Gene Card
Best human hits
DAB2IP; RASA1; RASAL2
Species
Unique Gene ID
Boschl.g00043400
Gene Model ID
Boschl.CG.Botznik2013.chrUn.g43400
Location
chrUn:281122443..281133461
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
21 results
| IPR Term | Analysis | Definition |
|---|---|---|
| SH2 | PRINTS | SH2 domain |
| SH3_domain | SMART | SH3 domain |
| SH3_domain | ProSiteProfiles | SH3 domain |
| SH2 | ProSiteProfiles | SH2 domain |
| RasGAP_SH3 | CDD | RasGAP, SH3 domain |
| p120-RasGAP | PANTHER | Ras GTPase-activating protein 1 |
| PH_domain | SMART | Pleckstrin homology domain |
| PH-like_dom_sf | Gene3D | PH-like domain superfamily |
| PH_domain | Pfam | Pleckstrin homology domain |
| SH2_dom_sf | Gene3D | SH2 domain superfamily |
| SH2_dom_sf | SUPERFAMILY | SH2 domain superfamily |
| C2_dom | SMART | C2 domain |
| RasGAP_dom | ProSiteProfiles | Ras GTPase-activating domain |
| PH_domain | ProSiteProfiles | Pleckstrin homology domain |
| SH2 | Pfam | SH2 domain |
| C2_domain_sf | Gene3D | C2 domain superfamily |
| SH3_domain | Pfam | SH3 domain |
| SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
| SH2 | SMART | SH2 domain |
| C2_dom | Pfam | C2 domain |
| Rho_GTPase_activation_prot | SUPERFAMILY | Rho GTPase activation protein |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
42 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| ruffle | Hs | cellular component | 628 | 0.0 |
| phosphotyrosine residue binding | Hs | molecular function | 628 | 0.0 |
| GTPase activity | Hs | molecular function | 628 | 0.0 |
| GTPase activator activity | Hs | molecular function | 628 | 0.0 |
| receptor binding | Hs | molecular function | 628 | 0.0 |
| death receptor binding | Hs | molecular function | 97.1 | 1.63e-20 |
| protein binding | Hs | molecular function | 628 | 0.0 |
| cytoplasm | Hs | cellular component | 628 | 0.0 |
| cytosol | Hs | cellular component | 628 | 0.0 |
| plasma membrane | Hs | cellular component | 628 | 0.0 |
| membrane | Hs | cellular component | 97.1 | 1.63e-20 |
| SH3 domain binding | Hs | molecular function | 97.1 | 1.63e-20 |
| potassium channel inhibitor activity | Hs | molecular function | 628 | 0.0 |
| kinase binding | Hs | molecular function | 97.1 | 1.63e-20 |
| protein kinase binding | Hs | molecular function | 97.1 | 1.63e-20 |
| endocytic vesicle | Hs | cellular component | 97.1 | 1.63e-20 |
| axon | Hs | cellular component | 97.1 | 1.63e-20 |
| dendrite | Hs | cellular component | 97.1 | 1.63e-20 |
| intrinsic component of the cytoplasmic side of the plasma membrane | Hs | cellular component | 628 | 0.0 |
| mitogen-activated protein kinase kinase binding | Hs | molecular function | 97.1 | 1.63e-20 |
| mitogen-activated protein kinase kinase kinase binding | Hs | molecular function | 97.1 | 1.63e-20 |
| phosphatidylinositol-3-phosphate binding | Hs | molecular function | 97.1 | 1.63e-20 |
| neuronal cell body membrane | Hs | cellular component | 97.1 | 1.63e-20 |
| signaling adaptor activity | Hs | molecular function | 97.1 | 1.63e-20 |
| phosphatidylinositol 3-kinase regulatory subunit binding | Hs | molecular function | 97.1 | 1.63e-20 |
| identical protein binding | Hs | molecular function | 97.1 | 1.63e-20 |
| protein homodimerization activity | Hs | molecular function | 97.1 | 1.63e-20 |
| cell projection | Hs | cellular component | 97.1 | 1.63e-20 |
| neuronal cell body | Hs | cellular component | 97.1 | 1.63e-20 |
| vascular endothelial growth factor receptor 2 binding | Hs | molecular function | 97.1 | 1.63e-20 |
| phosphatidylinositol 3-kinase binding | Hs | molecular function | 97.1 | 1.63e-20 |
| cerebellar mossy fiber | Hs | cellular component | 97.1 | 1.63e-20 |
| climbing fiber | Hs | cellular component | 97.1 | 1.63e-20 |
| macromolecular complex binding | Hs | molecular function | 97.1 | 1.63e-20 |
| cadherin binding | Hs | molecular function | 97.1 | 1.63e-20 |
| GTPase binding | Hs | molecular function | 628 | 0.0 |
| protein phosphatase 2A binding | Hs | molecular function | 97.1 | 1.63e-20 |
| extracellular exosome | Hs | cellular component | 97.1 | 1.63e-20 |
| phosphatidylinositol-4-phosphate binding | Hs | molecular function | 97.1 | 1.63e-20 |
| 14-3-3 protein binding | Hs | molecular function | 97.1 | 1.63e-20 |
| parallel fiber | Hs | cellular component | 97.1 | 1.63e-20 |
| AIP1-IRE1 complex | Hs | cellular component | 97.1 | 1.63e-20 |
GO (InterProScan)
6 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| GTPase activator activity | PANTHER | molecular function | 1.8E-250 |
| protein binding | SUPERFAMILY | molecular function | 1.11E-8 |
| signal transduction | SUPERFAMILY | biological process | 5.89E-17 |
| regulation of GTPase activity | ProSiteProfiles | biological process | 17.132 |
| positive regulation of GTPase activity | PANTHER | biological process | 1.8E-250 |
| negative regulation of Ras protein signal transduction | PANTHER | biological process | 1.8E-250 |
