Aniseed - Gene card

Gene Card

Best human hits

LEF1; TCF7; TCF7L2

Species

C.savignyi

Unique Gene ID

Cisavi.g00010775

Gene Model ID

Cisavi.CG.ENS81.R77.2752516-2787428

Location

R77:2752515..2787428

Transcript Models and Sequences

Cisavi.CG.ENS81.R77.2752516-2787428.13507.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term	Analysis	Definition
HMG_box_dom	ProSiteProfiles	High mobility group box domain
HMG_box_dom_sf	SUPERFAMILY	High mobility group box domain superfamily
HMG_box_dom	SMART	High mobility group box domain
HMG_box_dom_sf	Gene3D	High mobility group box domain superfamily
HMG_box_dom	Pfam	High mobility group box domain
TCF/LEF	PANTHER	Transcription factor TCF/LEF

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

124 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
nuclear chromatin	Hs	cellular component
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
RNA polymerase II repressing transcription factor binding	Hs	molecular function
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function
blood vessel development	Hs	biological process
branching involved in blood vessel morphogenesis	Hs	biological process
osteoblast differentiation	Hs	biological process
neural crest cell migration	Hs	biological process
somitogenesis	Hs	biological process
epithelial to mesenchymal transition	Hs	biological process
vasculature development	Hs	biological process
sprouting angiogenesis	Hs	biological process
DNA binding	Hs	molecular function
chromatin binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
transcription factor complex	Hs	cellular component
nuclear euchromatin	Hs	cellular component
cytoplasm	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription from RNA polymerase II promoter	Hs	biological process
immune response	Hs	biological process
cell cycle arrest	Hs	biological process
Wnt signaling pathway, calcium modulating pathway	Hs	biological process
beta-catenin binding	Hs	molecular function
transcription factor binding	Hs	molecular function
cell proliferation	Hs	biological process
positive regulation of cell proliferation	Hs	biological process
DNA binding, bending	Hs	molecular function
response to glucose	Hs	biological process
positive regulation of gene expression	Hs	biological process
positive regulation of epithelial to mesenchymal transition	Hs	biological process
Wnt signaling pathway	Hs	biological process
regulation of striated muscle tissue development	Hs	biological process
nuclear body	Hs	cellular component
PML body	Hs	cellular component
protein kinase binding	Hs	molecular function
hypothalamus development	Hs	biological process
forebrain radial glial cell differentiation	Hs	biological process
forebrain neuroblast division	Hs	biological process
forebrain neuron differentiation	Hs	biological process
neural tube development	Hs	biological process
formation of radial glial scaffolds	Hs	biological process
regulation of cell-cell adhesion	Hs	biological process
regulation of Wnt signaling pathway	Hs	biological process
neutrophil differentiation	Hs	biological process
estrogen receptor activity	Hs	molecular function
positive regulation of cell growth	Hs	biological process
embryonic limb morphogenesis	Hs	biological process
estrogen receptor binding	Hs	molecular function
positive regulation of cell migration	Hs	biological process
BMP signaling pathway	Hs	biological process
embryonic genitalia morphogenesis	Hs	biological process
pancreas development	Hs	biological process
positive regulation of insulin secretion	Hs	biological process
positive regulation of protein binding	Hs	biological process
regulation of hormone metabolic process	Hs	biological process
negative regulation of interleukin-13 production	Hs	biological process
negative regulation of interleukin-4 production	Hs	biological process
negative regulation of interleukin-5 production	Hs	biological process
protein-DNA complex	Hs	cellular component
T cell receptor V(D)J recombination	Hs	biological process
nuclear hormone receptor binding	Hs	molecular function
enhancer binding	Hs	molecular function
B cell proliferation	Hs	biological process
regulation of cell proliferation	Hs	biological process
histone binding	Hs	molecular function
glucose homeostasis	Hs	biological process
histone deacetylase binding	Hs	molecular function
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Hs	molecular function
negative regulation of apoptotic process	Hs	biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Hs	biological process
negative regulation of DNA binding	Hs	biological process
steroid hormone mediated signaling pathway	Hs	biological process
negative regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
sequence-specific DNA binding	Hs	molecular function
maintenance of DNA repeat elements	Hs	biological process
histone H3 acetylation	Hs	biological process
histone H4 acetylation	Hs	biological process
transcription regulatory region DNA binding	Hs	molecular function
gamma-catenin binding	Hs	molecular function
fat cell differentiation	Hs	biological process
negative regulation of striated muscle tissue development	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
alpha-beta T cell differentiation	Hs	biological process
positive regulation of protein export from nucleus	Hs	biological process
eye pigmentation	Hs	biological process
paraxial mesoderm formation	Hs	biological process
cell development	Hs	biological process
embryonic digestive tract morphogenesis	Hs	biological process
muscle fiber development	Hs	biological process
sensory perception of taste	Hs	biological process
positive regulation of protein kinase B signaling	Hs	biological process
palate development	Hs	biological process
anatomical structure regression	Hs	biological process
canonical Wnt signaling pathway	Hs	biological process
face morphogenesis	Hs	biological process
cell chemotaxis	Hs	biological process
apoptotic process involved in morphogenesis	Hs	biological process
trachea gland development	Hs	biological process
armadillo repeat domain binding	Hs	molecular function
beta-catenin-TCF7L2 complex	Hs	cellular component
C2H2 zinc finger domain binding	Hs	molecular function
positive regulation of cell proliferation in bone marrow	Hs	biological process
negative regulation of apoptotic process in bone marrow	Hs	biological process
odontoblast differentiation	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
apoptotic process involved in blood vessel morphogenesis	Hs	biological process
beta-catenin-TCF complex	Hs	cellular component
negative regulation of extrinsic apoptotic signaling pathway	Hs	biological process
cytosol	Hs	cellular component
chromatin organization	Hs	biological process

