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Gene Card

Best human hits

RYR1; RYR2; RYR3

Species

C.savignyi

Unique Gene ID

Cisavi.g00007556

Gene Model ID

Cisavi.CG.ENS81.R411.31955-96222

Location

R411:31954..96222

Transcript Models and Sequences

  Cisavi.CG.ENS81.R411.31955-96222.01543.t
Cisavi.CG.ENS81.R411.31955-96222.01544.t
Cisavi.CG.ENS81.R411.31955-96222.01545.t
Cisavi.CG.ENS81.R411.31955-96222.01546.t
Cisavi.CG.ENS81.R411.31955-96222.01547.t
Cisavi.CG.ENS81.R411.31955-96222.01548.t
Cisavi.CG.ENS81.R411.31955-96222.01549.t
Cisavi.CG.ENS81.R411.31955-96222.01550.t
Cisavi.CG.ENS81.R411.31955-96222.01551.t
Cisavi.CG.ENS81.R411.31955-96222.01552.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

19 results

IPR Term Analysis Definition
MIR_motif ProSiteProfiles MIR motif
Ryanrecept_TM4-6 Pfam Ryanodine Receptor TM 4-6
SPRY_dom Pfam SPRY domain
MIR_motif Pfam MIR motif
RIH_assoc-dom Pfam RyR/IP3R Homology associated domain
MIR_dom_sf SUPERFAMILY Mir domain superfamily
B30.2/SPRY ProSiteProfiles B30.2/SPRY domain
Ryan_recept PRINTS Ryanodine receptor
Ryanodine_rcpt Pfam Ryanodine receptor Ryr
SPRY_dom SMART SPRY domain
Ryanodine_recept-rel PANTHER Ryanodine receptor-related
Ion_trans_dom Pfam Ion transport domain
RIH_dom Pfam RIH domain
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
MIR_motif SMART MIR motif
ConA-like_dom_sf SUPERFAMILY Concanavalin A-like lectin/glucanase domain superfamily
SPRY1_RyR CDD Ryanodine receptor, SPRY domain 1
Ins145_P3_rcpt Pfam Inositol 1,4,5-trisphosphate/ryanodine receptor
ARM-type_fold SUPERFAMILY Armadillo-type fold

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

83 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
response to hypoxia Hs biological process
protease binding Hs molecular function
regulation of heart rate Hs biological process
embryonic heart tube morphogenesis Hs biological process
outflow tract morphogenesis Hs biological process
ion channel activity Hs molecular function
ryanodine-sensitive calcium-release channel activity Hs molecular function
voltage-gated calcium channel activity Hs molecular function
calcium channel activity Hs molecular function
binding Hs molecular function
calcium ion binding Hs molecular function
detection of calcium ion Hs biological process
protein binding Hs molecular function
calmodulin binding Hs molecular function
ATP binding Hs molecular function
cell Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
smooth endoplasmic reticulum Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
cell cortex Hs cellular component
ion transport Hs biological process
calcium ion transport Hs biological process
cellular calcium ion homeostasis Hs biological process
muscle contraction Hs biological process
multicellular organism development Hs biological process
positive regulation of heart rate Hs biological process
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Hs biological process
regulation of cardiac muscle contraction by calcium ion signaling Hs biological process
junctional sarcoplasmic reticulum membrane Hs cellular component
terminal cisterna Hs cellular component
calcium-release channel activity Hs molecular function
membrane Hs cellular component
integral component of membrane Hs cellular component
sarcoplasmic reticulum Hs cellular component
calcium-mediated signaling Hs biological process
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
sarcomere Hs cellular component
Z disc Hs cellular component
junctional membrane complex Hs cellular component
T-tubule Hs cellular component
BMP signaling pathway Hs biological process
response to caffeine Hs biological process
organelle membrane Hs cellular component
integral component of organelle membrane Hs cellular component
I band Hs cellular component
macromolecular complex Hs cellular component
sarcoplasmic reticulum membrane Hs cellular component
ion transmembrane transport Hs biological process
protein kinase A catalytic subunit binding Hs molecular function
protein kinase A regulatory subunit binding Hs molecular function
calcium channel complex Hs cellular component
identical protein binding Hs molecular function
intracellular membrane-bounded organelle Hs cellular component
skin development Hs biological process
protein self-association Hs molecular function
suramin binding Hs molecular function
ion channel binding Hs molecular function
metal ion binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
skeletal muscle fiber development Hs biological process
calcium-induced calcium release activity Hs molecular function
release of sequestered calcium ion into cytosol Hs biological process
positive regulation of sequestering of calcium ion Hs biological process
protein homotetramerization Hs biological process
regulation of cytosolic calcium ion concentration Hs biological process
negative regulation of cytosolic calcium ion concentration Hs biological process
response to redox state Hs biological process
transmembrane transport Hs biological process
regulation of cardiac muscle contraction Hs biological process
cardiac muscle contraction Hs biological process
canonical Wnt signaling pathway Hs biological process
extracellular exosome Hs cellular component
calcium ion transmembrane transport Hs biological process
cellular response to calcium ion Hs biological process
organic cyclic compound binding Hs molecular function
regulation of atrial cardiac muscle cell action potential Hs biological process
positive regulation of calcium-transporting ATPase activity Hs biological process
regulation of cardiac conduction Hs biological process
ryanodine receptor complex Hs cellular component

