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Gene Card

Best human hits

DHH; IHH; SHH

Species

B.schlosseri

Unique Gene ID

Boschl.g00053297

Gene Model ID

Boschl.CG.Botznik2013.chr9.g53297

Location

chr9:13530824..13550818

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chr9.g53297.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

9 results

IPR Term Analysis Definition
Hint_dom_C SMART Hint domain C-terminal
Hedgehog PRINTS Hedgehog protein
Hint_dom_sf SUPERFAMILY Hint domain superfamily
Hedgehog_sig/DD-Pept_Zn-bd_sf Gene3D Hedgehog signalling/DD-peptidase zinc-binding domain superfamily
Hedgehog_signalling_dom Pfam Hedgehog, N-terminal signalling domain
Hint_dom Pfam Hedgehog protein, Hint domain
Hint_dom_N SMART Hint domain N-terminal
Intein_N ProSiteProfiles Intein N-terminal splicing region
Hedgehog_sig/DD-Pept_Zn-bd_sf SUPERFAMILY Hedgehog signalling/DD-peptidase zinc-binding domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

162 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
skeletal system development Hs biological process
ossification Hs biological process
angiogenesis Hs biological process
branching involved in blood vessel morphogenesis Hs biological process
vasculogenesis Hs biological process
osteoblast differentiation Hs biological process
branching involved in ureteric bud morphogenesis Hs biological process
cell fate specification Hs biological process
neural crest cell migration Hs biological process
morphogenesis of a branching structure Hs biological process
kidney development Hs biological process
vasculature development Hs biological process
heart looping Hs biological process
positive regulation of neuroblast proliferation Hs biological process
osteoblast development Hs biological process
lymphoid progenitor cell differentiation Hs biological process
determination of left/right asymmetry in lateral mesoderm Hs biological process
epithelial cell morphogenesis Hs biological process
retinal pigment epithelium development Hs biological process
patched binding Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
glycosaminoglycan binding Hs molecular function
extracellular region Hs cellular component
proteinaceous extracellular matrix Hs cellular component
extracellular space Hs cellular component
endoplasmic reticulum lumen Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
proteoglycan metabolic process Hs biological process
regulation of transcription, DNA-templated Hs biological process
proteolysis Hs biological process
endocytosis Hs biological process
smoothened signaling pathway Hs biological process
positive regulation of hh target transcription factor activity Hs biological process
cell-cell signaling Hs biological process
multicellular organism development Hs biological process
spermatid development Hs biological process
determination of left/right symmetry Hs biological process
pattern specification process Hs biological process
ectoderm development Hs biological process
neuroblast proliferation Hs biological process
axon guidance Hs biological process
central nervous system development Hs biological process
ventral midline development Hs biological process
hindgut morphogenesis Hs biological process
heart development Hs biological process
blood coagulation Hs biological process
androgen metabolic process Hs biological process
peptidase activity Hs molecular function
zinc ion binding Hs molecular function
cell proliferation Hs biological process
positive regulation of cell proliferation Hs biological process
response to mechanical stimulus Hs biological process
embryonic pattern specification Hs biological process
polarity specification of anterior/posterior axis Hs biological process
anterior/posterior pattern specification Hs biological process
dorsal/ventral pattern formation Hs biological process
cell surface Hs cellular component
regulation of gene expression Hs biological process
regulation of receptor activity Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
oligodendrocyte development Hs biological process
striated muscle tissue development Hs biological process
morphogen activity Hs molecular function
membrane Hs cellular component
intein-mediated protein splicing Hs biological process
hydrolase activity Hs molecular function
spinal cord dorsal/ventral patterning Hs biological process
spinal cord motor neuron differentiation Hs biological process
thalamus development Hs biological process
forebrain regionalization Hs biological process
establishment of cell polarity Hs biological process
cell differentiation Hs biological process
regulation of proteolysis Hs biological process
positive regulation of Wnt signaling pathway Hs biological process
negative regulation of Wnt signaling pathway Hs biological process
male sex determination Hs biological process
lung development Hs biological process
embryonic limb morphogenesis Hs biological process
negative regulation of cell migration Hs biological process
male genitalia development Hs biological process
thyroid gland development Hs biological process
forebrain development Hs biological process
midbrain development Hs biological process
hindbrain development Hs biological process
pancreas development Hs biological process
response to estradiol Hs biological process
negative regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
T cell differentiation in thymus Hs biological process
negative regulation of transcription elongation from RNA polymerase II promoter Hs biological process
protein localization to nucleus Hs biological process
embryonic hindlimb morphogenesis Hs biological process
multicellular organism growth Hs biological process
chondrocyte proliferation Hs biological process
regulation of growth Hs biological process
regulation of cell proliferation Hs biological process
negative regulation of protein catabolic process Hs biological process
positive regulation of protein import into nucleus Hs biological process
odontogenesis Hs biological process
myelination Hs biological process
camera-type eye development Hs biological process
negative regulation of apoptotic process Hs biological process
laminin-1 binding Hs molecular function
skin development Hs biological process
response to estrogen Hs biological process
intermediate filament organization Hs biological process
membrane raft Hs cellular component
cell fate commitment Hs biological process
myoblast differentiation Hs biological process
bone resorption Hs biological process
negative regulation of cell differentiation Hs biological process
positive regulation of cell differentiation Hs biological process
positive regulation of smoothened signaling pathway Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
cell development Hs biological process
thymus development Hs biological process
digestive tract morphogenesis Hs biological process
embryonic digestive tract morphogenesis Hs biological process
embryonic organ development Hs biological process
developmental growth Hs biological process
embryonic camera-type eye morphogenesis Hs biological process
embryonic morphogenesis Hs biological process
embryonic foregut morphogenesis Hs biological process
anatomical structure formation involved in morphogenesis Hs biological process
neuron fate commitment Hs biological process
neuron development Hs biological process
embryonic skeletal system development Hs biological process
oligodendrocyte differentiation Hs biological process
positive regulation of oligodendrocyte differentiation Hs biological process
smooth muscle tissue development Hs biological process
branching morphogenesis of an epithelial tube Hs biological process
inner ear development Hs biological process
anatomical structure development Hs biological process
formation of anatomical boundary Hs biological process
stem cell development Hs biological process
positive regulation of epithelial cell proliferation Hs biological process
striated muscle cell differentiation Hs biological process
positive regulation of striated muscle cell differentiation Hs biological process
cartilage development Hs biological process
positive regulation of cell division Hs biological process
palate development Hs biological process
canonical Wnt signaling pathway Hs biological process
limb development Hs biological process
limb bud formation Hs biological process
head morphogenesis Hs biological process
trachea development Hs biological process
trachea morphogenesis Hs biological process
salivary gland cavitation Hs biological process
artery development Hs biological process
somite development Hs biological process
dopaminergic neuron differentiation Hs biological process
renal system development Hs biological process
embryonic skeletal joint development Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
epithelial cell-cell adhesion Hs biological process
apoptotic signaling pathway Hs biological process
regulation of protein localization to nucleus Hs biological process

