Gene Card
Best human hits
LRP4; LRP6
Species
Unique Gene ID
Cisavi.g00002490
Gene Model ID
Cisavi.CG.ENS81.R15.1264403-1281617
Location
R15:1264402..1281617
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
20 results
| IPR Term | Analysis | Definition |
|---|---|---|
| LDL_receptor-like_sf | SUPERFAMILY | LDL receptor-like superfamily |
| LDrepeatLR_classA_rpt | PRINTS | Low-density lipoprotein (LDL) receptor class A repeat |
| EGF-like_Ca-bd_dom | SMART | EGF-like calcium-binding domain |
| LDrepeatLR_classA_rpt | CDD | Low-density lipoprotein (LDL) receptor class A repeat |
| LRP4 | PANTHER | Low-density lipoprotein receptor-related protein 4 |
| LDrepeatLR_classA_rpt | Pfam | Low-density lipoprotein (LDL) receptor class A repeat |
| LDLR_classB_rpt | ProSiteProfiles | LDLR class B repeat |
| 6-blade_b-propeller_TolB-like | Gene3D | Six-bladed beta-propeller, TolB-like |
| LDrepeatLR_classA_rpt | ProSiteProfiles | Low-density lipoprotein (LDL) receptor class A repeat |
| EGF-like_CS | ProSitePatterns | EGF-like, conserved site |
| LDLR_classB_rpt | SMART | LDLR class B repeat |
| LDrepeatLR_classA_rpt | SMART | Low-density lipoprotein (LDL) receptor class A repeat |
| LDLR_classB_rpt | Pfam | LDLR class B repeat |
| LDLR_class-A_CS | ProSitePatterns | Low-density lipoprotein (LDL) receptor class A, conserved site |
| EGF-like_dom | SMART | EGF-like domain |
| EGF-like_Ca-bd_dom | Pfam | EGF-like calcium-binding domain |
| EGF-type_Asp/Asn_hydroxyl_site | ProSitePatterns | EGF-type aspartate/asparagine hydroxylation site |
| EGF-like_dom | ProSiteProfiles | EGF-like domain |
| Growth_fac_rcpt_cys_sf | SUPERFAMILY | Growth factor receptor cysteine-rich domain superfamily |
| EGF_Ca-bd_CS | ProSitePatterns | EGF-like calcium-binding, conserved site |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
49 results
GO (Blast)
38 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| low-density lipoprotein receptor activity | Hs | molecular function | 824 | 0.0 |
| receptor binding | Hs | molecular function | 824 | 0.0 |
| frizzled binding | Hs | molecular function | 824 | 0.0 |
| calcium ion binding | Hs | molecular function | 1280 | 0.0 |
| protein binding | Hs | molecular function | 1280 | 0.0 |
| extracellular region | Hs | cellular component | 824 | 0.0 |
| early endosome | Hs | cellular component | 824 | 0.0 |
| endoplasmic reticulum | Hs | cellular component | 824 | 0.0 |
| Golgi apparatus | Hs | cellular component | 824 | 0.0 |
| plasma membrane | Hs | cellular component | 1280 | 0.0 |
| caveola | Hs | cellular component | 824 | 0.0 |
| cell surface | Hs | cellular component | 1280 | 0.0 |
| postsynaptic density | Hs | cellular component | 1280 | 0.0 |
| membrane | Hs | cellular component | 1280 | 0.0 |
| integral component of membrane | Hs | cellular component | 1280 | 0.0 |
| flotillin complex | Hs | cellular component | 1280 | 0.0 |
| Wnt-protein binding | Hs | molecular function | 1280 | 0.0 |
| kinase inhibitor activity | Hs | molecular function | 824 | 0.0 |
| toxin transporter activity | Hs | molecular function | 824 | 0.0 |
| dendrite | Hs | cellular component | 1280 | 0.0 |
| receptor tyrosine kinase binding | Hs | molecular function | 1280 | 0.0 |
| cytoplasmic vesicle | Hs | cellular component | 824 | 0.0 |
| neuromuscular junction | Hs | cellular component | 1280 | 0.0 |
| early endosome membrane | Hs | cellular component | 824 | 0.0 |
| apolipoprotein binding | Hs | molecular function | 1280 | 0.0 |
| identical protein binding | Hs | molecular function | 824 | 0.0 |
| protein homodimerization activity | Hs | molecular function | 1280 | 0.0 |
| Wnt-activated receptor activity | Hs | molecular function | 1280 | 0.0 |
| neuronal cell body | Hs | cellular component | 1280 | 0.0 |
| receptor complex | Hs | cellular component | 1280 | 0.0 |
| membrane raft | Hs | cellular component | 824 | 0.0 |
| synapse | Hs | cellular component | 824 | 0.0 |
| coreceptor activity involved in Wnt signaling pathway | Hs | molecular function | 824 | 0.0 |
| synaptic membrane | Hs | cellular component | 1280 | 0.0 |
| scaffold protein binding | Hs | molecular function | 1280 | 0.0 |
| coreceptor activity involved in canonical Wnt signaling pathway | Hs | molecular function | 824 | 0.0 |
| Wnt-Frizzled-LRP5/6 complex | Hs | cellular component | 824 | 0.0 |
| Wnt signalosome | Hs | cellular component | 824 | 0.0 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| calcium ion binding | SMART | molecular function | 5.8E-10 |
| protein binding | PRINTS | molecular function | 3.4E-52 |
| BMP signaling pathway | PANTHER | biological process | 2.5E-258 |
| animal organ development | PANTHER | biological process | 2.5E-258 |
| regulation of canonical Wnt signaling pathway | PANTHER | biological process | 2.5E-258 |
