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Gene Card

Best human hits

MITF; TFE3; TFEB

Species

C.savignyi

Unique Gene ID

Cisavi.g00000204

Gene Model ID

Cisavi.CG.ENS81.R0.3134182-3143755

Location

R0:3134181..3143755

Transcript Models and Sequences

  Cisavi.CG.ENS81.R0.3134182-3143755.17964.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
TFEB PANTHER Transcription factor EB
bHLH_dom Pfam Myc-type, basic helix-loop-helix (bHLH) domain
HLH_DNA-bd_sf SUPERFAMILY Helix-loop-helix DNA-binding domain superfamily
HLH_DNA-bd_sf Gene3D Helix-loop-helix DNA-binding domain superfamily
bHLH_dom SMART Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom CDD Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom ProSiteProfiles Myc-type, basic helix-loop-helix (bHLH) domain
MiT/TFE_N Pfam MiT/TFE transcription factors, N-terminal

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

51 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
adaptive immune response Hs biological process
immune system process Hs biological process
DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
autophagy Hs biological process
humoral immune response Hs biological process
lysosome organization Hs biological process
multicellular organism development Hs biological process
regulation of gene expression Hs biological process
positive regulation of autophagy Hs biological process
positive regulation of gene expression Hs biological process
Wnt signaling pathway Hs biological process
protein sumoylation Hs biological process
cell differentiation Hs biological process
osteoclast differentiation Hs biological process
melanocyte differentiation Hs biological process
macromolecular complex Hs cellular component
regulation of cell proliferation Hs biological process
camera-type eye development Hs biological process
negative regulation of apoptotic process Hs biological process
pigmentation Hs biological process
transcription regulatory region DNA binding Hs molecular function
cell fate commitment Hs biological process
regulation of osteoclast differentiation Hs biological process
positive regulation of cell adhesion Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
bone remodeling Hs biological process
protein dimerization activity Hs molecular function
E-box binding Hs molecular function
regulation of RNA biosynthetic process Hs biological process
transcription coactivator activity Hs molecular function
transcription corepressor activity Hs molecular function
cellular response to heat Hs biological process
negative regulation of nucleic acid-templated transcription Hs biological process

GO (Blast)

17 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 215 1.62e-65
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 215 1.62e-65
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 215 1.62e-65
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 193 2.14e-57
DNA binding Hs molecular function 215 1.62e-65
chromatin binding Hs molecular function 193 2.14e-57
transcription factor activity, sequence-specific DNA binding Hs molecular function 215 1.62e-65
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 193 2.14e-57
protein binding Hs molecular function 215 1.62e-65
nucleus Hs cellular component 215 1.62e-65
nucleoplasm Hs cellular component 215 1.62e-65
cytoplasm Hs cellular component 190 3.66e-56
cytosol Hs cellular component 215 1.62e-65
macromolecular complex Hs cellular component 193 2.14e-57
transcription regulatory region DNA binding Hs molecular function 215 1.62e-65
protein dimerization activity Hs molecular function 215 1.62e-65
E-box binding Hs molecular function 193 2.14e-57

GO (InterProScan)

3 results

GO Term Analysis Type e-value
humoral immune response PANTHER biological process 5.3E-95
positive regulation of transcription, DNA-templated PANTHER biological process 5.3E-95
protein dimerization activity PANTHER molecular function 5.3E-95





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