GO (Blast)

19 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
patched binding Hs molecular function 289 8.23e-92
calcium ion binding Hs molecular function 289 8.23e-92
protein binding Hs molecular function 289 8.23e-92
glycosaminoglycan binding Hs molecular function 276 4.64e-86
extracellular region Hs cellular component 289 8.23e-92
proteinaceous extracellular matrix Hs cellular component 280 6.29e-88
extracellular space Hs cellular component 289 8.23e-92
endoplasmic reticulum lumen Hs cellular component 276 4.64e-86
cytosol Hs cellular component 276 4.64e-86
plasma membrane Hs cellular component 289 8.23e-92
peptidase activity Hs molecular function 289 8.23e-92
zinc ion binding Hs molecular function 289 8.23e-92
cell surface Hs cellular component 276 4.64e-86
morphogen activity Hs molecular function 276 4.64e-86
membrane Hs cellular component 289 8.23e-92
hydrolase activity Hs molecular function 289 8.23e-92
laminin-1 binding Hs molecular function 276 4.64e-86
membrane raft Hs cellular component 276 4.64e-86
metal ion binding Hs molecular function 289 8.23e-92

GO (InterProScan)

5 results

GO Term Analysis Type e-value
proteolysis Pfam biological process 4.1E-46
cell-cell signaling Pfam biological process 3.1E-72
multicellular organism development PRINTS biological process 2.8E-51
peptidase activity Pfam molecular function 4.1E-46
intein-mediated protein splicing ProSiteProfiles biological process 8.941

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