Gene Card
Best human hits
BMP7; LEFTY1; LEFTY2
Species
Unique Gene ID
Boschl.g00044248
Gene Model ID
Boschl.CG.Botznik2013.chr6.g44248
Location
chr6:6705282..6710494
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
9 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Cystine-knot_cytokine | Gene3D | Cystine-knot cytokine |
| TGF-b_C | Pfam | Transforming growth factor-beta, C-terminal |
| TGFb_CS | ProSitePatterns | Transforming growth factor beta, conserved site |
| TGF-b_C | SMART | Transforming growth factor-beta, C-terminal |
| TGF-b_C | ProSiteProfiles | Transforming growth factor-beta, C-terminal |
| LRDF | PIRSF | Left- Right determination factor |
| Cystine-knot_cytokine | SUPERFAMILY | Cystine-knot cytokine |
| TGF-beta-rel | PANTHER | Transforming growth factor-beta-related |
| TGF-b_propeptide | Pfam | TGF-beta, propeptide |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
21 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| negative regulation of transcription from RNA polymerase II promoter | Hs | biological process |
| platelet degranulation | Hs | biological process |
| heart morphogenesis | Hs | biological process |
| cytokine activity | Hs | molecular function |
| transforming growth factor beta receptor binding | Hs | molecular function |
| extracellular region | Hs | cellular component |
| extracellular space | Hs | cellular component |
| transforming growth factor beta receptor signaling pathway | Hs | biological process |
| multicellular organism development | Hs | biological process |
| determination of left/right symmetry | Hs | biological process |
| growth factor activity | Hs | molecular function |
| regulation of receptor activity | Hs | biological process |
| positive regulation of pathway-restricted SMAD protein phosphorylation | Hs | biological process |
| cell growth | Hs | biological process |
| BMP signaling pathway | Hs | biological process |
| extracellular matrix | Hs | cellular component |
| platelet alpha granule lumen | Hs | cellular component |
| regulation of apoptotic process | Hs | biological process |
| regulation of MAPK cascade | Hs | biological process |
| cell development | Hs | biological process |
| SMAD protein signal transduction | Hs | biological process |
GO (Blast)
11 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| cytokine activity | Hs | molecular function | 142 | 1.48e-38 |
| transforming growth factor beta receptor binding | Hs | molecular function | 142 | 1.48e-38 |
| protein binding | Hs | molecular function | 81.3 | 1.23e-16 |
| extracellular region | Hs | cellular component | 142 | 1.48e-38 |
| extracellular space | Hs | cellular component | 142 | 1.48e-38 |
| growth factor activity | Hs | molecular function | 142 | 1.48e-38 |
| heparin binding | Hs | molecular function | 81.3 | 1.23e-16 |
| extracellular matrix | Hs | cellular component | 142 | 1.48e-38 |
| platelet alpha granule lumen | Hs | cellular component | 142 | 1.48e-38 |
| vesicle | Hs | cellular component | 81.3 | 1.23e-16 |
| BMP receptor binding | Hs | molecular function | 81.3 | 1.23e-16 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| transforming growth factor beta receptor binding | PIRSF | molecular function | 5.4E-115 |
| growth factor activity | Pfam | molecular function | 1.4E-11 |
| cell growth | PIRSF | biological process | 5.4E-115 |
