Gene Card
Best human hits
ADAMTS1; ADAMTS15; ADAMTS8
Species
Unique Gene ID
Boschl.g00054615
Gene Model ID
Boschl.CG.Botznik2013.chr6.g54615
Location
chr6:3763104..3768744
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
4 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Peptidase_M12B | Pfam | Peptidase M12B, ADAM/reprolysin |
| MetalloPept_cat_dom_sf | Gene3D | Metallopeptidase, catalytic domain superfamily |
| Peptidase_M12B | ProSiteProfiles | Peptidase M12B, ADAM/reprolysin |
| Peptidase_M12B_N | Pfam | Peptidase M12B, propeptide |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
33 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| kidney development | Hs | biological process |
| endopeptidase activity | Hs | molecular function |
| metalloendopeptidase activity | Hs | molecular function |
| integrin binding | Hs | molecular function |
| extracellular region | Hs | cellular component |
| proteinaceous extracellular matrix | Hs | cellular component |
| basement membrane | Hs | cellular component |
| extracellular space | Hs | cellular component |
| proteolysis | Hs | biological process |
| integrin-mediated signaling pathway | Hs | biological process |
| heparin binding | Hs | molecular function |
| peptidase activity | Hs | molecular function |
| metallopeptidase activity | Hs | molecular function |
| zinc ion binding | Hs | molecular function |
| negative regulation of cell proliferation | Hs | biological process |
| low-affinity phosphate transmembrane transporter activity | Hs | molecular function |
| cell surface | Hs | cellular component |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| hydrolase activity | Hs | molecular function |
| extracellular matrix | Hs | cellular component |
| cytoplasmic vesicle | Hs | cellular component |
| phosphate ion transmembrane transport | Hs | biological process |
| metal ion binding | Hs | molecular function |
| extracellular matrix binding | Hs | molecular function |
| heart trabecula formation | Hs | biological process |
| skeletal system development | Hs | biological process |
| protease binding | Hs | molecular function |
| protein binding | Hs | molecular function |
| endoplasmic reticulum lumen | Hs | cellular component |
| nuclear speck | Hs | cellular component |
| protein O-linked fucosylation | Hs | biological process |
| defense response to bacterium | Hs | biological process |
GO (Blast)
20 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| endopeptidase activity | Hs | molecular function | 313 | 1.10e-96 |
| metalloendopeptidase activity | Hs | molecular function | 328 | 3.48e-102 |
| integrin binding | Hs | molecular function | 291 | 7.19e-89 |
| extracellular region | Hs | cellular component | 328 | 3.48e-102 |
| proteinaceous extracellular matrix | Hs | cellular component | 328 | 3.48e-102 |
| basement membrane | Hs | cellular component | 328 | 3.48e-102 |
| extracellular space | Hs | cellular component | 313 | 1.10e-96 |
| heparin binding | Hs | molecular function | 328 | 3.48e-102 |
| peptidase activity | Hs | molecular function | 328 | 3.48e-102 |
| metallopeptidase activity | Hs | molecular function | 328 | 3.48e-102 |
| zinc ion binding | Hs | molecular function | 328 | 3.48e-102 |
| low-affinity phosphate transmembrane transporter activity | Hs | molecular function | 291 | 7.19e-89 |
| cell surface | Hs | cellular component | 313 | 1.10e-96 |
| membrane | Hs | cellular component | 328 | 3.48e-102 |
| integral component of membrane | Hs | cellular component | 328 | 3.48e-102 |
| hydrolase activity | Hs | molecular function | 328 | 3.48e-102 |
| extracellular matrix | Hs | cellular component | 291 | 7.19e-89 |
| cytoplasmic vesicle | Hs | cellular component | 328 | 3.48e-102 |
| metal ion binding | Hs | molecular function | 328 | 3.48e-102 |
| extracellular matrix binding | Hs | molecular function | 313 | 1.10e-96 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| metalloendopeptidase activity | Pfam | molecular function | 1.6E-25 |
| proteolysis | Pfam | biological process | 1.6E-25 |
| metallopeptidase activity | Gene3D | molecular function | 1.2E-84 |
