Aniseed - Gene card

Gene Card

Best human hits

ALOX12B; ALOX5

Species

C.savignyi

Unique Gene ID

Cisavi.g00007746

Gene Model ID

Cisavi.CG.ENS81.R44.451800-457909

Location

R44:451799..457909

Transcript Models and Sequences

Cisavi.CG.ENS81.R44.451800-457909.08319.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term	Analysis	Definition
LipOase_C	ProSiteProfiles	Lipoxygenase, C-terminal
PLAT/LH2_dom_sf	SUPERFAMILY	PLAT/LH2 domain superfamily
LipOase_mml	PRINTS	Lipoxygenase, mammalian
LipOase_CS	ProSitePatterns	Lipoxygenase, conserved site
PLAT/LH2_dom	Pfam	PLAT/LH2 domain
LipOase	PANTHER	Lipoxygenase
LipOase_C_sf	SUPERFAMILY	Lipoxigenase, C-terminal domain superfamily
PLAT/LH2_dom	SMART	PLAT/LH2 domain
LipOase_C	PRINTS	Lipoxygenase, C-terminal
PLAT/LH2_dom	ProSiteProfiles	PLAT/LH2 domain
LipOase_C	Pfam	Lipoxygenase, C-terminal
Catalase_core_sf	Gene3D	Catalase core domain superfamily

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

80 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
catalytic activity	Hs	molecular function
arachidonate 5-lipoxygenase activity	Hs	molecular function
arachidonate 12-lipoxygenase activity	Hs	molecular function
iron ion binding	Hs	molecular function
protein binding	Hs	molecular function
extracellular region	Hs	cellular component
extracellular space	Hs	cellular component
nucleus	Hs	cellular component
nuclear envelope	Hs	cellular component
nuclear envelope lumen	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
protein lipidation	Hs	biological process
lipid metabolic process	Hs	biological process
fatty acid metabolic process	Hs	biological process
sphingolipid metabolic process	Hs	biological process
leukotriene metabolic process	Hs	biological process
inflammatory response	Hs	biological process
positive regulation of gene expression	Hs	biological process
membrane	Hs	cellular component
nuclear matrix	Hs	cellular component
oxidoreductase activity	Hs	molecular function
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Hs	molecular function
cytokine-mediated signaling pathway	Hs	biological process
arachidonic acid metabolic process	Hs	biological process
leukotriene biosynthetic process	Hs	biological process
nuclear membrane	Hs	cellular component
secretory granule lumen	Hs	cellular component
positive regulation of MAPK cascade	Hs	biological process
ceramide biosynthetic process	Hs	biological process
metal ion binding	Hs	molecular function
dioxygenase activity	Hs	molecular function
oxidation-reduction process	Hs	biological process
establishment of skin barrier	Hs	biological process
positive regulation of mucus secretion	Hs	biological process
ficolin-1-rich granule lumen	Hs	cellular component
linoleate 9S-lipoxygenase activity	Hs	molecular function
ossification	Hs	biological process
calcium ion binding	Hs	molecular function
phosphatidylinositol-4,5-bisphosphate binding	Hs	molecular function
intracellular	Hs	cellular component
lipid droplet	Hs	cellular component
cytoskeleton	Hs	cellular component
plasma membrane	Hs	cellular component
phosphatidylethanolamine biosynthetic process	Hs	biological process
apoptotic process	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
lipid binding	Hs	molecular function
positive regulation of cell-substrate adhesion	Hs	biological process
linoleate 13S-lipoxygenase activity	Hs	molecular function
hydrolase activity	Hs	molecular function
lyase activity	Hs	molecular function
isomerase activity	Hs	molecular function
sensory perception of pain	Hs	biological process
fatty acid oxidation	Hs	biological process
extrinsic component of membrane	Hs	cellular component
bone mineralization	Hs	biological process
negative regulation of cell migration	Hs	biological process
positive regulation of actin filament polymerization	Hs	biological process
regulation of epithelial cell differentiation	Hs	biological process
extrinsic component of cytoplasmic side of plasma membrane	Hs	cellular component
positive regulation of heterotypic cell-cell adhesion	Hs	biological process
response to endoplasmic reticulum stress	Hs	biological process
peroxisome proliferator activated receptor signaling pathway	Hs	biological process
arachidonate 8(S)-lipoxygenase activity	Hs	molecular function
wound healing	Hs	biological process
sarcolemma	Hs	cellular component
superoxide anion generation	Hs	biological process
apoptotic cell clearance	Hs	biological process
fat cell differentiation	Hs	biological process
negative regulation of cell cycle	Hs	biological process
negative regulation of growth	Hs	biological process
hepoxilin-epoxide hydrolase activity	Hs	molecular function
arachidonate 15-lipoxygenase activity	Hs	molecular function
hepoxilin A3 synthase activity	Hs	molecular function
extracellular exosome	Hs	cellular component
positive regulation of ERK1 and ERK2 cascade	Hs	biological process
cellular response to calcium ion	Hs	biological process
eoxin A4 synthase activity	Hs	molecular function

GO (Blast)

23 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
catalytic activity	Hs	molecular function	343	2.07e-108
arachidonate 5-lipoxygenase activity	Hs	molecular function	446	2.31e-148
arachidonate 12-lipoxygenase activity	Hs	molecular function	343	2.07e-108
iron ion binding	Hs	molecular function	446	2.31e-148
protein binding	Hs	molecular function	446	2.31e-148
extracellular region	Hs	cellular component	446	2.31e-148
extracellular space	Hs	cellular component	446	2.31e-148
nucleus	Hs	cellular component	446	2.31e-148
nuclear envelope	Hs	cellular component	446	2.31e-148
nuclear envelope lumen	Hs	cellular component	446	2.31e-148
nucleoplasm	Hs	cellular component	446	2.31e-148
cytoplasm	Hs	cellular component	446	2.31e-148
cytosol	Hs	cellular component	446	2.31e-148
membrane	Hs	cellular component	446	2.31e-148
nuclear matrix	Hs	cellular component	446	2.31e-148
oxidoreductase activity	Hs	molecular function	446	2.31e-148
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Hs	molecular function	446	2.31e-148
nuclear membrane	Hs	cellular component	446	2.31e-148
secretory granule lumen	Hs	cellular component	446	2.31e-148
metal ion binding	Hs	molecular function	446	2.31e-148
dioxygenase activity	Hs	molecular function	446	2.31e-148
ficolin-1-rich granule lumen	Hs	cellular component	446	2.31e-148
linoleate 9S-lipoxygenase activity	Hs	molecular function	343	2.07e-108

GO (InterProScan)

7 results

GO Term	Analysis	Type	e-value
iron ion binding	PRINTS	molecular function	6.5E-9
protein binding	SUPERFAMILY	molecular function	6.99E-22
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	PANTHER	molecular function	1.8E-186
metal ion binding	PANTHER	molecular function	1.8E-186
oxidation-reduction process	PANTHER	biological process	1.8E-186
catalase activity	Gene3D	molecular function	5.9E-26
heme binding	Gene3D	molecular function	5.9E-26