Aniseed - Gene card

Gene Card

Best human hits

SMAD3; SMAD4; SMAD5

Species

B.schlosseri

Unique Gene ID

Boschl.g00063821

Gene Model ID

Boschl.CG.Botznik2013.chr10.g63821

Location

chr10:2880976..2887651

Transcript Models and Sequences

Boschl.CG.Botznik2013.chr10.g63821.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term	Analysis	Definition
MAD_homology1_Dwarfin-type	Pfam	MAD homology 1, Dwarfin-type
SMAD-like_dom_sf	Gene3D	SMAD-like domain superfamily
SMAD_MH1_sf	Gene3D	SMAD MH1 domain superfamily
SMAD_MH1_sf	SUPERFAMILY	SMAD MH1 domain superfamily
Dwarfin	PANTHER	Dwarfin
MAD_homology1_Dwarfin-type	SMART	MAD homology 1, Dwarfin-type
MAD_homology_MH1	ProSiteProfiles	MAD homology, MH1
SMAD_dom_Dwarfin-type	SMART	SMAD domain, Dwarfin-type
SMAD_dom_Dwarfin-type	ProSiteProfiles	SMAD domain, Dwarfin-type
SMAD_dom_Dwarfin-type	Pfam	SMAD domain, Dwarfin-type
SMAD_FHA_dom_sf	SUPERFAMILY	SMAD/FHA domain superfamily

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

87 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
nuclear chromatin	Hs	cellular component
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
core promoter proximal region sequence-specific DNA binding	Hs	molecular function
transcription factor activity, transcription factor binding	Hs	molecular function
transcription factor activity, RNA polymerase II transcription factor binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
RNA polymerase II transcription factor binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function
ovarian follicle development	Hs	biological process
branching involved in ureteric bud morphogenesis	Hs	biological process
response to hypoxia	Hs	biological process
gastrulation with mouth forming second	Hs	biological process
kidney development	Hs	biological process
atrioventricular valve formation	Hs	biological process
DNA binding	Hs	molecular function
chromatin binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
protein binding	Hs	molecular function
collagen binding	Hs	molecular function
intracellular	Hs	cellular component
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
transcription factor complex	Hs	cellular component
cytoplasm	Hs	cellular component
centrosome	Hs	cellular component
cytosol	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
cellular iron ion homeostasis	Hs	biological process
transforming growth factor beta receptor signaling pathway	Hs	biological process
spermatogenesis	Hs	biological process
single fertilization	Hs	biological process
gastrulation	Hs	biological process
axon guidance	Hs	biological process
endoderm development	Hs	biological process
mesoderm development	Hs	biological process
cell proliferation	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
male gonad development	Hs	biological process
female gonad development	Hs	biological process
anterior/posterior pattern specification	Hs	biological process
positive regulation of epithelial to mesenchymal transition	Hs	biological process
positive regulation of pathway-restricted SMAD protein phosphorylation	Hs	biological process
neural crest cell differentiation	Hs	biological process
protein deubiquitination	Hs	biological process
regulation of transforming growth factor beta receptor signaling pathway	Hs	biological process
negative regulation of cell growth	Hs	biological process
BMP signaling pathway	Hs	biological process
positive regulation of transforming growth factor beta receptor signaling pathway	Hs	biological process
positive regulation of BMP signaling pathway	Hs	biological process
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity	Hs	molecular function
activin responsive factor complex	Hs	cellular component
somite rostral/caudal axis specification	Hs	biological process
somatic stem cell population maintenance	Hs	biological process
intracellular signal transduction	Hs	biological process
atrioventricular canal development	Hs	biological process
regulation of cell proliferation	Hs	biological process
identical protein binding	Hs	molecular function
protein homodimerization activity	Hs	molecular function
sulfate binding	Hs	molecular function
sequence-specific DNA binding	Hs	molecular function
transcription regulatory region DNA binding	Hs	molecular function
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
metal ion binding	Hs	molecular function
protein heterodimerization activity	Hs	molecular function
developmental growth	Hs	biological process
neuron fate commitment	Hs	biological process
tissue morphogenesis	Hs	biological process
formation of anatomical boundary	Hs	biological process
positive regulation of histone H3-K4 methylation	Hs	biological process
palate development	Hs	biological process
uterus development	Hs	biological process
SMAD protein signal transduction	Hs	biological process
negative regulation of cell death	Hs	biological process
endocardial cell differentiation	Hs	biological process
protein homotrimerization	Hs	biological process
negative regulation of ERK1 and ERK2 cascade	Hs	biological process
I-SMAD binding	Hs	molecular function
R-SMAD binding	Hs	molecular function
SMAD protein complex	Hs	cellular component
RNA polymerase II transcription factor complex	Hs	cellular component

GO (Blast)

