Gene Card
Best human hits
FURIN; PCSK1; PCSK2
Species
Unique Gene ID
Boleac.g00006521
Gene Model ID
Boleac.CG.SB_v3.S276.g06521
Location
S276:3318..13523
Transcript Models and Sequences
n/a
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Click here to see the tree inference method
InterPro
13 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Kexin/furin | CDD | Kexin/furin catalytic domain |
| P_dom | ProSiteProfiles | P domain |
| Galactose-bd-like_sf | Gene3D | Galactose-binding-like domain superfamily |
| Peptidase_S8_subtilisin-rel | PRINTS | Peptidase S8, subtilisin-related |
| Peptidase_S8/S53_dom_sf | SUPERFAMILY | Peptidase S8/S53 domain superfamily |
| Peptidase_S8/S53_dom_sf | Gene3D | Peptidase S8/S53 domain superfamily |
| P_dom | Pfam | P domain |
| S8_pro-domain | Pfam | Peptidase S8, pro-domain |
| Galactose-bd-like_sf | SUPERFAMILY | Galactose-binding-like domain superfamily |
| Peptidase_S8/S53_dom | Pfam | Peptidase S8/S53 domain |
| Peptidase_S8_Ser-AS | ProSitePatterns | Peptidase S8, subtilisin, Ser-active site |
| Peptidase_S8_His-AS | ProSitePatterns | Peptidase S8, subtilisin, His-active site |
| Peptidase_S8_Asp-AS | ProSitePatterns | Peptidase S8, subtilisin, Asp-active site |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
24 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| endopeptidase activity | Hs | molecular function |
| serine-type endopeptidase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| extracellular region | Hs | cellular component |
| extracellular space | Hs | cellular component |
| nucleus | Hs | cellular component |
| proteolysis | Hs | biological process |
| nervous system development | Hs | biological process |
| peptidase activity | Hs | molecular function |
| serine-type peptidase activity | Hs | molecular function |
| membrane | Hs | cellular component |
| protein processing | Hs | biological process |
| peptide hormone processing | Hs | biological process |
| protein autoprocessing | Hs | biological process |
| hydrolase activity | Hs | molecular function |
| insulin processing | Hs | biological process |
| transport vesicle | Hs | cellular component |
| secretory granule | Hs | cellular component |
| dendrite | Hs | cellular component |
| cytoplasmic vesicle | Hs | cellular component |
| secretory granule lumen | Hs | cellular component |
| neuronal cell body | Hs | cellular component |
| perikaryon | Hs | cellular component |
| intracellular membrane-bounded organelle | Hs | cellular component |
GO (Blast)
37 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 454 | 4.05e-151 |
| protease binding | Hs | molecular function | 454 | 4.05e-151 |
| endopeptidase activity | Hs | molecular function | 787 | 0.0 |
| serine-type endopeptidase activity | Hs | molecular function | 787 | 0.0 |
| serine-type endopeptidase inhibitor activity | Hs | molecular function | 454 | 4.05e-151 |
| protein binding | Hs | molecular function | 787 | 0.0 |
| extracellular region | Hs | cellular component | 787 | 0.0 |
| extracellular space | Hs | cellular component | 787 | 0.0 |
| nucleus | Hs | cellular component | 787 | 0.0 |
| endosome | Hs | cellular component | 454 | 4.05e-151 |
| endoplasmic reticulum | Hs | cellular component | 454 | 4.05e-151 |
| Golgi apparatus | Hs | cellular component | 454 | 4.05e-151 |
| Golgi lumen | Hs | cellular component | 454 | 4.05e-151 |
| trans-Golgi network | Hs | cellular component | 454 | 4.05e-151 |
| plasma membrane | Hs | cellular component | 454 | 4.05e-151 |
| peptidase activity | Hs | molecular function | 787 | 0.0 |
| serine-type peptidase activity | Hs | molecular function | 787 | 0.0 |
| cell surface | Hs | cellular component | 454 | 4.05e-151 |
| endosome membrane | Hs | cellular component | 454 | 4.05e-151 |
| membrane | Hs | cellular component | 787 | 0.0 |
| integral component of membrane | Hs | cellular component | 454 | 4.05e-151 |
| hydrolase activity | Hs | molecular function | 787 | 0.0 |
| transport vesicle | Hs | cellular component | 787 | 0.0 |
| trans-Golgi network transport vesicle | Hs | cellular component | 454 | 4.05e-151 |
| secretory granule | Hs | cellular component | 787 | 0.0 |
| dendrite | Hs | cellular component | 787 | 0.0 |
| cytoplasmic vesicle | Hs | cellular component | 787 | 0.0 |
| secretory granule lumen | Hs | cellular component | 787 | 0.0 |
| peptide binding | Hs | molecular function | 454 | 4.05e-151 |
| identical protein binding | Hs | molecular function | 450 | 5.52e-150 |
| neuronal cell body | Hs | cellular component | 787 | 0.0 |
| perikaryon | Hs | cellular component | 787 | 0.0 |
| intracellular membrane-bounded organelle | Hs | cellular component | 787 | 0.0 |
| membrane raft | Hs | cellular component | 454 | 4.05e-151 |
| metal ion binding | Hs | molecular function | 454 | 4.05e-151 |
| nerve growth factor binding | Hs | molecular function | 454 | 4.05e-151 |
| extracellular exosome | Hs | cellular component | 454 | 4.05e-151 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| serine-type endopeptidase activity | Gene3D | molecular function | 1.1E-84 |
| proteolysis | Gene3D | biological process | 1.1E-84 |
