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GENE CARD

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Gene Card

Best human hits

SCN1A; SCN2A; SCN9A

Species

C.savignyi

Unique Gene ID

Cisavi.g00002706

Gene Model ID

Cisavi.CG.ENS81.R156.1029810-1050356

Location

R156:1029809..1050356

Transcript Models and Sequences

  Cisavi.CG.ENS81.R156.1029810-1050356.16597.t
Cisavi.CG.ENS81.R156.1029810-1050356.16598.t
Cisavi.CG.ENS81.R156.1029810-1050356.16599.t
Cisavi.CG.ENS81.R156.1029810-1050356.16600.t
Cisavi.CG.ENS81.R156.1029810-1050356.16601.t
Cisavi.CG.ENS81.R156.1029810-1050356.16602.t
Cisavi.CG.ENS81.R156.1029810-1050356.16603.t
Cisavi.CG.ENS81.R156.1029810-1050356.16604.t
Cisavi.CG.ENS81.R156.1029810-1050356.16605.t
Cisavi.CG.ENS81.R156.1029810-1050356.16606.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
Volt_channel_dom_sf Gene3D Voltage-dependent channel domain superfamily
Na_channel_asu PRINTS Voltage gated sodium channel, alpha subunit
Ion_trans_dom Pfam Ion transport domain
Na_trans_assoc Pfam Sodium ion transport-associated
GPHH_dom Pfam Voltage-dependent L-type calcium channel, IQ-associated domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

97 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
action potential Hs biological process
voltage-gated sodium channel complex Hs cellular component
ion channel activity Hs molecular function
voltage-gated ion channel activity Hs molecular function
voltage-gated sodium channel activity Hs molecular function
sodium channel activity Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
nucleoplasm Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
ion transport Hs biological process
sodium ion transport Hs biological process
inflammatory response Hs biological process
nervous system development Hs biological process
adult walking behavior Hs biological process
intrinsic apoptotic signaling pathway in response to osmotic stress Hs biological process
response to toxic substance Hs biological process
post-embryonic development Hs biological process
intercalated disc Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
nuclear body Hs cellular component
neuronal action potential propagation Hs biological process
neuronal action potential Hs biological process
sensory perception of pain Hs biological process
Z disc Hs cellular component
T-tubule Hs cellular component
axon Hs cellular component
intrinsic component of plasma membrane Hs cellular component
sodium ion binding Hs molecular function
node of Ranvier Hs cellular component
paranode region of axon Hs cellular component
ion transmembrane transport Hs biological process
sodium channel complex Hs cellular component
regulation of ion transmembrane transport Hs biological process
sodium ion transmembrane transport Hs biological process
regulation of membrane potential Hs biological process
myelination Hs biological process
cell projection Hs cellular component
neuronal cell body Hs cellular component
axon initial segment Hs cellular component
behavioral response to pain Hs biological process
neuromuscular process controlling posture Hs biological process
detection of mechanical stimulus involved in sensory perception of pain Hs biological process
neuron apoptotic process Hs biological process
transmembrane transport Hs biological process
membrane depolarization during action potential Hs biological process
nucleotide binding Hs molecular function
regulation of heart rate Hs biological process
cardiac ventricle development Hs biological process
calmodulin binding Hs molecular function
ATP binding Hs molecular function
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
caveola Hs cellular component
muscle contraction Hs biological process
peripheral nervous system development Hs biological process
sensory perception Hs biological process
cell surface Hs cellular component
lateral plasma membrane Hs cellular component
fibroblast growth factor binding Hs molecular function
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
protein domain specific binding Hs molecular function
telencephalon development Hs biological process
cerebellum development Hs biological process
ankyrin binding Hs molecular function
cytoplasmic vesicle Hs cellular component
ubiquitin protein ligase binding Hs molecular function
sarcolemma Hs cellular component
response to drug Hs biological process
C-fiber Hs cellular component
ion channel binding Hs molecular function
positive regulation of action potential Hs biological process
perinuclear region of cytoplasm Hs cellular component
positive regulation of epithelial cell proliferation Hs biological process
nitric-oxide synthase binding Hs molecular function
membrane depolarization Hs biological process
regulation of sensory perception of pain Hs biological process
sodium ion homeostasis Hs biological process
regulation of cardiac muscle contraction Hs biological process
cardiac muscle contraction Hs biological process
regulation of ventricular cardiac muscle cell membrane repolarization Hs biological process
cardiac conduction Hs biological process
extracellular exosome Hs cellular component
cellular response to calcium ion Hs biological process
clathrin complex Hs cellular component
regulation of cardiac muscle cell contraction Hs biological process
voltage-gated sodium channel activity involved in cardiac muscle cell action potential Hs molecular function
voltage-gated sodium channel activity involved in AV node cell action potential Hs molecular function
voltage-gated sodium channel activity involved in bundle of His cell action potential Hs molecular function
voltage-gated sodium channel activity involved in Purkinje myocyte action potential Hs molecular function
voltage-gated sodium channel activity involved in SA node cell action potential Hs molecular function
regulation of heart rate by cardiac conduction Hs biological process
scaffold protein binding Hs molecular function
glial cell projection Hs cellular component

GO (Blast)

25 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
voltage-gated sodium channel complex Hs cellular component 1797 0.0
ion channel activity Hs molecular function 1797 0.0
voltage-gated ion channel activity Hs molecular function 1797 0.0
voltage-gated sodium channel activity Hs molecular function 1797 0.0
sodium channel activity Hs molecular function 1797 0.0
protein binding Hs molecular function 1797 0.0
intracellular Hs cellular component 1795 0.0
nucleoplasm Hs cellular component 1797 0.0
plasma membrane Hs cellular component 1797 0.0
integral component of plasma membrane Hs cellular component 1795 0.0
intercalated disc Hs cellular component 1797 0.0
membrane Hs cellular component 1797 0.0
integral component of membrane Hs cellular component 1797 0.0
nuclear body Hs cellular component 1797 0.0
Z disc Hs cellular component 1797 0.0
T-tubule Hs cellular component 1797 0.0
axon Hs cellular component 1797 0.0
intrinsic component of plasma membrane Hs cellular component 1795 0.0
sodium ion binding Hs molecular function 1793 0.0
node of Ranvier Hs cellular component 1797 0.0
paranode region of axon Hs cellular component 1795 0.0
sodium channel complex Hs cellular component 1797 0.0
cell projection Hs cellular component 1793 0.0
neuronal cell body Hs cellular component 1797 0.0
axon initial segment Hs cellular component 1797 0.0

GO (InterProScan)

7 results

GO Term Analysis Type e-value
voltage-gated sodium channel complex Pfam cellular component 4.2E-18
ion channel activity Pfam molecular function 2.9E-71
voltage-gated sodium channel activity Pfam molecular function 4.2E-18
ion transport Pfam biological process 2.9E-71
sodium ion transport Pfam biological process 4.2E-18
membrane Pfam cellular component 2.9E-71
transmembrane transport Pfam biological process 2.9E-71

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