Aniseed - Gene card

Gene Card

Best human hits

HMGB1; HMGB2; HMGB3

Species

B.schlosseri

Unique Gene ID

Boschl.g00060981

Gene Model ID

Boschl.CG.Botznik2013.chr6.g60981

Location

chr6:2880899..2881658

Transcript Models and Sequences

Boschl.CG.Botznik2013.chr6.g60981.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term	Analysis	Definition
HMG_box_dom_sf	SUPERFAMILY	High mobility group box domain superfamily
HMG_box_dom_sf	Gene3D	High mobility group box domain superfamily
HMG_box_dom	ProSiteProfiles	High mobility group box domain
HMG_box_dom	Pfam	High mobility group box domain
HMG_box_dom	SMART	High mobility group box domain

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

125 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
four-way junction DNA binding	Hs	molecular function
bubble DNA binding	Hs	molecular function
nuclear chromatin	Hs	cellular component
condensed chromosome	Hs	cellular component
enhancer sequence-specific DNA binding	Hs	molecular function
lipopolysaccharide binding	Hs	molecular function
eye development	Hs	biological process
phosphatidylserine binding	Hs	molecular function
positive regulation of protein phosphorylation	Hs	biological process
endothelial cell proliferation	Hs	biological process
positive regulation of endothelial cell proliferation	Hs	biological process
activation of innate immune response	Hs	biological process
toll-like receptor signaling pathway	Hs	biological process
adaptive immune response	Hs	biological process
macrophage activation involved in immune response	Hs	biological process
immune system process	Hs	biological process
dendritic cell chemotaxis	Hs	biological process
DNA binding	Hs	molecular function
damaged DNA binding	Hs	molecular function
double-stranded DNA binding	Hs	molecular function
single-stranded DNA binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
RNA binding	Hs	molecular function
double-stranded RNA binding	Hs	molecular function
single-stranded RNA binding	Hs	molecular function
cytokine activity	Hs	molecular function
integrin binding	Hs	molecular function
protein binding	Hs	molecular function
extracellular region	Hs	cellular component
extracellular space	Hs	cellular component
cell	Hs	cellular component
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
chromosome	Hs	cellular component
nucleolus	Hs	cellular component
cytoplasm	Hs	cellular component
endosome	Hs	cellular component
early endosome	Hs	cellular component
endoplasmic reticulum-Golgi intermediate compartment	Hs	cellular component
plasma membrane	Hs	cellular component
DNA topological change	Hs	biological process
DNA repair	Hs	biological process
base-excision repair	Hs	biological process
apoptotic DNA fragmentation	Hs	biological process
DNA recombination	Hs	biological process
chromatin organization	Hs	biological process
nucleosome assembly	Hs	biological process
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
autophagy	Hs	biological process
chemotaxis	Hs	biological process
inflammatory response	Hs	biological process
cellular response to DNA damage stimulus	Hs	biological process
positive regulation of cytosolic calcium ion concentration	Hs	biological process
multicellular organism development	Hs	biological process
spermatogenesis	Hs	biological process
spermatid nucleus differentiation	Hs	biological process
transcription factor binding	Hs	molecular function
drug binding	Hs	molecular function
DNA binding, bending	Hs	molecular function
male gonad development	Hs	biological process
cell surface	Hs	cellular component
regulation of receptor activity	Hs	biological process
regulation of autophagy	Hs	biological process
positive regulation of gene expression	Hs	biological process
negative regulation of gene expression	Hs	biological process
calcium-dependent protein kinase regulator activity	Hs	molecular function
membrane	Hs	cellular component
lyase activity	Hs	molecular function
transcriptional repressor complex	Hs	cellular component
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	Hs	biological process
protein domain specific binding	Hs	molecular function
C-X-C chemokine binding	Hs	molecular function
protein kinase activator activity	Hs	molecular function
lung development	Hs	biological process
neuron projection development	Hs	biological process
chromatin assembly	Hs	biological process
response to lipopolysaccharide	Hs	biological process
macromolecular complex	Hs	cellular component
V(D)J recombination	Hs	biological process
secretory granule lumen	Hs	cellular component
endothelial cell chemotaxis	Hs	biological process
alphav-beta3 integrin-HMGB1 complex	Hs	cellular component
chemoattractant activity	Hs	molecular function
response to drug	Hs	biological process
neuron projection	Hs	cellular component
positive regulation of apoptotic process	Hs	biological process
apoptotic cell clearance	Hs	biological process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Hs	biological process
positive regulation of DNA binding	Hs	biological process
positive regulation of MAPK cascade	Hs	biological process
negative regulation of blood vessel endothelial cell migration	Hs	biological process
transcription regulatory region DNA binding	Hs	molecular function
non-sequence-specific DNA binding, bending	Hs	molecular function
innate immune response	Hs	biological process
positive regulation of innate immune response	Hs	biological process
positive regulation of myeloid cell differentiation	Hs	biological process
positive regulation of erythrocyte differentiation	Hs	biological process
positive regulation of glycogen catabolic process	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
positive regulation of JNK cascade	Hs	biological process
perinuclear region of cytoplasm	Hs	cellular component
response to steroid hormone	Hs	biological process
regulation of neurogenesis	Hs	biological process
RAGE receptor binding	Hs	molecular function
defense response to Gram-negative bacterium	Hs	biological process
defense response to Gram-positive bacterium	Hs	biological process
positive chemotaxis	Hs	biological process
DNA ligation involved in DNA repair	Hs	biological process
response to glucocorticoid	Hs	biological process
cell chemotaxis	Hs	biological process
DNA polymerase binding	Hs	molecular function
positive regulation of ERK1 and ERK2 cascade	Hs	biological process
repressing transcription factor binding	Hs	molecular function
cellular response to lipopolysaccharide	Hs	biological process
regulation of stem cell proliferation	Hs	biological process
positive regulation of wound healing	Hs	biological process
supercoiled DNA binding	Hs	molecular function
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Hs	biological process
positive regulation of sprouting angiogenesis	Hs	biological process
ficolin-1-rich granule lumen	Hs	cellular component

