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Gene Card

Best human hits

CUL1; CUL2; CUL3

Species

B.schlosseri

Unique Gene ID

Boschl.g00049777

Gene Model ID

Boschl.CG.Botznik2013.chr2.g49777

Location

chr2:3718252..3730216

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chr2.g49777.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
Cullin_CS ProSitePatterns Cullin, conserved site
WH-like_DNA-bd_sf Gene3D Winged helix-like DNA-binding domain superfamily
Cullin_homology_sf SUPERFAMILY Cullin homology domain superfamily
Cullin_homology SMART Cullin homology domain
Cullin_neddylation_domain Pfam Cullin protein, neddylation domain
Cullin_neddylation_domain SMART Cullin protein, neddylation domain
Cullin_repeat-like_dom_sf SUPERFAMILY Cullin repeat-like-containing domain superfamily
Cullin_N Pfam Cullin, N-terminal
Cullin_homology ProSiteProfiles Cullin homology domain
WH_DNA-bd_sf SUPERFAMILY Winged helix DNA-binding domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

34 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G1/S transition of mitotic cell cycle Hs biological process
G2/M transition of mitotic cell cycle Hs biological process
protein polyubiquitination Hs biological process
ubiquitin-protein transferase activity Hs molecular function
protein binding Hs molecular function
nucleoplasm Hs cellular component
cytosol Hs cellular component
ubiquitin-dependent protein catabolic process Hs biological process
protein monoubiquitination Hs biological process
cellular iron ion homeostasis Hs biological process
apoptotic process Hs biological process
cell cycle arrest Hs biological process
cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
animal organ morphogenesis Hs biological process
SCF complex assembly Hs biological process
negative regulation of G2/M transition of mitotic cell cycle Hs biological process
viral process Hs biological process
Wnt signaling pathway Hs biological process
protein ubiquitination Hs biological process
SCF ubiquitin ligase complex Hs cellular component
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Hs biological process
cullin-RING ubiquitin ligase complex Hs cellular component
ubiquitin protein ligase binding Hs molecular function
NIK/NF-kappaB signaling Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
post-translational protein modification Hs biological process
T cell receptor signaling pathway Hs biological process
stress-activated MAPK cascade Hs biological process
ubiquitin protein ligase activity Hs molecular function
interleukin-1-mediated signaling pathway Hs biological process
intrinsic apoptotic signaling pathway Hs biological process
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component

GO (Blast)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
Golgi membrane Hs cellular component 338 1.91e-105
ubiquitin-protein transferase activity Hs molecular function 1021 0.0
Notch binding Hs molecular function 338 1.91e-105
protein binding Hs molecular function 1021 0.0
nucleus Hs cellular component 338 1.91e-105
nucleoplasm Hs cellular component 1021 0.0
nucleolus Hs cellular component 449 6.33e-148
cytoplasm Hs cellular component 338 1.91e-105
Golgi apparatus Hs cellular component 338 1.91e-105
polar microtubule Hs cellular component 338 1.91e-105
cytosol Hs cellular component 1021 0.0
membrane Hs cellular component 338 1.91e-105
SCF ubiquitin ligase complex Hs cellular component 1021 0.0
cyclin binding Hs molecular function 338 1.91e-105
VCB complex Hs cellular component 449 6.33e-148
POZ domain binding Hs molecular function 338 1.91e-105
cullin-RING ubiquitin ligase complex Hs cellular component 1021 0.0
Cul2-RING ubiquitin ligase complex Hs cellular component 449 6.33e-148
Cul3-RING ubiquitin ligase complex Hs cellular component 338 1.91e-105
ubiquitin protein ligase binding Hs molecular function 1021 0.0
sperm flagellum Hs cellular component 338 1.91e-105
protein homodimerization activity Hs molecular function 338 1.91e-105
protein heterodimerization activity Hs molecular function 338 1.91e-105
ubiquitin protein ligase activity Hs molecular function 1021 0.0
extracellular exosome Hs cellular component 338 1.91e-105
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component 1021 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ubiquitin-dependent protein catabolic process Pfam biological process 2.5E-175
cullin-RING ubiquitin ligase complex ProSitePatterns cellular component
ubiquitin protein ligase binding Pfam molecular function 2.5E-175

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