Gene Card
Best human hits
ILKAP; PPM1L; TAB1
Species
Unique Gene ID
Boschl.g00035251
Gene Model ID
Boschl.CG.Botznik2013.chrUn.g35251
Location
chrUn:230402335..230414548
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
7 results
| IPR Term | Analysis | Definition |
|---|---|---|
| PP2C | PANTHER | Protein phosphatase 2C family |
| PPM-type_phosphatase_dom | CDD | PPM-type phosphatase domain |
| PPM-type_phosphatase_dom | ProSiteProfiles | PPM-type phosphatase domain |
| PPM-type_phosphatase_dom | SMART | PPM-type phosphatase domain |
| PPM-type_dom_sf | SUPERFAMILY | PPM-type phosphatase domain superfamily |
| PPM-type_phosphatase_dom | Pfam | PPM-type phosphatase domain |
| PPM-type_dom_sf | Gene3D | PPM-type phosphatase domain superfamily |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
27 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| activation of MAPKKK activity | Hs | biological process |
| activation of MAPK activity | Hs | biological process |
| MyD88-dependent toll-like receptor signaling pathway | Hs | biological process |
| heart morphogenesis | Hs | biological process |
| catalytic activity | Hs | molecular function |
| protein serine/threonine phosphatase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| cytosol | Hs | cellular component |
| protein dephosphorylation | Hs | biological process |
| transforming growth factor beta receptor signaling pathway | Hs | biological process |
| I-kappaB kinase/NF-kappaB signaling | Hs | biological process |
| JNK cascade | Hs | biological process |
| enzyme activator activity | Hs | molecular function |
| endosome membrane | Hs | cellular component |
| kinase activity | Hs | molecular function |
| phosphorylation | Hs | biological process |
| protein deubiquitination | Hs | biological process |
| nuclear speck | Hs | cellular component |
| kinase activator activity | Hs | molecular function |
| lung development | Hs | biological process |
| aorta development | Hs | biological process |
| Fc-epsilon receptor signaling pathway | Hs | biological process |
| positive regulation of MAP kinase activity | Hs | biological process |
| mitogen-activated protein kinase p38 binding | Hs | molecular function |
| positive regulation of NF-kappaB transcription factor activity | Hs | biological process |
| coronary vasculature development | Hs | biological process |
| interleukin-1-mediated signaling pathway | Hs | biological process |
GO (Blast)
21 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| catalytic activity | Hs | molecular function | 209 | 5.80e-64 |
| phosphoprotein phosphatase activity | Hs | molecular function | 62.4 | 5.13e-11 |
| protein serine/threonine phosphatase activity | Hs | molecular function | 209 | 5.80e-64 |
| protein binding | Hs | molecular function | 209 | 5.80e-64 |
| nucleus | Hs | cellular component | 62.4 | 5.13e-11 |
| nucleoplasm | Hs | cellular component | 62.4 | 5.13e-11 |
| cytoplasm | Hs | cellular component | 62.4 | 5.13e-11 |
| endoplasmic reticulum membrane | Hs | cellular component | 55.1 | 1.41e-08 |
| cytosol | Hs | cellular component | 209 | 5.80e-64 |
| enzyme activator activity | Hs | molecular function | 209 | 5.80e-64 |
| endosome membrane | Hs | cellular component | 209 | 5.80e-64 |
| membrane | Hs | cellular component | 55.1 | 1.41e-08 |
| integral component of membrane | Hs | cellular component | 55.1 | 1.41e-08 |
| kinase activity | Hs | molecular function | 209 | 5.80e-64 |
| nuclear speck | Hs | cellular component | 209 | 5.80e-64 |
| hydrolase activity | Hs | molecular function | 62.4 | 5.13e-11 |
| kinase activator activity | Hs | molecular function | 209 | 5.80e-64 |
| cation binding | Hs | molecular function | 62.4 | 5.13e-11 |
| metal ion binding | Hs | molecular function | 62.4 | 5.13e-11 |
| mitogen-activated protein kinase p38 binding | Hs | molecular function | 209 | 5.80e-64 |
| extracellular exosome | Hs | cellular component | 55.1 | 1.41e-08 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| catalytic activity | CDD | molecular function | 2.62554E-29 |
| protein serine/threonine phosphatase activity | PANTHER | molecular function | 3.4E-70 |
| protein dephosphorylation | PANTHER | biological process | 3.4E-70 |