GO (Blast)

54 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
four-way junction DNA binding	Hs	molecular function	169	1.73e-53
bubble DNA binding	Hs	molecular function	169	1.73e-53
nuclear chromatin	Hs	cellular component	165	7.65e-52
condensed chromosome	Hs	cellular component	169	1.73e-53
enhancer sequence-specific DNA binding	Hs	molecular function	165	7.65e-52
lipopolysaccharide binding	Hs	molecular function	169	1.73e-53
phosphatidylserine binding	Hs	molecular function	169	1.73e-53
DNA binding	Hs	molecular function	169	1.73e-53
damaged DNA binding	Hs	molecular function	169	1.73e-53
double-stranded DNA binding	Hs	molecular function	169	1.73e-53
single-stranded DNA binding	Hs	molecular function	169	1.73e-53
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	169	1.73e-53
RNA binding	Hs	molecular function	169	1.73e-53
double-stranded RNA binding	Hs	molecular function	169	1.73e-53
single-stranded RNA binding	Hs	molecular function	169	1.73e-53
cytokine activity	Hs	molecular function	169	1.73e-53
integrin binding	Hs	molecular function	169	1.73e-53
protein binding	Hs	molecular function	169	1.73e-53
extracellular region	Hs	cellular component	169	1.73e-53
extracellular space	Hs	cellular component	169	1.73e-53
cell	Hs	cellular component	165	7.65e-52
nucleus	Hs	cellular component	169	1.73e-53
nucleoplasm	Hs	cellular component	169	1.73e-53
chromosome	Hs	cellular component	169	1.73e-53
nucleolus	Hs	cellular component	165	7.65e-52
cytoplasm	Hs	cellular component	169	1.73e-53
endosome	Hs	cellular component	169	1.73e-53
early endosome	Hs	cellular component	169	1.73e-53
endoplasmic reticulum-Golgi intermediate compartment	Hs	cellular component	169	1.73e-53
plasma membrane	Hs	cellular component	169	1.73e-53
transcription factor binding	Hs	molecular function	169	1.73e-53
drug binding	Hs	molecular function	165	7.65e-52
DNA binding, bending	Hs	molecular function	169	1.73e-53
cell surface	Hs	cellular component	169	1.73e-53
calcium-dependent protein kinase regulator activity	Hs	molecular function	169	1.73e-53
membrane	Hs	cellular component	169	1.73e-53
lyase activity	Hs	molecular function	169	1.73e-53
transcriptional repressor complex	Hs	cellular component	169	1.73e-53
protein domain specific binding	Hs	molecular function	165	7.65e-52
C-X-C chemokine binding	Hs	molecular function	169	1.73e-53
protein kinase activator activity	Hs	molecular function	169	1.73e-53
macromolecular complex	Hs	cellular component	165	7.65e-52
secretory granule lumen	Hs	cellular component	169	1.73e-53
alphav-beta3 integrin-HMGB1 complex	Hs	cellular component	169	1.73e-53
chemoattractant activity	Hs	molecular function	169	1.73e-53
neuron projection	Hs	cellular component	169	1.73e-53
transcription regulatory region DNA binding	Hs	molecular function	165	7.65e-52
non-sequence-specific DNA binding, bending	Hs	molecular function	165	7.65e-52
perinuclear region of cytoplasm	Hs	cellular component	165	7.65e-52
RAGE receptor binding	Hs	molecular function	169	1.73e-53
DNA polymerase binding	Hs	molecular function	169	1.73e-53
repressing transcription factor binding	Hs	molecular function	169	1.73e-53
supercoiled DNA binding	Hs	molecular function	169	1.73e-53
ficolin-1-rich granule lumen	Hs	cellular component	169	1.73e-53

GO (InterProScan)

No result

GO Term	Analysis	Type	e-value