64 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nuclear chromatin	Hs	cellular component	454	5.56e-158
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function	454	5.56e-158
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	454	5.56e-158
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	454	5.56e-158
transcription factor activity, RNA polymerase II core promoter sequence-specific	Hs	molecular function	213	3.23e-65
core promoter proximal region sequence-specific DNA binding	Hs	molecular function	454	5.56e-158
transcription factor activity, transcription factor binding	Hs	molecular function	454	5.56e-158
transcription factor activity, RNA polymerase II transcription factor binding	Hs	molecular function	454	5.56e-158
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	454	5.56e-158
RNA polymerase II transcription factor binding	Hs	molecular function	454	5.56e-158
RNA polymerase II activating transcription factor binding	Hs	molecular function	213	3.23e-65
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function	454	5.56e-158
DNA binding	Hs	molecular function	454	5.56e-158
chromatin binding	Hs	molecular function	454	5.56e-158
double-stranded DNA binding	Hs	molecular function	213	3.23e-65
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	454	5.56e-158
signal transducer activity, downstream of receptor	Hs	molecular function	201	2.34e-60
transforming growth factor beta receptor binding	Hs	molecular function	213	3.23e-65
protein binding	Hs	molecular function	454	5.56e-158
collagen binding	Hs	molecular function	454	5.56e-158
intracellular	Hs	cellular component	454	5.56e-158
nucleus	Hs	cellular component	454	5.56e-158
nuclear inner membrane	Hs	cellular component	213	3.23e-65
nucleoplasm	Hs	cellular component	454	5.56e-158
transcription factor complex	Hs	cellular component	454	5.56e-158
cytoplasm	Hs	cellular component	454	5.56e-158
centrosome	Hs	cellular component	454	5.56e-158
cytosol	Hs	cellular component	454	5.56e-158
plasma membrane	Hs	cellular component	213	3.23e-65
beta-catenin binding	Hs	molecular function	213	3.23e-65
transcription factor binding	Hs	molecular function	213	3.23e-65
zinc ion binding	Hs	molecular function	213	3.23e-65
integral component of membrane	Hs	cellular component	201	2.34e-60
DEAD/H-box RNA helicase binding	Hs	molecular function	213	3.23e-65
enzyme binding	Hs	molecular function	213	3.23e-65
protein kinase binding	Hs	molecular function	213	3.23e-65
phosphatase binding	Hs	molecular function	213	3.23e-65
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity	Hs	molecular function	454	5.56e-158
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	Hs	molecular function	213	3.23e-65
chromatin DNA binding	Hs	molecular function	213	3.23e-65
ubiquitin protein ligase binding	Hs	molecular function	213	3.23e-65
mineralocorticoid receptor binding	Hs	molecular function	213	3.23e-65
activin responsive factor complex	Hs	cellular component	454	5.56e-158
macromolecular complex	Hs	cellular component	201	2.34e-60
glucocorticoid receptor binding	Hs	molecular function	213	3.23e-65
enhancer binding	Hs	molecular function	213	3.23e-65
identical protein binding	Hs	molecular function	454	5.56e-158
protein homodimerization activity	Hs	molecular function	454	5.56e-158
ubiquitin binding	Hs	molecular function	213	3.23e-65
sulfate binding	Hs	molecular function	454	5.56e-158
receptor complex	Hs	cellular component	213	3.23e-65
bHLH transcription factor binding	Hs	molecular function	213	3.23e-65
sequence-specific DNA binding	Hs	molecular function	454	5.56e-158
transcription regulatory region DNA binding	Hs	molecular function	454	5.56e-158
SMAD binding	Hs	molecular function	213	3.23e-65
metal ion binding	Hs	molecular function	454	5.56e-158
protein heterodimerization activity	Hs	molecular function	454	5.56e-158
co-SMAD binding	Hs	molecular function	213	3.23e-65
I-SMAD binding	Hs	molecular function	454	5.56e-158
R-SMAD binding	Hs	molecular function	454	5.56e-158
primary miRNA binding	Hs	molecular function	213	3.23e-65
SMAD protein complex	Hs	cellular component	454	5.56e-158
SMAD2-SMAD3 protein complex	Hs	cellular component	213	3.23e-65
RNA polymerase II transcription factor complex	Hs	cellular component	454	5.56e-158

GO (InterProScan)

6 results

GO Term	Analysis	Type	e-value
transcription factor activity, sequence-specific DNA binding	ProSiteProfiles	molecular function	35.156
protein binding	SUPERFAMILY	molecular function	1.8E-50
intracellular	PANTHER	cellular component	6.0E-164
transcription factor complex	ProSiteProfiles	cellular component	35.156
regulation of transcription, DNA-templated	PANTHER	biological process	6.0E-164
transforming growth factor beta receptor signaling pathway	Gene3D	biological process	9.9E-56