Aniseed - Gene card

Gene Card

Best human hits

EZH1; EZH2; SETD2

Species

B.schlosseri

Unique Gene ID

Boschl.g00013519

Gene Model ID

Boschl.CG.Botznik2013.chrUn.g13519

Location

chrUn:87223996..87226228

Transcript Models and Sequences

Boschl.CG.Botznik2013.chrUn.g13519.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

9 results

IPR Term	Analysis	Definition
SET_dom	Pfam	SET domain
EZH1	PANTHER	Histone-lysine N-methyltransferase EZH1
SET_dom	SMART	SET domain
Homeobox-like_sf	SUPERFAMILY	Homeobox-like domain superfamily
SET_dom	ProSiteProfiles	SET domain
SANT/Myb	CDD	SANT/Myb domain
CXC_dom	ProSiteProfiles	CXC domain
Tesmin/TSO1-like_CXC	SMART	Tesmin/TSO1-like CXC domain
SANT/Myb	SMART	SANT/Myb domain

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

64 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
nuclear chromatin	Hs	cellular component
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II core promoter sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
core promoter binding	Hs	molecular function
regulation of protein phosphorylation	Hs	biological process
DNA binding	Hs	molecular function
chromatin binding	Hs	molecular function
RNA binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
DNA methylation	Hs	biological process
chromatin organization	Hs	biological process
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
methyltransferase activity	Hs	molecular function
anatomical structure morphogenesis	Hs	biological process
regulation of gene expression	Hs	biological process
negative regulation of gene expression	Hs	biological process
positive regulation of epithelial to mesenchymal transition	Hs	biological process
regulation of gliogenesis	Hs	biological process
protein-lysine N-methyltransferase activity	Hs	molecular function
histone methylation	Hs	biological process
transferase activity	Hs	molecular function
histone-lysine N-methyltransferase activity	Hs	molecular function
cerebellar cortex development	Hs	biological process
chromatin DNA binding	Hs	molecular function
methylation	Hs	biological process
response to estradiol	Hs	biological process
negative regulation of transcription elongation from RNA polymerase II promoter	Hs	biological process
histone lysine methylation	Hs	biological process
ESC/E(Z) complex	Hs	cellular component
histone methyltransferase activity	Hs	molecular function
regulation of cell proliferation	Hs	biological process
regulation of circadian rhythm	Hs	biological process
ribonucleoprotein complex binding	Hs	molecular function
positive regulation of MAP kinase activity	Hs	biological process
negative regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
positive regulation of GTPase activity	Hs	biological process
sequence-specific DNA binding	Hs	molecular function
transcription regulatory region DNA binding	Hs	molecular function
pronucleus	Hs	cellular component
negative regulation of epidermal cell differentiation	Hs	biological process
negative regulation of gene expression, epigenetic	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
histone methyltransferase activity (H3-K27 specific)	Hs	molecular function
negative regulation of retinoic acid receptor signaling pathway	Hs	biological process
rhythmic process	Hs	biological process
regulation of neurogenesis	Hs	biological process
cellular response to hydrogen peroxide	Hs	biological process
G1 to G0 transition	Hs	biological process
histone H3-K27 methylation	Hs	biological process
primary miRNA binding	Hs	molecular function
protein localization to chromatin	Hs	biological process
positive regulation of protein serine/threonine kinase activity	Hs	biological process
histone H3-K27 trimethylation	Hs	biological process
positive regulation of dendrite development	Hs	biological process
promoter-specific chromatin binding	Hs	molecular function
negative regulation of G1/S transition of mitotic cell cycle	Hs	biological process

GO (Blast)

30 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nuclear chromatin	Hs	cellular component	809	0.0
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	809	0.0
RNA polymerase II core promoter sequence-specific DNA binding	Hs	molecular function	809	0.0
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	809	0.0
core promoter binding	Hs	molecular function	809	0.0
DNA binding	Hs	molecular function	809	0.0
chromatin binding	Hs	molecular function	809	0.0
RNA binding	Hs	molecular function	809	0.0
protein binding	Hs	molecular function	809	0.0
nucleus	Hs	cellular component	809	0.0
nucleoplasm	Hs	cellular component	809	0.0
chromosome	Hs	cellular component	102	4.21e-22
cytoplasm	Hs	cellular component	809	0.0
methyltransferase activity	Hs	molecular function	809	0.0
protein-lysine N-methyltransferase activity	Hs	molecular function	809	0.0
transferase activity	Hs	molecular function	809	0.0
histone-lysine N-methyltransferase activity	Hs	molecular function	809	0.0
chromatin DNA binding	Hs	molecular function	809	0.0
ESC/E(Z) complex	Hs	cellular component	809	0.0
histone methyltransferase activity	Hs	molecular function	809	0.0
alpha-tubulin binding	Hs	molecular function	102	4.21e-22
ribonucleoprotein complex binding	Hs	molecular function	809	0.0
sequence-specific DNA binding	Hs	molecular function	809	0.0
transcription regulatory region DNA binding	Hs	molecular function	809	0.0
pronucleus	Hs	cellular component	809	0.0
metal ion binding	Hs	molecular function	102	4.21e-22
histone methyltransferase activity (H3-K36 specific)	Hs	molecular function	102	4.21e-22
histone methyltransferase activity (H3-K27 specific)	Hs	molecular function	809	0.0
primary miRNA binding	Hs	molecular function	809	0.0
promoter-specific chromatin binding	Hs	molecular function	809	0.0

GO (InterProScan)

4 results

GO Term	Analysis	Type	e-value
DNA binding	SUPERFAMILY	molecular function	9.09E-6
protein binding	SMART	molecular function	5.0E-32
histone-lysine N-methyltransferase activity	PANTHER	molecular function	4.4E-279
histone H3-K27 methylation	PANTHER	biological process	4.4E-279