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Gene Card

Best human hits

IKBKB; IKBKE; TBK1

Species

B.schlosseri

Unique Gene ID

Boschl.g00003893

Gene Model ID

Boschl.CG.Botznik2013.chrUn.g03893

Location

chrUn:25204368..25213041

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chrUn.g03893.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

54 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
activation of innate immune response Hs biological process
immune system process Hs biological process
nucleic acid binding Hs molecular function
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
NF-kappaB-inducing kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
protein phosphorylation Hs biological process
inflammatory response Hs biological process
immune response Hs biological process
cellular response to DNA damage stimulus Hs biological process
I-kappaB kinase/NF-kappaB signaling Hs biological process
I-kappaB phosphorylation Hs biological process
IkappaB kinase activity Hs molecular function
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
response to virus Hs biological process
endosome membrane Hs cellular component
negative regulation of gene expression Hs biological process
positive regulation of lipid storage Hs biological process
viral process Hs biological process
aggresome Hs cellular component
positive regulation of macroautophagy Hs biological process
kinase activity Hs molecular function
phosphorylation Hs biological process
PML body Hs cellular component
transferase activity Hs molecular function
peptidyl-serine phosphorylation Hs biological process
peptidyl-threonine phosphorylation Hs biological process
ubiquitin protein ligase binding Hs molecular function
mitochondrial membrane Hs cellular component
negative regulation of type I interferon production Hs biological process
positive regulation of type I interferon production Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
TRIF-dependent toll-like receptor signaling pathway Hs biological process
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function
NIK/NF-kappaB signaling Hs biological process
identical protein binding Hs molecular function
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
innate immune response Hs biological process
positive regulation of interferon-beta biosynthetic process Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
defense response to Gram-positive bacterium Hs biological process
phosphoprotein binding Hs molecular function
protein homooligomerization Hs biological process
defense response to virus Hs biological process
cellular response to virus Hs biological process
regulation of neuron death Hs biological process
positive regulation of xenophagy Hs biological process

GO (Blast)

31 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 394 2.94e-128
nucleic acid binding Hs molecular function 394 2.94e-128
protein kinase activity Hs molecular function 394 2.94e-128
protein serine/threonine kinase activity Hs molecular function 394 2.94e-128
NF-kappaB-inducing kinase activity Hs molecular function 351 5.57e-112
protein binding Hs molecular function 394 2.94e-128
ATP binding Hs molecular function 394 2.94e-128
nucleus Hs cellular component 351 5.57e-112
nucleoplasm Hs cellular component 394 2.94e-128
cytoplasm Hs cellular component 394 2.94e-128
cytosol Hs cellular component 394 2.94e-128
IkappaB kinase activity Hs molecular function 351 5.57e-112
IkappaB kinase complex Hs cellular component 84.3 8.48e-17
cytoplasmic side of plasma membrane Hs cellular component 84.3 8.48e-17
endosome membrane Hs cellular component 394 2.94e-128
membrane Hs cellular component 84.3 8.48e-17
aggresome Hs cellular component 394 2.94e-128
kinase activity Hs molecular function 394 2.94e-128
PML body Hs cellular component 351 5.57e-112
transferase activity Hs molecular function 394 2.94e-128
protein kinase binding Hs molecular function 84.3 8.48e-17
ubiquitin protein ligase binding Hs molecular function 351 5.57e-112
mitochondrial membrane Hs cellular component 351 5.57e-112
CD40 receptor complex Hs cellular component 84.3 8.48e-17
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function 351 5.57e-112
identical protein binding Hs molecular function 394 2.94e-128
protein homodimerization activity Hs molecular function 84.3 8.48e-17
membrane raft Hs cellular component 84.3 8.48e-17
protein heterodimerization activity Hs molecular function 84.3 8.48e-17
phosphoprotein binding Hs molecular function 394 2.94e-128
scaffold protein binding Hs molecular function 84.3 8.48e-17

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 3.3E-21
ATP binding Pfam molecular function 3.3E-21
protein phosphorylation Pfam biological process 3.3E-21

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