function | 80.9 | 1.88e-15 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
intracellular protein transport | Pfam | biological process | 3.6E-32 |
metal ion binding | SMART | molecular function | 1.0E-28 |