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GENE CARD

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Gene Card

Best human hits

CASP2; CASP3; CASP7

Species

C.savignyi

Unique Gene ID

Cisavi.g00009101

Gene Model ID

Cisavi.CG.ENS81.R54.461275-467018

Location

R54:461274..467018

Transcript Models and Sequences

  Cisavi.CG.ENS81.R54.461275-467018.10468.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
Caspase_2 PANTHER Caspase-2
Caspase_cys_AS ProSitePatterns Peptidase family C14A, cysteine active site
CARD SMART CARD domain
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
Caspase-like_dom_sf SUPERFAMILY Caspase-like domain superfamily
CARD Pfam CARD domain
Caspase_his_AS ProSitePatterns Peptidase family C14A, His active site
CARD ProSiteProfiles CARD domain
Pept_C14_p20 ProSiteProfiles Peptidase C14, p20 domain
Pept_C14_p10 ProSiteProfiles Peptidase C14, caspase non-catalytic subunit p10
Pept_C14A PRINTS Peptidase C14A, caspase catalytic domain
Pept_C14A CDD Peptidase C14A, caspase catalytic domain
Pept_C14A SMART Peptidase C14A, caspase catalytic domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
neural retina development Hs biological process
cysteine-type endopeptidase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
proteolysis Hs biological process
apoptotic process Hs biological process
activation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
brain development Hs biological process
aging Hs biological process
peptidase activity Hs molecular function
cysteine-type peptidase activity Hs molecular function
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
membrane Hs cellular component
protein processing Hs biological process
hydrolase activity Hs molecular function
enzyme binding Hs molecular function
protein domain specific binding Hs molecular function
ectopic germ cell programmed cell death Hs biological process
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
positive regulation of neuron apoptotic process Hs biological process
cellular response to mechanical stimulus Hs biological process
cysteine-type endopeptidase activity involved in apoptotic process Hs molecular function
apoptotic signaling pathway Hs biological process
extrinsic apoptotic signaling pathway in absence of ligand Hs biological process
execution phase of apoptosis Hs biological process
cysteine-type endopeptidase activity involved in execution phase of apoptosis Hs molecular function
positive regulation of apoptotic signaling pathway Hs biological process

GO (Blast)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
protease binding Hs molecular function 135 3.87e-36
aspartic-type endopeptidase activity Hs molecular function 142 1.59e-37
cysteine-type endopeptidase activity Hs molecular function 246 1.00e-75
cyclin-dependent protein serine/threonine kinase inhibitor activity Hs molecular function 135 3.87e-36
death receptor binding Hs molecular function 135 3.87e-36
protein binding Hs molecular function 246 1.00e-75
nucleus Hs cellular component 246 1.00e-75
nucleoplasm Hs cellular component 142 1.59e-37
cytoplasm Hs cellular component 246 1.00e-75
mitochondrion Hs cellular component 246 1.00e-75
cytosol Hs cellular component 246 1.00e-75
plasma membrane Hs cellular component 135 3.87e-36
peptidase activity Hs molecular function 246 1.00e-75
cysteine-type peptidase activity Hs molecular function 246 1.00e-75
cysteine-type endopeptidase activator activity involved in apoptotic process Hs molecular function 135 3.87e-36
phospholipase A2 activator activity Hs molecular function 135 3.87e-36
membrane Hs cellular component 246 1.00e-75
hydrolase activity Hs molecular function 246 1.00e-75
enzyme binding Hs molecular function 246 1.00e-75
protein domain specific binding Hs molecular function 246 1.00e-75
death-inducing signaling complex Hs cellular component 135 3.87e-36
identical protein binding Hs molecular function 246 1.00e-75
intracellular membrane-bounded organelle Hs cellular component 142 1.59e-37
membrane raft Hs cellular component 135 3.87e-36
cysteine-type endopeptidase activity involved in apoptotic process Hs molecular function 246 1.00e-75
cysteine-type endopeptidase activity involved in execution phase of apoptosis Hs molecular function 246 1.00e-75

GO (InterProScan)

5 results

GO Term Analysis Type e-value
cysteine-type endopeptidase activity ProSiteProfiles molecular function 32.152
proteolysis ProSiteProfiles biological process 32.152
cysteine-type peptidase activity CDD molecular function 2.52934E-86
regulation of apoptotic process SMART biological process 5.7E-17
cysteine-type endopeptidase activity involved in execution phase of apoptosis PANTHER molecular function 2.5E-102