Gene Card
Best human hits
DHTKD1; OGDH; OGDHL
Species
Unique Gene ID
Boschl.g00066045
Gene Model ID
Boschl.CG.Botznik2013.chr10.g66045
Location
chr10:2679849..2684455
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
5 results
| IPR Term | Analysis | Definition |
|---|---|---|
| KGD_C | Pfam | Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal |
| Transketolase-like_Pyr-bd | SMART | Transketolase-like, pyrimidine-binding domain |
| 2oxoglutarate_DH_E1 | PANTHER | 2-oxoglutarate dehydrogenase E1 component |
| THDP-binding | SUPERFAMILY | Thiamin diphosphate-binding fold |
| Transketolase-like_Pyr-bd | Pfam | Transketolase-like, pyrimidine-binding domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
24 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| oxoglutarate dehydrogenase (succinyl-transferring) activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| mitochondrion | Hs | cellular component |
| mitochondrial matrix | Hs | cellular component |
| generation of precursor metabolites and energy | Hs | biological process |
| glycolytic process | Hs | biological process |
| tricarboxylic acid cycle | Hs | biological process |
| 2-oxoglutarate metabolic process | Hs | biological process |
| succinyl-CoA metabolic process | Hs | biological process |
| NADH metabolic process | Hs | biological process |
| metabolic process | Hs | biological process |
| oxidoreductase activity | Hs | molecular function |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function |
| cerebellar cortex development | Hs | biological process |
| thalamus development | Hs | biological process |
| thiamine pyrophosphate binding | Hs | molecular function |
| heat shock protein binding | Hs | molecular function |
| mitochondrial membrane | Hs | cellular component |
| oxoglutarate dehydrogenase (NAD+) activity | Hs | molecular function |
| oxoglutarate dehydrogenase complex | Hs | cellular component |
| metal ion binding | Hs | molecular function |
| chaperone binding | Hs | molecular function |
| oxidation-reduction process | Hs | biological process |
GO (Blast)
14 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| oxoglutarate dehydrogenase (succinyl-transferring) activity | Hs | molecular function | 648 | 0.0 |
| protein binding | Hs | molecular function | 628 | 0.0 |
| nucleus | Hs | cellular component | 648 | 0.0 |
| mitochondrion | Hs | cellular component | 648 | 0.0 |
| mitochondrial matrix | Hs | cellular component | 648 | 0.0 |
| oxidoreductase activity | Hs | molecular function | 648 | 0.0 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function | 648 | 0.0 |
| thiamine pyrophosphate binding | Hs | molecular function | 648 | 0.0 |
| heat shock protein binding | Hs | molecular function | 648 | 0.0 |
| mitochondrial membrane | Hs | cellular component | 648 | 0.0 |
| oxoglutarate dehydrogenase (NAD+) activity | Hs | molecular function | 648 | 0.0 |
| oxoglutarate dehydrogenase complex | Hs | cellular component | 648 | 0.0 |
| metal ion binding | Hs | molecular function | 648 | 0.0 |
| chaperone binding | Hs | molecular function | 648 | 0.0 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| oxoglutarate dehydrogenase (succinyl-transferring) activity | PANTHER | molecular function | 9.8E-226 |
| tricarboxylic acid cycle | PANTHER | biological process | 9.8E-226 |
| thiamine pyrophosphate binding | PANTHER | molecular function | 9.8E-226 |
| oxidation-reduction process | PANTHER | biological process | 9.8E-226 |
