Gene Card
Best human hits
C3; C5; CD109
Species
Unique Gene ID
Cisavi.g00010680
Gene Model ID
Cisavi.CG.ENS81.R767.7765-20180
Location
R767:7764..20180
Transcript Models and Sequences
Cisavi.CG.ENS81.R767.7765-20180.07101.t
Cisavi.CG.ENS81.R767.7765-20180.07102.t
Cisavi.CG.ENS81.R767.7765-20180.07103.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
18 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Netrin_domain | ProSiteProfiles | Netrin domain |
| Macroglobln_a2 | SMART | Alpha-2-macroglobulin |
| Ig-like_fold | Gene3D | Immunoglobulin-like fold |
| A-macroglobulin_rcpt-bd_sf | Gene3D | Alpha-macroglobulin, receptor-binding domain superfamily |
| A2M_N | Pfam | Alpha-2-macroglobulin, N-terminal |
| Netrin_module_non-TIMP | Pfam | Netrin module, non-TIMP type |
| Terpenoid_cyclase/PrenylTrfase | SUPERFAMILY | Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid |
| A2M_comp | Pfam | Alpha-macroglobulin complement component |
| A2M_N_2 | Pfam | Alpha-2-macroglobulin, N-terminal 2 |
| MacrogloblnA2_thiol-ester-bond | Pfam | Alpha-2-macroglobulin, thiol-ester bond-forming |
| Macroglobln_a2 | Pfam | Alpha-2-macroglobulin |
| A-macroglobulin_rcpt-bd_sf | SUPERFAMILY | Alpha-macroglobulin, receptor-binding domain superfamily |
| A2M_N_2 | SMART | Alpha-2-macroglobulin, N-terminal 2 |
| A-macroglobulin_rcpt-bd | SMART | Alpha-macroglobulin, receptor-binding |
| TIMP-like_OB-fold | SUPERFAMILY | Tissue inhibitor of metalloproteinases-like, OB-fold |
| MacrogloblnA2_CS | ProSitePatterns | Alpha-2-macroglobulin, conserved site |
| A-macroglobulin_rcpt-bd | Pfam | Alpha-macroglobulin, receptor-binding |
| Netrin_module_non-TIMP | SMART | Netrin module, non-TIMP type |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
54 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| activation of MAPK activity | Hs | biological process |
| positive regulation of protein phosphorylation | Hs | biological process |
| immune system process | Hs | biological process |
| serine-type endopeptidase activity | Hs | molecular function |
| endopeptidase inhibitor activity | Hs | molecular function |
| receptor binding | Hs | molecular function |
| protein binding | Hs | molecular function |
| extracellular region | Hs | cellular component |
| membrane attack complex | Hs | cellular component |
| extracellular space | Hs | cellular component |
| endoplasmic reticulum lumen | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| proteolysis | Hs | biological process |
| lipid metabolic process | Hs | biological process |
| fatty acid metabolic process | Hs | biological process |
| phagocytosis, engulfment | Hs | biological process |
| chemotaxis | Hs | biological process |
| inflammatory response | Hs | biological process |
| immune response | Hs | biological process |
| complement activation | Hs | biological process |
| complement activation, alternative pathway | Hs | biological process |
| complement activation, classical pathway | Hs | biological process |
| signal transduction | Hs | biological process |
| cell surface receptor signaling pathway | Hs | biological process |
| G-protein coupled receptor signaling pathway | Hs | biological process |
| chemokine activity | Hs | molecular function |
| positive regulation of vascular endothelial growth factor production | Hs | biological process |
| regulation of triglyceride biosynthetic process | Hs | biological process |
| positive regulation of lipid storage | Hs | biological process |
| negative regulation of endopeptidase activity | Hs | biological process |
| cytolysis | Hs | biological process |
| C5L2 anaphylatoxin chemotactic receptor binding | Hs | molecular function |
| macromolecular complex | Hs | cellular component |
| secretory granule lumen | Hs | cellular component |
| azurophil granule lumen | Hs | cellular component |
| post-translational protein modification | Hs | biological process |
| innate immune response | Hs | biological process |
| positive regulation of G-protein coupled receptor protein signaling pathway | Hs | biological process |
| positive regulation of angiogenesis | Hs | biological process |
| positive regulation of phagocytosis | Hs | biological process |
| regulation of immune response | Hs | biological process |
| cell chemotaxis | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| blood microparticle | Hs | cellular component |
| complement binding | Hs | molecular function |
| complement component C1q binding | Hs | molecular function |
| cell junction | Hs | cellular component |
| carbohydrate binding | Hs | molecular function |
| axon | Hs | cellular component |
| dendrite | Hs | cellular component |
| cell projection | Hs | cellular component |
| neuronal cell body | Hs | cellular component |
| other organism cell | Hs | cellular component |
| synapse | Hs | cellular component |
GO (Blast)
23 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| serine-type endopeptidase activity | Hs | molecular function | 227 | 9.15e-60 |
| endopeptidase inhibitor activity | Hs | molecular function | 227 | 9.15e-60 |
| serine-type endopeptidase inhibitor activity | Hs | molecular function | 202 | 4.67e-52 |
| receptor binding | Hs | molecular function | 227 | 9.15e-60 |
| protein binding | Hs | molecular function | 227 | 9.15e-60 |
| extracellular region | Hs | cellular component | 227 | 9.15e-60 |
| membrane attack complex | Hs | cellular component | 197 | 2.12e-50 |
| extracellular space | Hs | cellular component | 227 | 9.15e-60 |
| endoplasmic reticulum lumen | Hs | cellular component | 227 | 9.15e-60 |
| plasma membrane | Hs | cellular component | 227 | 9.15e-60 |
| chemokine activity | Hs | molecular function | 197 | 2.12e-50 |
| cell surface | Hs | cellular component | 202 | 4.67e-52 |
| membrane | Hs | cellular component | 202 | 4.67e-52 |
| peptidase inhibitor activity | Hs | molecular function | 202 | 4.67e-52 |
| platelet alpha granule membrane | Hs | cellular component | 202 | 4.67e-52 |
| anchored component of membrane | Hs | cellular component | 202 | 4.67e-52 |
| C5L2 anaphylatoxin chemotactic receptor binding | Hs | molecular function | 227 | 9.15e-60 |
| macromolecular complex | Hs | cellular component | 227 | 9.15e-60 |
| secretory granule lumen | Hs | cellular component | 227 | 9.15e-60 |
| azurophil granule lumen | Hs | cellular component | 227 | 9.15e-60 |
| transforming growth factor beta binding | Hs | molecular function | 202 | 4.67e-52 |
| extracellular exosome | Hs | cellular component | 227 | 9.15e-60 |
| blood microparticle | Hs | cellular component | 227 | 9.15e-60 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| endopeptidase inhibitor activity | SMART | molecular function | 3.0E-19 |
| protein binding | ProSiteProfiles | molecular function | 9.677 |
| extracellular region | Gene3D | cellular component | 6.6E-122 |
| extracellular space | Pfam | cellular component | 1.5E-68 |
