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GENE CARD

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Gene Card

Best human hits

DNA2; IGHMBP2; UPF1

Species

C.savignyi

Unique Gene ID

Cisavi.g00009012

Gene Model ID

Cisavi.CG.ENS81.R54.2615028-2628400

Location

R54:2615027..2628400

Transcript Models and Sequences

  Cisavi.CG.ENS81.R54.2615028-2628400.17304.t
Cisavi.CG.ENS81.R54.2615028-2628400.17305.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
Dna2 PANTHER Dna2
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
DNA_replication_fac_Dna2_N Pfam DNA replication factor Dna2, N-terminal

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

42 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
DNA replication checkpoint Hs biological process
nucleotide binding Hs molecular function
telomere maintenance Hs biological process
DNA double-strand break processing Hs biological process
DNA synthesis involved in DNA repair Hs biological process
strand displacement Hs biological process
nuclear chromosome, telomeric region Hs cellular component
DNA binding Hs molecular function
DNA helicase activity Hs molecular function
catalytic activity Hs molecular function
helicase activity Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
mitochondrion Hs cellular component
gamma DNA polymerase complex Hs cellular component
DNA replication Hs biological process
mitochondrial DNA replication Hs biological process
DNA repair Hs biological process
base-excision repair Hs biological process
cellular response to DNA damage stimulus Hs biological process
metabolic process Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
site-specific endodeoxyribonuclease activity, specific for altered base Hs molecular function
5'-flap endonuclease activity Hs molecular function
DNA duplex unwinding Hs biological process
DNA replication, Okazaki fragment processing Hs biological process
mitochondrial nucleoid Hs cellular component
DNA replication, removal of RNA primer Hs biological process
5'-3' DNA helicase activity Hs molecular function
single-stranded DNA-dependent ATPase activity Hs molecular function
mitochondrial DNA repair Hs biological process
G-quadruplex DNA unwinding Hs biological process
positive regulation of DNA replication Hs biological process
metal ion binding Hs molecular function
iron-sulfur cluster binding Hs molecular function
4 iron, 4 sulfur cluster binding Hs molecular function
nucleic acid phosphodiester bond hydrolysis Hs biological process

GO (Blast)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
tRNA binding Hs molecular function 169 8.94e-43
nucleotide binding Hs molecular function 662 0.0
nuclear chromosome, telomeric region Hs cellular component 662 0.0
chromatin Hs cellular component 149 1.51e-36
P-body Hs cellular component 149 1.51e-36
nucleic acid binding Hs molecular function 169 8.94e-43
DNA binding Hs molecular function 662 0.0
DNA helicase activity Hs molecular function 662 0.0
chromatin binding Hs molecular function 149 1.51e-36
single-stranded DNA binding Hs molecular function 169 8.94e-43
RNA binding Hs molecular function 169 8.94e-43
catalytic activity Hs molecular function 662 0.0
ATP-dependent RNA helicase activity Hs molecular function 149 1.51e-36
helicase activity Hs molecular function 662 0.0
nuclease activity Hs molecular function 662 0.0
endonuclease activity Hs molecular function 662 0.0
protein binding Hs molecular function 662 0.0
ATP binding Hs molecular function 662 0.0
nucleus Hs cellular component 662 0.0
nucleoplasm Hs cellular component 662 0.0
cytoplasm Hs cellular component 169 8.94e-43
mitochondrion Hs cellular component 662 0.0
gamma DNA polymerase complex Hs cellular component 662 0.0
cytosol Hs cellular component 149 1.51e-36
DNA-dependent ATPase activity Hs molecular function 169 8.94e-43
transcription factor binding Hs molecular function 169 8.94e-43
RNA-dependent ATPase activity Hs molecular function 169 8.94e-43
zinc ion binding Hs molecular function 169 8.94e-43
membrane Hs cellular component 169 8.94e-43
hydrolase activity Hs molecular function 662 0.0
ATPase activity Hs molecular function 662 0.0
site-specific endodeoxyribonuclease activity, specific for altered base Hs molecular function 662 0.0
5'-flap endonuclease activity Hs molecular function 662 0.0
axon Hs cellular component 169 8.94e-43
growth cone Hs cellular component 169 8.94e-43
intracellular ribonucleoprotein complex Hs cellular component 169 8.94e-43
ATP-dependent 5'-3' RNA helicase activity Hs molecular function 169 8.94e-43
exon-exon junction complex Hs cellular component 149 1.51e-36
telomeric DNA binding Hs molecular function 149 1.51e-36
mitochondrial nucleoid Hs cellular component 662 0.0
cell projection Hs cellular component 169 8.94e-43
ribosome binding Hs molecular function 169 8.94e-43
5'-3' DNA helicase activity Hs molecular function 662 0.0
ATP-dependent 5'-3' DNA helicase activity Hs molecular function 169 8.94e-43
single-stranded DNA-dependent ATPase activity Hs molecular function 662 0.0
supraspliceosomal complex Hs cellular component 149 1.51e-36
metal ion binding Hs molecular function 662 0.0
iron-sulfur cluster binding Hs molecular function 662 0.0
4 iron, 4 sulfur cluster binding Hs molecular function 662 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
5'-flap endonuclease activity PANTHER molecular function 1.6E-180
DNA replication, Okazaki fragment processing PANTHER biological process 1.6E-180
single-stranded DNA-dependent ATPase activity PANTHER molecular function 1.6E-180

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