Gene Card
Best human hits
AC008695.1; RAPGEF2; RAPGEF6
Species
Unique Gene ID
Boschl.g00063431
Gene Model ID
Boschl.CG.Botznik2013.chr10.g63431
Location
chr10:3604002..3613083
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
RapGEF2 | PANTHER | Rap guanine nucleotide exchange factor 2 |
RmlC-like_jellyroll | Gene3D | RmlC-like jelly roll fold |
cNMP-bd-like | SUPERFAMILY | Cyclic nucleotide-binding-like |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
signal transducer activity | Hs | molecular function | 70.1 | 2.47e-13 |
guanyl-nucleotide exchange factor activity | Hs | molecular function | 108 | 2.54e-26 |
Ras guanyl-nucleotide exchange factor activity | Hs | molecular function | 70.1 | 2.47e-13 |
GTPase activator activity | Hs | molecular function | 70.1 | 2.47e-13 |
calcium ion binding | Hs | molecular function | 70.1 | 2.47e-13 |
protein binding | Hs | molecular function | 108 | 2.54e-26 |
intracellular | Hs | cellular component | 108 | 2.54e-26 |
cytoplasm | Hs | cellular component | 108 | 2.54e-26 |
endosome | Hs | cellular component | 70.1 | 2.47e-13 |
late endosome | Hs | cellular component | 70.1 | 2.47e-13 |
centrosome | Hs | cellular component | 108 | 2.54e-26 |
cytosol | Hs | cellular component | 108 | 2.54e-26 |
plasma membrane | Hs | cellular component | 108 | 2.54e-26 |
integral component of plasma membrane | Hs | cellular component | 70.1 | 2.47e-13 |
cell-cell junction | Hs | cellular component | 70.1 | 2.47e-13 |
bicellular tight junction | Hs | cellular component | 70.1 | 2.47e-13 |
membrane | Hs | cellular component | 108 | 2.54e-26 |
apical plasma membrane | Hs | cellular component | 108 | 2.54e-26 |
Ras GTPase binding | Hs | molecular function | 108 | 2.54e-26 |
Rap guanyl-nucleotide exchange factor activity | Hs | molecular function | 70.1 | 2.47e-13 |
diacylglycerol binding | Hs | molecular function | 70.1 | 2.47e-13 |
cell junction | Hs | cellular component | 70.1 | 2.47e-13 |
endocytic vesicle | Hs | cellular component | 108 | 2.54e-26 |
PDZ domain binding | Hs | molecular function | 70.1 | 2.47e-13 |
cAMP binding | Hs | molecular function | 70.1 | 2.47e-13 |
GTP-dependent protein binding | Hs | molecular function | 108 | 2.54e-26 |
beta-1 adrenergic receptor binding | Hs | molecular function | 70.1 | 2.47e-13 |
macromolecular complex | Hs | cellular component | 70.1 | 2.47e-13 |
neuron projection | Hs | cellular component | 70.1 | 2.47e-13 |
neuronal cell body | Hs | cellular component | 70.1 | 2.47e-13 |
synapse | Hs | cellular component | 70.1 | 2.47e-13 |
perinuclear region of cytoplasm | Hs | cellular component | 70.1 | 2.47e-13 |
WW domain binding | Hs | molecular function | 70.1 | 2.47e-13 |
phosphatidic acid binding | Hs | molecular function | 108 | 2.54e-26 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
GTPase activator activity | PANTHER | molecular function | 1.6E-39 |
Rap guanyl-nucleotide exchange factor activity | PANTHER | molecular function | 1.6E-39 |
regulation of cell proliferation | PANTHER | biological process | 1.6E-39 |
positive regulation of GTPase activity | PANTHER | biological process | 1.6E-39 |