GO (Blast)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 2143 0.0
protease binding Hs molecular function 2143 0.0
ion channel activity Hs molecular function 2774 0.0
ryanodine-sensitive calcium-release channel activity Hs molecular function 2774 0.0
voltage-gated calcium channel activity Hs molecular function 2143 0.0
calcium channel activity Hs molecular function 2774 0.0
binding Hs molecular function 2546 0.0
calcium ion binding Hs molecular function 2774 0.0
protein binding Hs molecular function 2774 0.0
calmodulin binding Hs molecular function 2774 0.0
ATP binding Hs molecular function 2143 0.0
cell Hs cellular component 2774 0.0
cytoplasm Hs cellular component 2143 0.0
endoplasmic reticulum Hs cellular component 2546 0.0
smooth endoplasmic reticulum Hs cellular component 2774 0.0
plasma membrane Hs cellular component 2774 0.0
integral component of plasma membrane Hs cellular component 2143 0.0
cell cortex Hs cellular component 2143 0.0
junctional sarcoplasmic reticulum membrane Hs cellular component 2774 0.0
terminal cisterna Hs cellular component 2143 0.0
calcium-release channel activity Hs molecular function 2774 0.0
membrane Hs cellular component 2774 0.0
integral component of membrane Hs cellular component 2774 0.0
sarcoplasmic reticulum Hs cellular component 2774 0.0
enzyme binding Hs molecular function 2774 0.0
protein kinase binding Hs molecular function 2774 0.0
sarcomere Hs cellular component 2774 0.0
Z disc Hs cellular component 2774 0.0
junctional membrane complex Hs cellular component 2143 0.0
T-tubule Hs cellular component 2143 0.0
organelle membrane Hs cellular component 2546 0.0
integral component of organelle membrane Hs cellular component 2143 0.0
I band Hs cellular component 2143 0.0
macromolecular complex Hs cellular component 2774 0.0
sarcoplasmic reticulum membrane Hs cellular component 2774 0.0
protein kinase A catalytic subunit binding Hs molecular function 2774 0.0
protein kinase A regulatory subunit binding Hs molecular function 2774 0.0
calcium channel complex Hs cellular component 2774 0.0
identical protein binding Hs molecular function 2774 0.0
intracellular membrane-bounded organelle Hs cellular component 2546 0.0
protein self-association Hs molecular function 2774 0.0
suramin binding Hs molecular function 2774 0.0
ion channel binding Hs molecular function 2774 0.0
metal ion binding Hs molecular function 2143 0.0
perinuclear region of cytoplasm Hs cellular component 2546 0.0
calcium-induced calcium release activity Hs molecular function 2774 0.0
extracellular exosome Hs cellular component 2774 0.0
organic cyclic compound binding Hs molecular function 2774 0.0
ryanodine receptor complex Hs cellular component 2143 0.0

GO (InterProScan)

12 results

GO Term Analysis Type e-value
ion channel activity Pfam molecular function 3.2E-15
ryanodine-sensitive calcium-release channel activity PRINTS molecular function 2.1E-66
calcium channel activity Pfam molecular function 2.9E-67
binding SUPERFAMILY molecular function 2.53E-5
protein binding SMART molecular function 1.3E-30
ion transport Pfam biological process 3.2E-15
calcium ion transport PANTHER biological process 0.0
cellular calcium ion homeostasis Pfam biological process 7.0E-52
membrane Pfam cellular component 2.9E-67
integral component of membrane Pfam cellular component 7.0E-52
transmembrane transport Pfam biological process 3.2E-15
calcium ion transmembrane transport Pfam biological process 2.9E-67

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