GO (Blast)

39 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nuclear chromatin	Hs	cellular component	219	2.10e-64
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function	181	2.20e-52
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	226	2.76e-68
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	226	2.76e-68
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	181	2.20e-52
RNA polymerase II repressing transcription factor binding	Hs	molecular function	219	2.10e-64
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function	226	2.76e-68
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function	181	2.20e-52
DNA binding	Hs	molecular function	226	2.76e-68
chromatin binding	Hs	molecular function	181	2.20e-52
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	226	2.76e-68
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	Hs	molecular function	181	2.20e-52
protein binding	Hs	molecular function	226	2.76e-68
nucleus	Hs	cellular component	226	2.76e-68
nucleoplasm	Hs	cellular component	226	2.76e-68
transcription factor complex	Hs	cellular component	226	2.76e-68
nuclear euchromatin	Hs	cellular component	226	2.76e-68
cytoplasm	Hs	cellular component	181	2.20e-52
beta-catenin binding	Hs	molecular function	226	2.76e-68
transcription factor binding	Hs	molecular function	219	2.10e-64
DNA binding, bending	Hs	molecular function	181	2.20e-52
nuclear body	Hs	cellular component	226	2.76e-68
PML body	Hs	cellular component	219	2.10e-64
protein kinase binding	Hs	molecular function	219	2.10e-64
estrogen receptor activity	Hs	molecular function	181	2.20e-52
estrogen receptor binding	Hs	molecular function	181	2.20e-52
protein-DNA complex	Hs	cellular component	219	2.10e-64
nuclear hormone receptor binding	Hs	molecular function	219	2.10e-64
enhancer binding	Hs	molecular function	181	2.20e-52
histone binding	Hs	molecular function	181	2.20e-52
histone deacetylase binding	Hs	molecular function	181	2.20e-52
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Hs	molecular function	181	2.20e-52
sequence-specific DNA binding	Hs	molecular function	226	2.76e-68
transcription regulatory region DNA binding	Hs	molecular function	226	2.76e-68
gamma-catenin binding	Hs	molecular function	219	2.10e-64
armadillo repeat domain binding	Hs	molecular function	219	2.10e-64
beta-catenin-TCF7L2 complex	Hs	cellular component	219	2.10e-64
C2H2 zinc finger domain binding	Hs	molecular function	181	2.20e-52
beta-catenin-TCF complex	Hs	cellular component	181	2.20e-52

GO (InterProScan)

1 result

GO Term	Analysis	Type	e-value
Wnt signaling pathway	PANTHER	biological process	3.1E-117