Aniseed - Gene card

Gene Card

Best human hits

NFE2; NFE2L1; NFE2L3

Species

C.savignyi

Unique Gene ID

Cisavi.g00004503

Gene Model ID

Cisavi.CG.ENS81.R215.169957-190543

Location

R215:169956..190543

Transcript Models and Sequences

Cisavi.CG.ENS81.R215.169957-190543.05164.t
Cisavi.CG.ENS81.R215.169957-190543.05165.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term	Analysis	Definition
bZIP	SMART	Basic-leucine zipper domain
bZIP_Maf	Pfam	Basic leucine zipper domain, Maf-type
bZIP	ProSitePatterns	Basic-leucine zipper domain
TF_DNA-bd_sf	SUPERFAMILY	Transcription factor, Skn-1-like, DNA-binding domain superfamily
bZIP	ProSiteProfiles	Basic-leucine zipper domain

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

84 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription regulatory region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II distal enhancer sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
core promoter proximal region sequence-specific DNA binding	Hs	molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II transcription factor binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	Hs	molecular function
DNA binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcription cofactor activity	Hs	molecular function
transcription coactivator activity	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
endoplasmic reticulum	Hs	cellular component
endoplasmic reticulum membrane	Hs	cellular component
cytosol	Hs	cellular component
nucleosome disassembly	Hs	biological process
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription from RNA polymerase II promoter	Hs	biological process
lipid metabolic process	Hs	biological process
heme biosynthetic process	Hs	biological process
inflammatory response	Hs	biological process
multicellular organism development	Hs	biological process
blood coagulation	Hs	biological process
hemostasis	Hs	biological process
blood circulation	Hs	biological process
steroid metabolic process	Hs	biological process
cholesterol metabolic process	Hs	biological process
lipid binding	Hs	molecular function
anatomical structure morphogenesis	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
PML body	Hs	cellular component
protein domain specific binding	Hs	molecular function
erythrocyte differentiation	Hs	biological process
macromolecular complex	Hs	cellular component
protein-DNA complex	Hs	cellular component
cellular response to oxidative stress	Hs	biological process
sequence-specific DNA binding	Hs	molecular function
macromolecular complex binding	Hs	molecular function
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
protein N-terminus binding	Hs	molecular function
WW domain binding	Hs	molecular function
chromatin	Hs	cellular component
RNA polymerase II activating transcription factor binding	Hs	molecular function
transcription cofactor binding	Hs	molecular function
Golgi apparatus	Hs	cellular component
centrosome	Hs	cellular component
plasma membrane	Hs	cellular component
aging	Hs	biological process
transcription factor binding	Hs	molecular function
proteasomal ubiquitin-independent protein catabolic process	Hs	biological process
positive regulation of gene expression	Hs	biological process
negative regulation of cardiac muscle cell apoptotic process	Hs	biological process
positive regulation of neuron projection development	Hs	biological process
protein ubiquitination	Hs	biological process
positive regulation of blood coagulation	Hs	biological process
endoplasmic reticulum unfolded protein response	Hs	biological process
response to endoplasmic reticulum stress	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter in response to stress	Hs	biological process
PERK-mediated unfolded protein response	Hs	biological process
cellular response to glucose starvation	Hs	biological process
proteasome-mediated ubiquitin-dependent protein catabolic process	Hs	biological process
transcription regulatory region DNA binding	Hs	molecular function
cell redox homeostasis	Hs	biological process
positive regulation of angiogenesis	Hs	biological process
regulation of embryonic development	Hs	biological process
positive regulation of glucose import	Hs	biological process
negative regulation of cell death	Hs	biological process
cellular response to hydrogen peroxide	Hs	biological process
cellular response to tumor necrosis factor	Hs	biological process
cellular response to hypoxia	Hs	biological process
cellular response to fluid shear stress	Hs	biological process
negative regulation of hematopoietic stem cell differentiation	Hs	biological process
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Hs	biological process
negative regulation of hydrogen peroxide-induced cell death	Hs	biological process
positive regulation of reactive oxygen species metabolic process	Hs	biological process

GO (Blast)

30 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
transcription regulatory region sequence-specific DNA binding	Hs	molecular function	159	3.42e-40
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	154	1.21e-38
RNA polymerase II distal enhancer sequence-specific DNA binding	Hs	molecular function	159	3.42e-40
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	159	3.42e-40
core promoter proximal region sequence-specific DNA binding	Hs	molecular function	144	3.15e-37
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	154	1.21e-38
transcriptional activator activity, RNA polymerase II transcription factor binding	Hs	molecular function	159	3.42e-40
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	Hs	molecular function	159	3.42e-40
DNA binding	Hs	molecular function	159	3.42e-40
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	159	3.42e-40
transcription cofactor activity	Hs	molecular function	159	3.42e-40
transcription coactivator activity	Hs	molecular function	154	1.21e-38
protein binding	Hs	molecular function	159	3.42e-40
nucleus	Hs	cellular component	159	3.42e-40
nucleoplasm	Hs	cellular component	144	3.15e-37
cytoplasm	Hs	cellular component	159	3.42e-40
endoplasmic reticulum	Hs	cellular component	159	3.42e-40
endoplasmic reticulum membrane	Hs	cellular component	159	3.42e-40
cytosol	Hs	cellular component	159	3.42e-40
lipid binding	Hs	molecular function	159	3.42e-40
membrane	Hs	cellular component	159	3.42e-40
integral component of membrane	Hs	cellular component	159	3.42e-40
PML body	Hs	cellular component	144	3.15e-37
protein domain specific binding	Hs	molecular function	159	3.42e-40
macromolecular complex	Hs	cellular component	159	3.42e-40
protein-DNA complex	Hs	cellular component	144	3.15e-37
sequence-specific DNA binding	Hs	molecular function	144	3.15e-37
macromolecular complex binding	Hs	molecular function	159	3.42e-40
protein N-terminus binding	Hs	molecular function	144	3.15e-37
WW domain binding	Hs	molecular function	144	3.15e-37

GO (InterProScan)

4 results

GO Term	Analysis	Type	e-value
DNA binding	SUPERFAMILY	molecular function	2.88E-23
transcription factor activity, sequence-specific DNA binding	SMART	molecular function	8.5E-9
nucleus	Pfam	cellular component	9.1E-14
regulation of transcription, DNA-templated	SUPERFAMILY	biological process	2.88E-23