Gene Card
Best human hits
CASP2; CASP3; CASP7
Species
Unique Gene ID
Cisavi.g00009101
Gene Model ID
Cisavi.CG.ENS81.R54.461275-467018
Location
R54:461274..467018
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Caspase_2 | PANTHER | Caspase-2 |
Caspase_cys_AS | ProSitePatterns | Peptidase family C14A, cysteine active site |
CARD | SMART | CARD domain |
DEATH-like_dom_sf | SUPERFAMILY | Death-like domain superfamily |
Caspase-like_dom_sf | SUPERFAMILY | Caspase-like domain superfamily |
CARD | Pfam | CARD domain |
Caspase_his_AS | ProSitePatterns | Peptidase family C14A, His active site |
CARD | ProSiteProfiles | CARD domain |
Pept_C14_p20 | ProSiteProfiles | Peptidase C14, p20 domain |
Pept_C14_p10 | ProSiteProfiles | Peptidase C14, caspase non-catalytic subunit p10 |
Pept_C14A | PRINTS | Peptidase C14A, caspase catalytic domain |
Pept_C14A | CDD | Peptidase C14A, caspase catalytic domain |
Pept_C14A | SMART | Peptidase C14A, caspase catalytic domain |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
protease binding | Hs | molecular function | 135 | 3.87e-36 |
aspartic-type endopeptidase activity | Hs | molecular function | 142 | 1.59e-37 |
cysteine-type endopeptidase activity | Hs | molecular function | 246 | 1.00e-75 |
cyclin-dependent protein serine/threonine kinase inhibitor activity | Hs | molecular function | 135 | 3.87e-36 |
death receptor binding | Hs | molecular function | 135 | 3.87e-36 |
protein binding | Hs | molecular function | 246 | 1.00e-75 |
nucleus | Hs | cellular component | 246 | 1.00e-75 |
nucleoplasm | Hs | cellular component | 142 | 1.59e-37 |
cytoplasm | Hs | cellular component | 246 | 1.00e-75 |
mitochondrion | Hs | cellular component | 246 | 1.00e-75 |
cytosol | Hs | cellular component | 246 | 1.00e-75 |
plasma membrane | Hs | cellular component | 135 | 3.87e-36 |
peptidase activity | Hs | molecular function | 246 | 1.00e-75 |
cysteine-type peptidase activity | Hs | molecular function | 246 | 1.00e-75 |
cysteine-type endopeptidase activator activity involved in apoptotic process | Hs | molecular function | 135 | 3.87e-36 |
phospholipase A2 activator activity | Hs | molecular function | 135 | 3.87e-36 |
membrane | Hs | cellular component | 246 | 1.00e-75 |
hydrolase activity | Hs | molecular function | 246 | 1.00e-75 |
enzyme binding | Hs | molecular function | 246 | 1.00e-75 |
protein domain specific binding | Hs | molecular function | 246 | 1.00e-75 |
death-inducing signaling complex | Hs | cellular component | 135 | 3.87e-36 |
identical protein binding | Hs | molecular function | 246 | 1.00e-75 |
intracellular membrane-bounded organelle | Hs | cellular component | 142 | 1.59e-37 |
membrane raft | Hs | cellular component | 135 | 3.87e-36 |
cysteine-type endopeptidase activity involved in apoptotic process | Hs | molecular function | 246 | 1.00e-75 |
cysteine-type endopeptidase activity involved in execution phase of apoptosis | Hs | molecular function | 246 | 1.00e-75 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
cysteine-type endopeptidase activity | ProSiteProfiles | molecular function | 32.152 |
proteolysis | ProSiteProfiles | biological process | 32.152 |
cysteine-type peptidase activity | CDD | molecular function | 2.52934E-86 |
regulation of apoptotic process | SMART | biological process | 5.7E-17 |
cysteine-type endopeptidase activity involved in execution phase of apoptosis | PANTHER | molecular function | 2.5E-102 |