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Gene Card

Best human hits

MAP3K10; MAP3K11; MAP3K9

Species

C.savignyi

Unique Gene ID

Cisavi.g00007802

Gene Model ID

Cisavi.CG.ENS81.R451.161659-172776

Location

R451:161658..172776

Transcript Models and Sequences

  Cisavi.CG.ENS81.R451.161659-172776.00056.t
Cisavi.CG.ENS81.R451.161659-172776.00057.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Prot_kinase_dom SMART Protein kinase domain
SH3_domain PRINTS SH3 domain
SH3_domain Pfam SH3 domain
SH3-like_dom_sf SUPERFAMILY SH3-like domain superfamily
SH3_domain SMART SH3 domain
SH3_domain ProSiteProfiles SH3 domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

51 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
nucleotide binding Hs molecular function
activation of MAPKK activity Hs biological process
activation of MAPK activity Hs biological process
transcription corepressor activity Hs molecular function
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
JUN kinase kinase kinase activity Hs molecular function
MAP kinase kinase activity Hs molecular function
MAP kinase kinase kinase activity Hs molecular function
protein tyrosine kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
intracellular Hs cellular component
cytoplasm Hs cellular component
centrosome Hs cellular component
microtubule organizing center Hs cellular component
cytoskeleton Hs cellular component
microtubule Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
protein phosphorylation Hs biological process
apoptotic process Hs biological process
microtubule-based process Hs biological process
signal transduction Hs biological process
smoothened signaling pathway Hs biological process
JNK cascade Hs biological process
activation of JNKK activity Hs biological process
activation of JUN kinase activity Hs biological process
cell death Hs biological process
cell proliferation Hs biological process
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
peptidyl-serine phosphorylation Hs biological process
peptidyl-threonine phosphorylation Hs biological process
peptidyl-tyrosine phosphorylation Hs biological process
mitogen-activated protein kinase kinase binding Hs molecular function
mitogen-activated protein kinase kinase kinase binding Hs molecular function
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
positive regulation of apoptotic process Hs biological process
bHLH transcription factor binding Hs molecular function
negative regulation of sequence-specific DNA binding transcription factor activity Hs biological process
positive regulation of JUN kinase activity Hs biological process
positive regulation of neuron apoptotic process Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of JNK cascade Hs biological process
protein autophosphorylation Hs biological process
Rac GTPase binding Hs molecular function

GO (Blast)

25 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 540 7.39e-174
transcription corepressor activity Hs molecular function 501 3.65e-161
protein kinase activity Hs molecular function 540 7.39e-174
protein serine/threonine kinase activity Hs molecular function 540 7.39e-174
JUN kinase kinase kinase activity Hs molecular function 540 7.39e-174
MAP kinase kinase activity Hs molecular function 540 7.39e-174
MAP kinase kinase kinase activity Hs molecular function 540 7.39e-174
protein tyrosine kinase activity Hs molecular function 540 7.39e-174
protein binding Hs molecular function 540 7.39e-174
ATP binding Hs molecular function 540 7.39e-174
intracellular Hs cellular component 540 7.39e-174
cytoplasm Hs cellular component 540 7.39e-174
centrosome Hs cellular component 510 5.86e-166
microtubule organizing center Hs cellular component 510 5.86e-166
cytoskeleton Hs cellular component 510 5.86e-166
microtubule Hs cellular component 510 5.86e-166
membrane Hs cellular component 510 5.86e-166
kinase activity Hs molecular function 540 7.39e-174
transferase activity Hs molecular function 540 7.39e-174
mitogen-activated protein kinase kinase binding Hs molecular function 510 5.86e-166
mitogen-activated protein kinase kinase kinase binding Hs molecular function 510 5.86e-166
identical protein binding Hs molecular function 510 5.86e-166
protein homodimerization activity Hs molecular function 540 7.39e-174
bHLH transcription factor binding Hs molecular function 501 3.65e-161
Rac GTPase binding Hs molecular function 510 5.86e-166

GO (InterProScan)

4 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 1.5E-66
protein binding SUPERFAMILY molecular function 1.97E-18
ATP binding SMART molecular function 1.2E-59
protein phosphorylation Pfam biological process 1.5E-66

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