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GENE CARD

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Gene Card

Best human hits

SFRP1; SFRP2; SFRP5

Species

C.savignyi

Unique Gene ID

Cisavi.g00003678

Gene Model ID

Cisavi.CG.ENS81.R19.2036110-2039743

Location

R19:2036109..2039743

Transcript Models and Sequences

  Cisavi.CG.ENS81.R19.2036110-2039743.15284.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
Frizzled_dom_sf SUPERFAMILY Frizzled cysteine-rich domain superfamily
Frizzled_dom ProSiteProfiles Frizzled domain
Frizzled_dom Pfam Frizzled domain
TIMP-like_OB-fold SUPERFAMILY Tissue inhibitor of metalloproteinases-like, OB-fold
Frizzled_dom_sf Gene3D Frizzled cysteine-rich domain superfamily
Netrin_domain ProSiteProfiles Netrin domain
Netrin_module_non-TIMP Pfam Netrin module, non-TIMP type
Frizzled_dom SMART Frizzled domain
Frizzled/SFRP PANTHER Frizzled/secreted frizzled-related protein
SFRP2 PANTHER Secreted frizzled-related protein 2

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

78 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
branching involved in blood vessel morphogenesis Hs biological process
somitogenesis Hs biological process
neural tube closure Hs biological process
fibronectin binding Hs molecular function
chondrocyte development Hs biological process
outflow tract morphogenesis Hs biological process
G-protein coupled receptor activity Hs molecular function
integrin binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
apoptotic process Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
cell-cell signaling Hs biological process
multicellular organism development Hs biological process
response to nutrient Hs biological process
enzyme activator activity Hs molecular function
positive regulation of cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
male gonad development Hs biological process
anterior/posterior pattern specification Hs biological process
regulation of receptor activity Hs biological process
negative regulation of gene expression Hs biological process
negative regulation of cardiac muscle cell apoptotic process Hs biological process
negative regulation of epithelial to mesenchymal transition Hs biological process
positive regulation of endopeptidase activity Hs biological process
regulation of neuron projection development Hs biological process
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
Wnt-protein binding Hs molecular function
neural tube development Hs biological process
regulation of Wnt signaling pathway Hs biological process
cell differentiation Hs biological process
negative regulation of Wnt signaling pathway Hs biological process
collagen fibril organization Hs biological process
positive regulation of cell growth Hs biological process
negative regulation of cell growth Hs biological process
negative regulation of cell migration Hs biological process
negative regulation of BMP signaling pathway Hs biological process
extracellular matrix Hs cellular component
cellular response to extracellular stimulus Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
positive regulation of cell adhesion mediated by integrin Hs biological process
non-canonical Wnt signaling pathway Hs biological process
post-anal tail morphogenesis Hs biological process
regulation of cell proliferation Hs biological process
response to drug Hs biological process
negative regulation of mesodermal cell fate specification Hs biological process
Wnt-activated receptor activity Hs molecular function
regulation of apoptotic process Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
negative regulation of JUN kinase activity Hs biological process
positive regulation of fat cell differentiation Hs biological process
positive regulation of osteoblast differentiation Hs biological process
positive regulation of angiogenesis Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
development of primary male sexual characteristics Hs biological process
receptor ligand activity Hs molecular function
digestive tract morphogenesis Hs biological process
negative regulation of epithelial cell proliferation Hs biological process
negative regulation of peptidyl-tyrosine phosphorylation Hs biological process
cartilage development Hs biological process
convergent extension involved in axis elongation Hs biological process
bone morphogenesis Hs biological process
sclerotome development Hs biological process
endopeptidase activator activity Hs molecular function
hematopoietic stem cell proliferation Hs biological process
cellular response to X-ray Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
regulation of establishment of planar polarity Hs biological process
planar cell polarity pathway involved in neural tube closure Hs biological process
Wnt signaling pathway involved in somitogenesis Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Hs biological process
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
regulation of stem cell division Hs biological process

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
fibronectin binding Hs molecular function 219 6.21e-70
cysteine-type endopeptidase activity Hs molecular function 154 1.73e-44
G-protein coupled receptor activity Hs molecular function 219 6.21e-70
frizzled binding Hs molecular function 154 1.73e-44
integrin binding Hs molecular function 219 6.21e-70
protein binding Hs molecular function 219 6.21e-70
extracellular region Hs cellular component 219 6.21e-70
proteinaceous extracellular matrix Hs cellular component 154 1.73e-44
extracellular space Hs cellular component 219 6.21e-70
intracellular Hs cellular component 154 1.73e-44
cytosol Hs cellular component 154 1.73e-44
plasma membrane Hs cellular component 154 1.73e-44
enzyme activator activity Hs molecular function 219 6.21e-70
drug binding Hs molecular function 154 1.73e-44
heparin binding Hs molecular function 154 1.73e-44
cell surface Hs cellular component 154 1.73e-44
integral component of membrane Hs cellular component 219 6.21e-70
Wnt-protein binding Hs molecular function 219 6.21e-70
extracellular matrix Hs cellular component 219 6.21e-70
identical protein binding Hs molecular function 154 1.73e-44
Wnt-activated receptor activity Hs molecular function 219 6.21e-70
receptor ligand activity Hs molecular function 219 6.21e-70
endopeptidase activator activity Hs molecular function 219 6.21e-70
extracellular exosome Hs cellular component 154 1.73e-44

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding SMART molecular function 4.4E-45