Aniseed - Gene card

Gene Card

Best human hits

AC008695.1; RAPGEF2; RAPGEF6

Species

B.schlosseri

Unique Gene ID

Boschl.g00063545

Gene Model ID

Boschl.CG.Botznik2013.chr10.g63545

Location

chr10:3807137..3808018

Transcript Models and Sequences

Boschl.CG.Botznik2013.chr10.g63545.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term	Analysis	Definition
RASGEF_cat_dom_sf	Gene3D	Ras guanine-nucleotide exchange factor catalytic domain superfamily
Ras_G-nucl-exch_fac_CS	ProSitePatterns	Ras guanine-nucleotide exchange factor, conserved site
RASGEF_cat_dom	ProSiteProfiles	Ras guanine-nucleotide exchange factors catalytic domain
Ras_GEF_dom_sf	SUPERFAMILY	Ras guanine nucleotide exchange factor domain superfamily
RASGEF_cat_dom	Pfam	Ras guanine-nucleotide exchange factors catalytic domain

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

74 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
MAPK cascade	Hs	biological process
blood vessel development	Hs	biological process
neuron migration	Hs	biological process
signal transducer activity	Hs	molecular function
guanyl-nucleotide exchange factor activity	Hs	molecular function
Ras guanyl-nucleotide exchange factor activity	Hs	molecular function
GTPase activator activity	Hs	molecular function
calcium ion binding	Hs	molecular function
protein binding	Hs	molecular function
intracellular	Hs	cellular component
cytoplasm	Hs	cellular component
endosome	Hs	cellular component
late endosome	Hs	cellular component
centrosome	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
cell-cell junction	Hs	cellular component
bicellular tight junction	Hs	cellular component
signal transduction	Hs	biological process
G-protein coupled receptor signaling pathway	Hs	biological process
neuropeptide signaling pathway	Hs	biological process
small GTPase mediated signal transduction	Hs	biological process
Ras protein signal transduction	Hs	biological process
multicellular organism development	Hs	biological process
nervous system development	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
positive regulation of neuron projection development	Hs	biological process
membrane	Hs	cellular component
apical plasma membrane	Hs	cellular component
Ras GTPase binding	Hs	molecular function
Rap guanyl-nucleotide exchange factor activity	Hs	molecular function
cAMP-mediated signaling	Hs	biological process
diacylglycerol binding	Hs	molecular function
ventricular system development	Hs	biological process
forebrain neuron development	Hs	biological process
microvillus assembly	Hs	biological process
cell junction	Hs	cellular component
endocytic vesicle	Hs	cellular component
cell differentiation	Hs	biological process
PDZ domain binding	Hs	molecular function
cAMP binding	Hs	molecular function
GTP-dependent protein binding	Hs	molecular function
neuron projection development	Hs	biological process
beta-1 adrenergic receptor binding	Hs	molecular function
positive regulation of protein binding	Hs	biological process
Rap protein signal transduction	Hs	biological process
macromolecular complex	Hs	cellular component
intracellular signal transduction	Hs	biological process
nerve growth factor signaling pathway	Hs	biological process
regulation of cell proliferation	Hs	biological process
neuron projection	Hs	cellular component
neuronal cell body	Hs	cellular component
regulation of GTPase activity	Hs	biological process
positive regulation of GTPase activity	Hs	biological process
positive regulation of cAMP-mediated signaling	Hs	biological process
synapse	Hs	cellular component
positive regulation of protein kinase activity	Hs	biological process
negative regulation of melanin biosynthetic process	Hs	biological process
regulation of synaptic plasticity	Hs	biological process
perinuclear region of cytoplasm	Hs	cellular component
WW domain binding	Hs	molecular function
negative regulation of dendrite morphogenesis	Hs	biological process
establishment of endothelial barrier	Hs	biological process
regulation of molecular function	Hs	biological process
phosphatidic acid binding	Hs	molecular function
positive regulation of ERK1 and ERK2 cascade	Hs	biological process
cellular response to cGMP	Hs	biological process
adenylate cyclase-activating adrenergic receptor signaling pathway	Hs	biological process
protein localization to plasma membrane	Hs	biological process
establishment of endothelial intestinal barrier	Hs	biological process
regulation of cell junction assembly	Hs	biological process
positive regulation of dendritic cell apoptotic process	Hs	biological process
positive regulation of neuron migration	Hs	biological process

GO (Blast)

34 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
signal transducer activity	Hs	molecular function	131	1.79e-36
guanyl-nucleotide exchange factor activity	Hs	molecular function	131	1.79e-36
Ras guanyl-nucleotide exchange factor activity	Hs	molecular function	131	1.79e-36
GTPase activator activity	Hs	molecular function	131	1.79e-36
calcium ion binding	Hs	molecular function	131	1.79e-36
protein binding	Hs	molecular function	131	1.79e-36
intracellular	Hs	cellular component	128	2.17e-35
cytoplasm	Hs	cellular component	131	1.79e-36
endosome	Hs	cellular component	131	1.79e-36
late endosome	Hs	cellular component	131	1.79e-36
centrosome	Hs	cellular component	128	2.11e-35
cytosol	Hs	cellular component	131	1.79e-36
plasma membrane	Hs	cellular component	131	1.79e-36
integral component of plasma membrane	Hs	cellular component	131	1.79e-36
cell-cell junction	Hs	cellular component	131	1.79e-36
bicellular tight junction	Hs	cellular component	131	1.79e-36
membrane	Hs	cellular component	131	1.79e-36
apical plasma membrane	Hs	cellular component	131	1.79e-36
Ras GTPase binding	Hs	molecular function	128	2.17e-35
Rap guanyl-nucleotide exchange factor activity	Hs	molecular function	131	1.79e-36
diacylglycerol binding	Hs	molecular function	131	1.79e-36
cell junction	Hs	cellular component	131	1.79e-36
endocytic vesicle	Hs	cellular component	131	1.79e-36
PDZ domain binding	Hs	molecular function	131	1.79e-36
cAMP binding	Hs	molecular function	131	1.79e-36
GTP-dependent protein binding	Hs	molecular function	128	2.17e-35
beta-1 adrenergic receptor binding	Hs	molecular function	131	1.79e-36
macromolecular complex	Hs	cellular component	131	1.79e-36
neuron projection	Hs	cellular component	131	1.79e-36
neuronal cell body	Hs	cellular component	131	1.79e-36
synapse	Hs	cellular component	131	1.79e-36
perinuclear region of cytoplasm	Hs	cellular component	131	1.79e-36
WW domain binding	Hs	molecular function	131	1.79e-36
phosphatidic acid binding	Hs	molecular function	131	1.79e-36

GO (InterProScan)

2 results

GO Term	Analysis	Type	e-value
guanyl-nucleotide exchange factor activity	Gene3D	molecular function	7.4E-33
small GTPase mediated signal transduction	Gene3D	biological process	7.4E-33