Gene Card
Best human hits
CUL1; CUL2; CUL3
Species
Unique Gene ID
Cisavi.g00005125
Gene Model ID
Cisavi.CG.ENS81.R25.125952-142845
Location
R25:125951..142845
Transcript Models and Sequences
Cisavi.CG.ENS81.R25.125952-142845.10808.t
Cisavi.CG.ENS81.R25.125952-142845.10809.t
Cisavi.CG.ENS81.R25.125952-142845.10810.t
Cisavi.CG.ENS81.R25.125952-142845.10811.t
Cisavi.CG.ENS81.R25.125952-142845.10812.t
Cisavi.CG.ENS81.R25.125952-142845.10813.t
Cisavi.CG.ENS81.R25.125952-142845.10814.t
Cisavi.CG.ENS81.R25.125952-142845.10815.t
Cisavi.CG.ENS81.R25.125952-142845.10816.t
Cisavi.CG.ENS81.R25.125952-142845.10817.t
n/a
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| IPR Term | Analysis | Definition |
|---|---|---|
| Cullin_homology | ProSiteProfiles | Cullin homology domain |
| Cullin_CS | ProSitePatterns | Cullin, conserved site |
| WH-like_DNA-bd_sf | Gene3D | Winged helix-like DNA-binding domain superfamily |
| Cullin_N | Pfam | Cullin, N-terminal |
| Cullin_homology | SMART | Cullin homology domain |
| Cullin_neddylation_domain | SMART | Cullin protein, neddylation domain |
| Cullin_repeat-like_dom_sf | SUPERFAMILY | Cullin repeat-like-containing domain superfamily |
| Cullin_neddylation_domain | Pfam | Cullin protein, neddylation domain |
| Cullin_homology_sf | SUPERFAMILY | Cullin homology domain superfamily |
| WH_DNA-bd_sf | SUPERFAMILY | Winged helix DNA-binding domain superfamily |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 337 | 2.56e-104 |
| ubiquitin-protein transferase activity | Hs | molecular function | 1163 | 0.0 |
| Notch binding | Hs | molecular function | 337 | 2.56e-104 |
| protein binding | Hs | molecular function | 1163 | 0.0 |
| nucleus | Hs | cellular component | 337 | 2.56e-104 |
| nucleoplasm | Hs | cellular component | 1163 | 0.0 |
| nucleolus | Hs | cellular component | 450 | 1.82e-147 |
| cytoplasm | Hs | cellular component | 337 | 2.56e-104 |
| Golgi apparatus | Hs | cellular component | 337 | 2.56e-104 |
| polar microtubule | Hs | cellular component | 337 | 2.56e-104 |
| cytosol | Hs | cellular component | 1163 | 0.0 |
| membrane | Hs | cellular component | 337 | 2.56e-104 |
| SCF ubiquitin ligase complex | Hs | cellular component | 1163 | 0.0 |
| cyclin binding | Hs | molecular function | 337 | 2.56e-104 |
| VCB complex | Hs | cellular component | 450 | 1.82e-147 |
| POZ domain binding | Hs | molecular function | 337 | 2.56e-104 |
| cullin-RING ubiquitin ligase complex | Hs | cellular component | 1163 | 0.0 |
| Cul2-RING ubiquitin ligase complex | Hs | cellular component | 450 | 1.82e-147 |
| Cul3-RING ubiquitin ligase complex | Hs | cellular component | 337 | 2.56e-104 |
| ubiquitin protein ligase binding | Hs | molecular function | 1163 | 0.0 |
| sperm flagellum | Hs | cellular component | 337 | 2.56e-104 |
| protein homodimerization activity | Hs | molecular function | 337 | 2.56e-104 |
| protein heterodimerization activity | Hs | molecular function | 337 | 2.56e-104 |
| ubiquitin protein ligase activity | Hs | molecular function | 1163 | 0.0 |
| extracellular exosome | Hs | cellular component | 337 | 2.56e-104 |
| Parkin-FBXW7-Cul1 ubiquitin ligase complex | Hs | cellular component | 1163 | 0.0 |
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| ubiquitin-dependent protein catabolic process | Pfam | biological process | 4.4E-194 |
| cullin-RING ubiquitin ligase complex | ProSitePatterns | cellular component | |
| ubiquitin protein ligase binding | Pfam | molecular function | 4.4E-194 |


